Showing Protein UDP-glucose 6-dehydrogenase (BMDBP00848)
| Identification | |||
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| BMDB Protein ID | BMDBP00848 | ||
| Secondary Accession Numbers |
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| Name | UDP-glucose 6-dehydrogenase | ||
| Synonyms | Not Available | ||
| Gene Name | UGDH | ||
| Protein Type | Enzyme | ||
| Biological Properties | |||
| General Function | Cell wall/membrane/envelope biogenesis | ||
| Specific Function | Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans (By similarity). Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans (By similarity). | ||
| Pathways |
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| Reactions |
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| GO Classification | Not Available | ||
| Cellular Location | Not Available | ||
| Gene Properties | |||
| Chromosome Location | 6 | ||
| Locus | Not Available | ||
| SNPs | UGDH | ||
| Gene Sequence |
>1485 bp ATGTTTGAAATTAAGAAGATCTGCTGCATCGGTGCAGGCTATGTTGGTGGACCCACGTGT AGTGTCATTGCTCACATGTGCCCCGAAATCAGGGTGACGGTTGTTGATATCAATGAATCA AGAATCAATGCATGGAACTCTCCTACACTTCCTATTTATGAGCCAGGCCTAAAAGAAGTG GTAGAATCCTGTCGAGGAAAAAATTTATTTTTTTCTACCAATATTGATGATGCCATTAAG GAAGCTGATCTTGTGTTTATTTCTGTGAACACACCAACCAAAACCTATGGAATGGGAAAA GGCCGTGCAGCAGATCTGAAGTATATTGAAGCTTGTGCTAGACGCATTGTGCAAAACTCA CACGGGTACAAAATTGTGACTGAGAAAAGCACAGTCCCAGTGCGGGCAGCAGAAAGTATT CGTCGAATATTTGATGCAAACACAAAACCCAACTTGAATTTACAGGTGCTGTCCAACCCT GAGTTCTTGGCAGAAGGAACAGCCATCAAGGACCTGAAGAACCCAGACAGAGTACTGATT GGAGGAGATGAAACCCCAGAGGGCCAGAGAGCTGTGCAAGCACTGTGTGCTGTGTATGAG CACTGGGTTCCCAGAGAAAAGATCCTCACCACTAATACTTGGTCTTCAGAACTTTCCAAA CTGACAGCAAATGCTTTTCTGGCCCAGAGAATCAGCAGCATTAATTCTATAAGTGCCCTC TGTGAAGCAACAGGAGCTGATGTAGAAGAGGTGGCAACAGCCATTGGAATGGACCAGAGA ATTGGAAATAAATTTCTGAAAGCCAGTGTTGGTTTTGGTGGGAGTTGCTTTCAAAAGGAT GTTCTGAATTTGGTTTATCTCTGTGAGGCTCTAAATTTGCCTGAAGTAGCTCGTTATTGG CAGCAGGTTATAGACATGAATGACTACCAGAGAAGGAGGTTTGCTTCCCGGATCATAGAC AGTCTGTTTAATACAGTGACAGATAAGAAGATAGCTATTTTGGGGTTTGCTTTCAAAAAG GACACTGGTGATACAAGAGAGTCATCTAGTATATATATTAGCAAATATTTGATGGATGAA GGTGCACACCTCCATATATATGATCCGAAAGTACCAAGAGAACAGATAGTTGTGGATCTT TCTCATCCAGGAGTTTCAAAGGACGACCAAGTGGCCCGGCTCGTGACCATTTCCAAAGAT CCCTACGAAGCATGTGATGGTGCCCACGCCGTTGTGATTTGCACTGAGTGGGACATGTTT AAGGAACTGGATTATGAACGCATTCATAAAAAAATGCTGAAACCAGCCTTTATCTTTGAC GGACGACGTGTCCTGGACGGGCTCCACAATGAGCTACAAACCATTGGCTTCCAGATTGAA ACAATTGGCAAGAAGGTGTCTTCAAAGAGAATTCCATATGCTCCTTCTGGTGAAATTCCA AAGTTTAGTCTTCAGGATATGCCCAACAAGAAACCCAGAGTATAG |
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| Protein Properties | |||
| Number of Residues | 494 | ||
| Molecular Weight | 55136.0 | ||
| Theoretical pI | 7.64 | ||
| Pfam Domain Function | Not Available | ||
| Signals |
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| Transmembrane Regions | Not Available | ||
| Protein Sequence |
>UDP-glucose 6-dehydrogenase MFEIKKICCIGAGYVGGPTCSVIAHMCPEIRVTVVDINESRINAWNSPTLPIYEPGLKEV VESCRGKNLFFSTNIDDAIKEADLVFISVNTPTKTYGMGKGRAADLKYIEACARRIVQNS HGYKIVTEKSTVPVRAAESIRRIFDANTKPNLNLQVLSNPEFLAEGTAIKDLKNPDRVLI GGDETPEGQRAVQALCAVYEHWVPREKILTTNTWSSELSKLTANAFLAQRISSINSISAL CEATGADVEEVATAIGMDQRIGNKFLKASVGFGGSCFQKDVLNLVYLCEALNLPEVARYW QQVIDMNDYQRRRFASRIIDSLFNTVTDKKIAILGFAFKKDTGDTRESSSIYISKYLMDE GAHLHIYDPKVPREQIVVDLSHPGVSKDDQVARLVTISKDPYEACDGAHAVVICTEWDMF KELDYERIHKKMLKPAFIFDGRRVLDGLHNELQTIGFQIETIGKKVSSKRIPYAPSGEIP KFSLQDMPNKKPRV |
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| External Links | |||
| GenBank ID Protein | AAC64183.1 | ||
| UniProtKB/Swiss-Prot ID | P12378 | ||
| UniProtKB/Swiss-Prot Entry Name | UGDH_BOVIN | ||
| PDB IDs | Not Available | ||
| GenBank Gene ID | AF095792 | ||
| GeneCard ID | UGDH | ||
| GenAtlas ID | Not Available | ||
| HGNC ID | Not Available | ||
| References | |||
| General References | Not Available | ||