Showing Protein Matrix metalloproteinase-20 (BMDBP00816)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00816 |
| Secondary Accession Numbers | None |
| Name | Matrix metalloproteinase-20 |
| Synonyms | Not Available |
| Gene Name | MMP20 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Secondary metabolites biosynthesis, transport and catabolism |
| Specific Function | Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation. Cleaves aggrecan at the '360-Ser-|-Phe-361' site. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 15 |
| Locus | Not Available |
| SNPs | MMP20 |
| Gene Sequence |
>1446 bp ATGCTCCCTGCATCTGGCCTTGCTGTCCTCCTCGTCACCGCTCTGAAGTTTTCCACCGCA GCCCCCTCCCTACCTGCAGCCTCCCCCAGGACCTCAAGGAACAACTACCGCCTTGCACAG GCGTACCTTGACAAGTATTACACAAAGAAAGGAGGGCCCCAGATTGGGGAGATGGTTGCA AGAGGAGGCAATTCCACGGTTAAAAAGATTAAGGAGCTGCAGGAGTTCTTCGGCCTCCGA GTCACCGGGAAGTTAGACCGAGCTACCATGGACGTGATCAAGAGGCCTCGCTGTGGAGTT CCCGACGTGGCCAACTATCGCCTCTTCCCAGGTGAACCCAAATGGAAAAAAAATACTTTG ACATACAGAATATCCAAATACACCCCTTCCATGACCCCTGCGGAAGTGGACAGAGCCATG GAGATGGCCCTGCGGGCCTGGAGCAGCGCCGTCCCTCTGAACTTTGTCAGAATCAATGCG GGCGAAGCAGACATTATGATCTCTTTTGAAACCGGAGATCACGGGGATTCCTATCCATTT GATGGGCCTCGAGGGACTCTAGCCCATGCATTTGCACCTGGAGAAGGCCTGGGAGGAGAT ACACATTTCGACAATGCTGAGAAGTGGACTATGGGAACGAATGGTTTCAATTTATTCACC GTTGCTGCTCATGAATTTGGTCATGCACTGGGCCTGGCCCATTCCACAGACCCGTCAGCA CTGATGTTCCCAACTTATAAGTATCAGAATCCCTATGGGTTCCGTCTCCCCAAGGACGAT GTGAAGGGGATCCAGGCACTGTACGGACCTCGGAGAGCATTCTCAGGGAAGCCCACTGCA CCCCACGGCCCCCCTCATAATCCATCCATCCCTGACCTCTGTGACTCCAACTTATCCTTC GATGCTGTGACGATGCTGGGGAAGGAGCTCCTGCTCTTCAGGGACCGGATTTTCTGGCGT CGGCAGGTTCACTTGATGTCAGGGATCCGGCCCAGCACCATCACCAGCTCCTTCCCCCAG CTTATGTCCAATGTGGATGCAGCTTATGAAGTGGCTGAGAGGGGCACAGCCTACTTCTTT AAAGGACCTCACTATTGGATAACAAGAGGATTCCAAATGCAAGGTCCTCCTCGGACTATT TATGACTTTGGGTTCCCAAGATATGTGCAGCGAATAGACGCCGCAGTCTATCTCAAGGAT GCACAGAAGACCCTTTTCTTTGTGGGAGATGAATACTACAGTTACGATGAAAGAAAAAGG AAAATGGAAAAAGACTATCCAAAGAGTACTGAAGAAGAATTTTCAGGAGTCAATGGCCAA ATAGATGCAGCCGTAGAATTAAATGGCTACATTTACTTCTTTTCCGGACCCAAAGCATAC AAATCTGATACAGAGAAGGAAGATGTGGTTAGTGAGCTGAAATCTAGTTCCTGGATTGGT TGCTAA |
| Protein Properties | |
| Number of Residues | 481 |
| Molecular Weight | 53781.0 |
| Theoretical pI | 9.22 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Matrix metalloproteinase-20 MLPASGLAVLLVTALKFSTAAPSLPAASPRTSRNNYRLAQAYLDKYYTKKGGPQIGEMVA RGGNSTVKKIKELQEFFGLRVTGKLDRATMDVIKRPRCGVPDVANYRLFPGEPKWKKNTL TYRISKYTPSMTPAEVDRAMEMALRAWSSAVPLNFVRINAGEADIMISFETGDHGDSYPF DGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSA LMFPTYKYQNPYGFRLPKDDVKGIQALYGPRRAFSGKPTAPHGPPHNPSIPDLCDSNLSF DAVTMLGKELLLFRDRIFWRRQVHLMSGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFF KGPHYWITRGFQMQGPPRTIYDFGFPRYVQRIDAAVYLKDAQKTLFFVGDEYYSYDERKR KMEKDYPKSTEEEFSGVNGQIDAAVELNGYIYFFSGPKAYKSDTEKEDVVSELKSSSWIG C |
| External Links | |
| GenBank ID Protein | AAB66599.1 |
| UniProtKB/Swiss-Prot ID | O18767 |
| UniProtKB/Swiss-Prot Entry Name | MMP20_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | AF009922 |
| GeneCard ID | MMP20 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |