| Identification |
|---|
| BMDB Protein ID
| BMDBP00816 |
| Secondary Accession Numbers
| None |
| Name
| Matrix metalloproteinase-20 |
| Synonyms
|
Not Available
|
| Gene Name
| MMP20 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Secondary metabolites biosynthesis, transport and catabolism |
| Specific Function
| Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Cleaves aggrecan at the '360-Ser-|-Phe-361' site. |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 15 |
| Locus
| Not Available |
| SNPs
| MMP20 |
| Gene Sequence
|
>1446 bp
ATGCTCCCTGCATCTGGCCTTGCTGTCCTCCTCGTCACCGCTCTGAAGTTTTCCACCGCA
GCCCCCTCCCTACCTGCAGCCTCCCCCAGGACCTCAAGGAACAACTACCGCCTTGCACAG
GCGTACCTTGACAAGTATTACACAAAGAAAGGAGGGCCCCAGATTGGGGAGATGGTTGCA
AGAGGAGGCAATTCCACGGTTAAAAAGATTAAGGAGCTGCAGGAGTTCTTCGGCCTCCGA
GTCACCGGGAAGTTAGACCGAGCTACCATGGACGTGATCAAGAGGCCTCGCTGTGGAGTT
CCCGACGTGGCCAACTATCGCCTCTTCCCAGGTGAACCCAAATGGAAAAAAAATACTTTG
ACATACAGAATATCCAAATACACCCCTTCCATGACCCCTGCGGAAGTGGACAGAGCCATG
GAGATGGCCCTGCGGGCCTGGAGCAGCGCCGTCCCTCTGAACTTTGTCAGAATCAATGCG
GGCGAAGCAGACATTATGATCTCTTTTGAAACCGGAGATCACGGGGATTCCTATCCATTT
GATGGGCCTCGAGGGACTCTAGCCCATGCATTTGCACCTGGAGAAGGCCTGGGAGGAGAT
ACACATTTCGACAATGCTGAGAAGTGGACTATGGGAACGAATGGTTTCAATTTATTCACC
GTTGCTGCTCATGAATTTGGTCATGCACTGGGCCTGGCCCATTCCACAGACCCGTCAGCA
CTGATGTTCCCAACTTATAAGTATCAGAATCCCTATGGGTTCCGTCTCCCCAAGGACGAT
GTGAAGGGGATCCAGGCACTGTACGGACCTCGGAGAGCATTCTCAGGGAAGCCCACTGCA
CCCCACGGCCCCCCTCATAATCCATCCATCCCTGACCTCTGTGACTCCAACTTATCCTTC
GATGCTGTGACGATGCTGGGGAAGGAGCTCCTGCTCTTCAGGGACCGGATTTTCTGGCGT
CGGCAGGTTCACTTGATGTCAGGGATCCGGCCCAGCACCATCACCAGCTCCTTCCCCCAG
CTTATGTCCAATGTGGATGCAGCTTATGAAGTGGCTGAGAGGGGCACAGCCTACTTCTTT
AAAGGACCTCACTATTGGATAACAAGAGGATTCCAAATGCAAGGTCCTCCTCGGACTATT
TATGACTTTGGGTTCCCAAGATATGTGCAGCGAATAGACGCCGCAGTCTATCTCAAGGAT
GCACAGAAGACCCTTTTCTTTGTGGGAGATGAATACTACAGTTACGATGAAAGAAAAAGG
AAAATGGAAAAAGACTATCCAAAGAGTACTGAAGAAGAATTTTCAGGAGTCAATGGCCAA
ATAGATGCAGCCGTAGAATTAAATGGCTACATTTACTTCTTTTCCGGACCCAAAGCATAC
AAATCTGATACAGAGAAGGAAGATGTGGTTAGTGAGCTGAAATCTAGTTCCTGGATTGGT
TGCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 481 |
| Molecular Weight
| 53781.0 |
| Theoretical pI
| 9.22 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Matrix metalloproteinase-20
MLPASGLAVLLVTALKFSTAAPSLPAASPRTSRNNYRLAQAYLDKYYTKKGGPQIGEMVA
RGGNSTVKKIKELQEFFGLRVTGKLDRATMDVIKRPRCGVPDVANYRLFPGEPKWKKNTL
TYRISKYTPSMTPAEVDRAMEMALRAWSSAVPLNFVRINAGEADIMISFETGDHGDSYPF
DGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSA
LMFPTYKYQNPYGFRLPKDDVKGIQALYGPRRAFSGKPTAPHGPPHNPSIPDLCDSNLSF
DAVTMLGKELLLFRDRIFWRRQVHLMSGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFF
KGPHYWITRGFQMQGPPRTIYDFGFPRYVQRIDAAVYLKDAQKTLFFVGDEYYSYDERKR
KMEKDYPKSTEEEFSGVNGQIDAAVELNGYIYFFSGPKAYKSDTEKEDVVSELKSSSWIG
C
|
| External Links |
|---|
| GenBank ID Protein
| AAB66599.1 |
| UniProtKB/Swiss-Prot ID
| O18767 |
| UniProtKB/Swiss-Prot Entry Name
| MMP20_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF009922 |
| GeneCard ID
| MMP20 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
