Identification
BMDB Protein ID BMDBP00738
Secondary Accession Numbers None
Name ATP synthase subunit gamma, mitochondrial
Synonyms Not Available
Gene Name ATP5F1C
Protein Type Enzyme
Biological Properties
General Function Energy production and conversion
Specific Function Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 13
Locus Not Available
SNPs ATP5F1C
Gene Sequence Not Available
Protein Properties
Number of Residues 298
Molecular Weight 33072.0
Theoretical pI 9.84
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence
>ATP synthase subunit gamma, mitochondrial
MFSRAGVAGLSAWTVQPQWIQVRNMATLKDITRRLKSIKNIQKITKSMKMVAAAKYARAE
RELKPARVYGVGSLALYEKADIKTPEDKKKHLIIGVSSDRGLCGAIHSSVAKQMKSEAAN
LAAAGKEVKIIGVGDKIRSILHRTHSDQFLVTFKEVGRRPPTFGDASVIALELLNSGYEF
DEGSIIFNRFRSVISYKTEEKPIFSLDTISSAESMSIYDDIDADVLRNYQEYSLANIIYY
SLKESTTSEQSARMTAMDNASKNASEMIDKLTLTFNRTRQAVITKELIEIISGAAALD
GenBank ID Protein CAA39064.1
UniProtKB/Swiss-Prot ID P05631
UniProtKB/Swiss-Prot Entry Name ATPG_BOVIN
PDB IDs
GenBank Gene ID X55389
GeneCard ID ATP5F1C
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available