| Identification |
|---|
| BMDB Protein ID
| BMDBP00806 |
| Secondary Accession Numbers
| None |
| Name
| Dolichol-phosphate mannosyltransferase subunit 1 |
| Synonyms
|
Not Available
|
| Gene Name
| DPM1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Cell wall/membrane/envelope biogenesis |
| Specific Function
| Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins; catalytic subunit of the dolichol-phosphate mannose (DPM) synthase complex. |
| Pathways
|
- Protein glycosylation
- Protein modification
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 13 |
| Locus
| Not Available |
| SNPs
| DPM1 |
| Gene Sequence
|
>783 bp
ATGGCTGCCGAGGAAGCAAGTCGTAGCTCTCCTAGGTTTCGGCGGGAGCCGAAGGGGCGC
GTCTCGCGGCAAGACAAGTATTCAGTGCTTTTGCCCACGTACAACGAGCGCGAGAACTTA
CCGTTCATCGTGTGGCTGCTGGTGAAGAGCTTCTCCGAGAGTGGTTTCAACTATGAAATT
ATAATCATAGATGATGGAAGCCCAGATGGAACAAGGGACGTTGCTGAGCAGTTGGAGAAG
ATCTATGGGTCAGACAGAATTCTTCTAAGGCCACGGGAGAAAAAGTTGGGGCTAGGAACT
GCATATATTCACGGGATGAAACATGCCACAGGCAACTACATAATCATCATGGATGCTGAC
CTCTCACACCATCCAAAATTTATTCCTGAATTCATTAGGAAGCAAAAGGAGGGTAATTTT
GACATTGTTTCCGGAACTCGCTACAAAGGAAATGGCGGTGTATATGGCTGGGATTTGAAA
AGAAAAATAATCAGCCGTGTGGCCAATTTTATAACTCAGATTTTGCTGCGACCAGGAGCA
TCTGATTTAACAGGAAGTTTCAGGTTATACAGAAAAGAAGTTTTACAGAAATTAATAGGA
AAATGTATTTCTAAAGGCTACGTTTTCCAGATGGAGATGATTGTTCGAGCGAGACAGCTG
AATTATACTATTGGCGAGGTTCCAATATCATTTGTGGATCGTGTTTATGGTGAATCCAAG
TTGGGAGGAAATGAAATAGTCTCTTTCTTGAAAGGATTACTGACTCTCTTTGCTACTACA
TAA
|
| Protein Properties |
|---|
| Number of Residues
| 260 |
| Molecular Weight
| 29592.0 |
| Theoretical pI
| 10.09 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 11-33
- 56-76
- 93-114
- 132-152
|
| Protein Sequence
|
>Dolichol-phosphate mannosyltransferase
MAAEEASRSSPRFRREPKGRVSRQDKYSVLLPTYNERENLPFIVWLLVKSFSESGFNYEI
IIIDDGSPDGTRDVAEQLEKIYGSDRILLRPREKKLGLGTAYIHGMKHATGNYIIIMDAD
LSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGVYGWDLKRKIISRVANFITQILLRPGA
SDLTGSFRLYRKEVLQKLIGKCISKGYVFQMEMIVRARQLNYTIGEVPISFVDRVYGESK
LGGNEIVSFLKGLLTLFATT
|
| External Links |
|---|
| GenBank ID Protein
| AAI16152.1 |
| UniProtKB/Swiss-Prot ID
| Q1JQ93 |
| UniProtKB/Swiss-Prot Entry Name
| DPM1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC116151 |
| GeneCard ID
| DPM1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
