| Identification |
|---|
| BMDB Protein ID
| BMDBP00838 |
| Secondary Accession Numbers
| None |
| Name
| Adenosylhomocysteinase 3 |
| Synonyms
|
Not Available
|
| Gene Name
| AHCYL2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Coenzyme transport and metabolism |
| Specific Function
| May regulate the electrogenic sodium/bicarbonate cotransporter SLC4A4 activity and Mg(2+)-sensitivity. On the contrary of its homolog AHCYL1, does not regulate ITPR1 sensitivity to inositol 1,4,5-trisphosphate (By similarity). |
| Pathways
|
- Amino-acid biosynthesis
- L-homocysteine biosynthesis
- L-homocysteine from S-adenosyl-L-homocysteine: step 1/1
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 4 |
| Locus
| Not Available |
| SNPs
| AHCYL2 |
| Gene Sequence
|
>1836 bp
ATGTCGGTGCAGGTCGTGTCAGCAGCTGCTGCCGCGAAGGTGCCTGAGGTGGAGCTGAAG
GACCTGAGCCCCTCCGAGGCGGAGCCGCAGCTGGGACTGAGCACAGCGGCCGTGAGCGCC
ATGGCCCCCCCAGCGGGTGGTGGGGACCCTGAAGCTCCAGCTCCGGCCGCGGAGCGGCCC
CCAGCCCCCGGTCCGGGATCGGGCCCCGCAGCGGCTCTCAGCCCGGCCGCTGGGAAAGTG
CCTCAGGCGTCGGCCATGAAGCGGAGCGACCCTCACCACCAGCATCAGAGGCACCGGGAC
GGCGGCGAAGCCCTGGTCAGCCCCGACGGCACCGTCACCGAGGCGCCGCGCACAGTCAAG
AAGCAGATCCAATTTGCTGATCAGAAGCAAGAATTCAATAAACGTCCCACCAAAATTGGA
CGTCGCTCTCTGTCTCGTTCGATTTCCCAGTCATCGACTGACAGCTACAGCTCAGCGGCT
TCATATACAGATAGCTCTGATGATGAGACCTCTCCTAGAGACAAACAGCAAAAGAACTCT
AAGGGGAACAGTGACTTCTGTGTCAAGAACATCAAACAGGCAGAGTTTGGACGAAGAGAA
ATTGAAATTGCTGAGCAAGAAATGCCAGCACTGATGGCTTTGCGGAAGAGAGCTCAAGGA
GAGAAACCTTTGGCCGGCGCCAAGATTGTGGGTTGCACACACATCACTGCCCAGACTGCT
GTGCTTATGGAAACTCTGGGAGCTCTGGGAGCACAGTGCCGATGGGCTGCCTGCAACATC
TATTCCACCCTCAACGAAGTGGCTGCTGCTCTAGCAGAAAGTGGATTTCCTGTGTTTGCC
TGGAAAGGAGAGTCAGAAGATGACTTCTGGTGGTGCATTGACAGATGTGTGAATGTGGAG
GGCTGGCAGCCAAACATGATCTTGGATGATGGAGGGGATCTTACTCACTGGATTTATAAG
AAGTATCCCAACATGTTTAAGAAAATCAAGGGCATAGTGGAGGAGAGTGTTACCGGAGTT
CATAGGCTCTACCAGCTATCCAAAGCTGGGAAGCTGTGTGTTCCAGCCATGAATGTCAAT
GACTCAGTCACGAAACAGAAATTTGACAACCTCTACTGTTGCCGTGAATCAATTCTTGAT
GGACTTAAAAGAACAACAGACATGATGTTTGGTGGGAAGCAGGTGGTAGTCTGTGGCTAT
GGAGAGGTCGGGAAGGGGTGCTGTGCTGCCTTGAAAGCTATGGGCTCCATTGTGTATGTG
ACTGAGATCGACCCCATCTGCGCTCTTCAAGCCTGTATGGATGGATTTCGACTGGTGAAA
TTAAATGAGGTCATCCGACAAGTGGATATTGTTATTACCTGTACAGGTAATAAGAATGTG
GTAACCAGAGAGCATTTAGATCGTATGAAGAATAGCTGCATTGTTTGTAACATGGGACAT
TCCAACACGGAGATTGATGTGGCAAGTCTGCGGACACCAGAACTGACGTGGGAGCGAGTG
AGATCCCAAGTTGATCATGTAATATGGCCTGACGGCAAGAGGATAATATTGTTGGCAGAG
GGCCGTCTGCTGAACCTAAGCTGCTCCACAGTGCCTACATTTGTGCTCTCAATCACTGCT
ACAACTCAGGCTCTAGCCTTGATAGAGCTCTACAATGCTCCCGAGGGTCGCTATAAGCAA
GATGTCTACCTGTTGCCCAAGAAAATGGATGAGTATGTGGCCAGCCTACACCTGCCCACC
TTTGATGCCCACCTGACTGAGCTGACAGATGAACAAGCCAAGTATCTAGGGCTCAACAAG
AATGGGCCCTTCAAGCCCAATTACTACAGGTATTAA
|
| Protein Properties |
|---|
| Number of Residues
| 611 |
| Molecular Weight
| 66774.0 |
| Theoretical pI
| 7.39 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Adenosylhomocysteinase
MSVQVVSAAAAAKVPEVELKDLSPSEAEPQLGLSTAAVSAMAPPAGGGDPEAPAPAAERP
PAPGPGSGPAAALSPAAGKVPQASAMKRSDPHHQHQRHRDGGEALVSPDGTVTEAPRTVK
KQIQFADQKQEFNKRPTKIGRRSLSRSISQSSTDSYSSAASYTDSSDDETSPRDKQQKNS
KGNSDFCVKNIKQAEFGRREIEIAEQEMPALMALRKRAQGEKPLAGAKIVGCTHITAQTA
VLMETLGALGAQCRWAACNIYSTLNEVAAALAESGFPVFAWKGESEDDFWWCIDRCVNVE
GWQPNMILDDGGDLTHWIYKKYPNMFKKIKGIVEESVTGVHRLYQLSKAGKLCVPAMNVN
DSVTKQKFDNLYCCRESILDGLKRTTDMMFGGKQVVVCGYGEVGKGCCAALKAMGSIVYV
TEIDPICALQACMDGFRLVKLNEVIRQVDIVITCTGNKNVVTREHLDRMKNSCIVCNMGH
SNTEIDVASLRTPELTWERVRSQVDHVIWPDGKRIILLAEGRLLNLSCSTVPTFVLSITA
TTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPTFDAHLTELTDEQAKYLGLNK
NGPFKPNYYRY
|
| External Links |
|---|
| GenBank ID Protein
| AAI48037.1 |
| UniProtKB/Swiss-Prot ID
| A6QLP2 |
| UniProtKB/Swiss-Prot Entry Name
| SAHH3_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| DAAA02011501 |
| GeneCard ID
| AHCYL2 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
