Showing Protein Methylated-DNA--protein-cysteine methyltransferase (BMDBP00817)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00817 |
| Secondary Accession Numbers | None |
| Name | Methylated-DNA--protein-cysteine methyltransferase |
| Synonyms | Not Available |
| Gene Name | MGMT |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in DNA binding |
| Specific Function | Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | Not Available |
| Locus | Not Available |
| SNPs | MGMT |
| Gene Sequence | Not Available |
| Protein Properties | |
| Number of Residues | 9 |
| Molecular Weight | 967.0 |
| Theoretical pI | 6.02 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Methylated-DNA--protein-cysteine methyltransferase NPIPILTPC |
| External Links | |
| GenBank ID Protein | Not Available |
| UniProtKB/Swiss-Prot ID | P29177 |
| UniProtKB/Swiss-Prot Entry Name | MGMT_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | Not Available |
| GeneCard ID | MGMT |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |