Showing Protein Lanosterol synthase (BMDBP00804)
Identification | |
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BMDB Protein ID | BMDBP00804 |
Secondary Accession Numbers |
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Name | Lanosterol synthase |
Synonyms | Not Available |
Gene Name | LSS |
Protein Type | Enzyme |
Biological Properties | |
General Function | Translation, ribosomal structure and biogenesis |
Specific Function | Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency. |
Pathways |
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Reactions | Not Available |
GO Classification | Not Available |
Cellular Location | Not Available |
Gene Properties | |
Chromosome Location | 1 |
Locus | Not Available |
SNPs | LSS |
Gene Sequence | Not Available |
Protein Properties | |
Number of Residues | 732 |
Molecular Weight | 83184.0 |
Theoretical pI | 6.82 |
Pfam Domain Function | Not Available |
Signals |
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Transmembrane Regions |
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Protein Sequence |
>Lanosterol synthase MTEGTCLRRRGGPYKTEPATDLSRWRLSNQVGRQTWTYSQEEDPVREQSGLEAHLLGLDT KSFFKDLPKAHTACRGALNGVTFYAALQTEDGHWAGDYGGPLFLLPGLLITCHVANIPLP AGYREEIIRYLRSVQLPDGGWGLHIEDKSTVFGTALNYVSLRILGVGPDDPDLVRARNLL HKKGGAVFIPSWGKFWLAVLNVYSWEGLNTLFPEMWLFPDWMPAHPSTIWCHCRQVYLPM AYCYSTRLSAEEGPLVQSLRQELYLEDYSCIDWAAHRNSVAPDDLYTPHSWLLHVVYAIL NLYERHHSTSLRQWATQKLYEHIAADDRFTKCISIGPISKTINMLVRWHVDGPASAVFQE HVSRIPDYLWLGLDGMKMQGTNGSQIWDTAFAIQALLEARAQHRPEFWSCLRKAHEYLRI SQVPDNFPDYQKYYRHMSKGGFSFSTLDCGWIVADCTAEALKSILLLQEKCPFVSNHVPR ERLFDTVAVLLSLRNPDGGFATYETKRGGHLLELLNPSEVFGDIMIDYTYVECTSAVMQA LKTFHKQFPDHRAGEIRETLEQGLQFCRQKQRPDGSWEGSWGVCFTYGAWFGLEAFACMG HTYHNGVACAEISRACDFLLSRQMADGGWGEDFESCKQRRYVQSAQSQIHNTCWALMGLM AVRHPDVAALERGVSYLLEKQLPNGDWPQENISGVFNKSCAISYTSYRNVFPIWTLGRFS RLHPDPALAGHP |
External Links | |
GenBank ID Protein | ABD24094.1 |
UniProtKB/Swiss-Prot ID | P84466 |
UniProtKB/Swiss-Prot Entry Name | ERG7_BOVIN |
PDB IDs | Not Available |
GenBank Gene ID | DQ372933 |
GeneCard ID | LSS |
GenAtlas ID | Not Available |
HGNC ID | Not Available |
References | |
General References | Not Available |