Showing Protein Kynurenine--oxoglutarate transaminase 3 (BMDBP00861)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00861 |
| Secondary Accession Numbers | None |
| Name | Kynurenine--oxoglutarate transaminase 3 |
| Synonyms | Not Available |
| Gene Name | KYAT3 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Amino acid transport and metabolism |
| Specific Function | Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). May catalyze the beta-elimination of S-conjugates and Se-conjugates of L-(seleno)cysteine, resulting in the cleavage of the C-S or C-Se bond (By similarity). Has transaminase activity towards L-kynurenine, tryptophan, phenylalanine, serine, cysteine, methionine, histidine, glutamine and asparagine with glyoxylate as an amino group acceptor (in vitro). Has lower activity with 2-oxoglutarate as amino group acceptor (in vitro) (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 3 |
| Locus | Not Available |
| SNPs | KYAT3 |
| Gene Sequence |
>1368 bp ATGTTTTTGGCCTGGGAGAGACTCTGCACCCTTAGCTGTAGACCTAAATTCCTGAAGACA GTTTGGGCTTCAAAAATCCTTGGACTCTCTACTTCTGCTAAAATGTCTTTGAGATTCAAA AATGCAAAACGAATTGAAGGCCTTGATAGCAATATATGGATTGAATTTACCAAACTGGCT GCAGACCCTTCTGTTGTGAATCTTGGCCAAGGCCTTCCAGATATATCCCCTCCTGTATAT GTAAAGGAAGAATTATCCAAGATTGCAGCAATTGATAATCTGAATCAGTACACACGGGGC TTTGGTCATCCATCACTTGTGAAAGCTCTGTCCTGCCTATATGAAAAGTTTTATCACAAT AAAATCAATCCAAATGAAGAAATCCTTGTGACAGTAGGAGCATATGGATCTCTTTTTAAT GCCATTCAAGGATTGATTGATGAGGGGGATGAAGTCATAGTGATAGTGCCTTTCTTTGAC TGCTATGAGTCCATGGTGAGAATGGCTGGAGCAACACCTGTTTTTGTTCCCCTGAGATGT AAACCTGTTGATGGGAAAAAATGCTCTAGTTCTGACTGGACCTTAGATCCTCAAGAACTG GCAAGCAAATTTAATTCCAAAACCAAAGCTATAATACTAAATACTCCACATAACCCCCTT GGCAAGGTGTATACCAAAGAGGAACTCCAAGTAATTGCCGACCTTTGCATCAAATATGAC ACACTCTGCATCAGTGATGAGGTTTATGAATGGCTTGTATATACTGGAAATAAGCATTTT AAAATAGCCACTTTTCCAGGTATGTGGGAGAGAACAATAACCATAGGAAGTGCTGGAAAG ACTTTCAGTGTAACTGGCTGGAAGCTTGGCTGGTCCATTGGTCCTAAACATTTGATAAAA CATTTACAGACAGTTCAGCAAAACACCGTTTATACTTGTGCAACCCCTTTACAGGAAGCC TTGGCTCAAGCTTTCTGGATTGACATCAAGCGCATGGATGACCCAGAATGTTACTTCAAT TCTTTGCCAAAAGAGTTAGAAGTAAAAAGAGATCGGATGGTACATTTACTTGAAAGTGTT GGCCTAAAATCCATAGTTCCTGATGGGGGATACTTCATCATTGCTGACGTGTCTTTGCTA GATGTAGACCTCTTGGATATGAAGGACAGCAATGAACCTTATGACTATAAATTCGTGAAA TGGATGATTAAAAATAAGAAACTGTCAGCCATCCCAGTTTCAGCATTCTGTAATGCAGAA ACCAAATCACAGTTTGAGAAATTTGTGCGATTTTGCTTCATTAAAAAAGACAGTACACTG GATGCCGCTGAAGAAATCATCAAGGCATGGAGTAGACAGAACTCTTGA |
| Protein Properties | |
| Number of Residues | 455 |
| Molecular Weight | 51472.0 |
| Theoretical pI | 7.82 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Kynurenine--oxoglutarate transaminase 3 MFLAWERLCTLSCRPKFLKTVWASKILGLSTSAKMSLRFKNAKRIEGLDSNIWIEFTKLA ADPSVVNLGQGLPDISPPVYVKEELSKIAAIDNLNQYTRGFGHPSLVKALSCLYEKFYHN KINPNEEILVTVGAYGSLFNAIQGLIDEGDEVIVIVPFFDCYESMVRMAGATPVFVPLRC KPVDGKKCSSSDWTLDPQELASKFNSKTKAIILNTPHNPLGKVYTKEELQVIADLCIKYD TLCISDEVYEWLVYTGNKHFKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPKHLIK HLQTVQQNTVYTCATPLQEALAQAFWIDIKRMDDPECYFNSLPKELEVKRDRMVHLLESV GLKSIVPDGGYFIIADVSLLDVDLLDMKDSNEPYDYKFVKWMIKNKKLSAIPVSAFCNAE TKSQFEKFVRFCFIKKDSTLDAAEEIIKAWSRQNS |
| External Links | |
| GenBank ID Protein | AAI20068.1 |
| UniProtKB/Swiss-Prot ID | Q0P5G4 |
| UniProtKB/Swiss-Prot Entry Name | KAT3_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC120067 |
| GeneCard ID | KYAT3 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |