Showing Protein V-type proton ATPase subunit G 1 (BMDBP00758)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00758 |
| Secondary Accession Numbers | None |
| Name | V-type proton ATPase subunit G 1 |
| Synonyms | Not Available |
| Gene Name | ATP6V1G1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in proton transport |
| Specific Function | Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 8 |
| Locus | Not Available |
| SNPs | ATP6V1G1 |
| Gene Sequence |
>357 bp ATGGCCAGTCAGTCGCAGGGCATCCAGCAGCTGCTCCAGGCGGAGAAACGGGCCGCCGAG AAGGTGTCCGAGGCCCGCAAGCGAAAGAACCGGAGGCTGAAGCAGGCTAAAGAAGAAGCC CAGGCTGAAGTTGAACAGTACCGCCTGCAGAGGGAGAAGGAGTTCAAGGCCAAGGAAGCT GCGGCTCTGGGATCCCATGGTAGTTGCAGCACTGAAGTAGAGAAGGACACCCAGGAGAAG ATGACCATCCTTCAAACCTACTTCCAGCAGAACAGGGATGAAGTCTTGGATAACCTCTTG GCCTTTGTCTGCGACATCCGGCCGGAAATCCATGAGAACTACCGCATAAATGGATAG |
| Protein Properties | |
| Number of Residues | 118 |
| Molecular Weight | 13682.0 |
| Theoretical pI | 8.21 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>V-type proton ATPase subunit G 1 MASQSQGIQQLLQAEKRAAEKVSEARKRKNRRLKQAKEEAQAEVEQYRLQREKEFKAKEA AALGSHGSCSTEVEKDTQEKMTILQTYFQQNRDEVLDNLLAFVCDIRPEIHENYRING |
| External Links | |
| GenBank ID Protein | AAB37487.1 |
| UniProtKB/Swiss-Prot ID | P79251 |
| UniProtKB/Swiss-Prot Entry Name | VATG1_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | S82464 |
| GeneCard ID | ATP6V1G1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |