Showing Protein Alanine--glyoxylate aminotransferase 2, mitochondrial (BMDBP00793)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00793 |
| Secondary Accession Numbers | None |
| Name | Alanine--glyoxylate aminotransferase 2, mitochondrial |
| Synonyms | Not Available |
| Gene Name | AGXT2 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Amino acid transport and metabolism |
| Specific Function | Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 20 |
| Locus | Not Available |
| SNPs | AGXT2 |
| Gene Sequence |
>1545 bp ATGACAGGAGCCTGGGGACATTTGCTGAGATCTTTGCACCTGAAAACCTTATCTCTCTGG ATCCCCAAGACGTGCTTTTCCCTTAAGGCCCGTGCTTTCTGGACATCTGTGACCAGGTGC GGTCTTCATACAAAGCCCAGCATGCCGCCATGTGACTTCACACCCGAAAGATACCAGTCC CTGGCCTATAGCCGAGTCCTGGAGATCCATAAGCAACATCTCTCTCCTGTGCACACCGCC TATTTCCCGGAGCCCCTGTTGCTCCACCAGGGACACGTGGAGTGGCTCTTTGATCATGAG GGAAACAGATACCTGGATTTCTTTTCTGGGATTGTCACTGTCAGTGTTGGTCACTGCCAC CCAAAAGTAAACGCAGCGGCGCAAAGGCAGCTGGGCCGCCTGTGGCATACAAGTTCTGTC TTCTTCCACCCTCTGATCCACGAATATGCAGAGAAGCTTTCAGCACTTCTTCCTGAGCCT TTGAAGGTCGTTTTCTTGGTGAACAGTGGTTCAGAAGCCAATGACCTAGCCATGCTGATG GCCAGAGCACACTCAAACAGCACAGACATCATTTCTTTCAGAGGAGCCTACCATGGATGC AGTCCTTACACACTTGGCTTGACAAATGTAGGCATCTATAAGATGGACCTCCCTCATGGG ATGGGCTGCCAACCAACAATGTGCCCAGACATTTTCCATGGCCCTTGGGGAGGAAGCCAC TGCCGAGATTCTCCAGTGCAAACAATTAGGAAGTGCAGCTGTGCGCCAGACTGCTGTCAA GCTAAAGACCAGTATATTGAACAATTCAAAGATACTCTGAGCACTTCTGTGGCCAAATCA ATTGCTGGATTTTTTGCAGAGCCAATTCAAGGGGTGAATGGCGTTGTTCAGTACCCGAAG GGGTTTCTAAAGGAAGCCTTCGAGCTGGTGCGCGAGCGGGGAGGCGTGTGCATTGCAGAT GAAGTGCAGACAGGATTTGGAAGGCTGGGCTCTCACTTCTGGGGCTTCCAAACACACGAT GTCCTGCCAGATATTGTTACCATGGCTAAAGGGATTGGGAATGGCTTTCCCATGGCAGCA GTCGTGACAACTCCAGATATTGCCAAGTCCTTAACCAAGCGCATGCTTCACTTCAATACC TTTGGAGGGAACCCCATGGCCTGCGCCGTTGGTTCAGCAGTGCTTGAGGTGATTAAAGAA GAAAATCTACAAGAAAATAGCCAAGAAGTTGGCACCTATATGTTGCTGAAGTTGGCTAAG CTGCGGGATGAATTTGAAATTGTAGGAGATGTCCGAGGCAAAGGTCTCATGATAGGAATA GAAATGGTGAAGGATAAGGAGAGCCGCCAGCCTCTTCCCCGTGAAGAAGTAAATCAAATC CACCACGACTGCAAATGCATGGGGCTTCTGATTGGCAGAGGCGGCCTTTTCTCTCAGACT TTCCGCATTGCGCCCTCAATGTGCATCACTAAACCAGAAGTTGATTTTGCAGTGGAAGTG TTTCGCTCTGCCTTAATTCAACACATGGAGAGAAGAGCTAAATAA |
| Protein Properties | |
| Number of Residues | 514 |
| Molecular Weight | 57226.0 |
| Theoretical pI | 7.93 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Alanine--glyoxylate aminotransferase 2, mitochondrial MTGAWGHLLRSLHLKTLSLWIPKTCFSLKARAFWTSVTRCGLHTKPSMPPCDFTPERYQS LAYSRVLEIHKQHLSPVHTAYFPEPLLLHQGHVEWLFDHEGNRYLDFFSGIVTVSVGHCH PKVNAAAQRQLGRLWHTSSVFFHPLIHEYAEKLSALLPEPLKVVFLVNSGSEANDLAMLM ARAHSNSTDIISFRGAYHGCSPYTLGLTNVGIYKMDLPHGMGCQPTMCPDIFHGPWGGSH CRDSPVQTIRKCSCAPDCCQAKDQYIEQFKDTLSTSVAKSIAGFFAEPIQGVNGVVQYPK GFLKEAFELVRERGGVCIADEVQTGFGRLGSHFWGFQTHDVLPDIVTMAKGIGNGFPMAA VVTTPDIAKSLTKRMLHFNTFGGNPMACAVGSAVLEVIKEENLQENSQEVGTYMLLKLAK LRDEFEIVGDVRGKGLMIGIEMVKDKESRQPLPREEVNQIHHDCKCMGLLIGRGGLFSQT FRIAPSMCITKPEVDFAVEVFRSALIQHMERRAK |
| External Links | |
| GenBank ID Protein | AAI18403.1 |
| UniProtKB/Swiss-Prot ID | Q17QF0 |
| UniProtKB/Swiss-Prot Entry Name | AGT2_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC118402 |
| GeneCard ID | AGXT2 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |