Showing Protein Farnesyl pyrophosphate synthase (BMDBP00864)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00864 |
| Secondary Accession Numbers |
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| Name | Farnesyl pyrophosphate synthase |
| Synonyms | Not Available |
| Gene Name | FDPS |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Coenzyme transport and metabolism |
| Specific Function | Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (By similarity). |
| Pathways |
|
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 3 |
| Locus | Not Available |
| SNPs | FDPS |
| Gene Sequence |
>1062 bp ATGAATGGAGACCAGAAATTGGACGCTTACGCCCAAGAAAGGCAGGATTTCATCCAGCAC TTCTCCCAGATTGTCAAGGTGCTGACTGAGGAGGACATTGGGCATCCAGAGATAGGAGAT GCCATTACCCGACTCAAGGAGGTCCTGGAGTACAATGCCATCGGAGGCAAGTACAATCGG GGTTTGACGGTGGTAATAACCTTCCGGGAGCTTGTGGAGCCTGGGAAACAAGATCCTGAC AGTCTCCAGCGGGCCCTGACTGTGGGCTGGTGTGTGGAACTGCTCCAAGCCTTCTTCCTG GTGTCAGATGACATTATGGACTCATCCCTCACCCGACGGGGGCAGACCTGCTGGTATCAG AAGCCAGGCATAGGTTTGGATGCCATCAATGATGCTTTCCTTCTGGAATCATCCATCTAC CGCCTGTTGAAGCTGTACTGTCGGGAGCAGCCCTATTACCTGGACCTGATCGAGCTCTTC CTGCAGAGTTCTTATCAAACTGAGATCGGACAGACCTTGGACCTCATCACAGCTCCCCAG GGCAACGTGGATCTTGGCAGATTCACAGAAAAGAGGTATAAGTCTATTGTCAAGTACAAG ACAGCTTTCTACTCCTTTTACCTTCCTGTAGCTGCTGCCATGTATATGGCGGGCATTGAT GGGGAGAAGGAGCATGCCCATGCCAAGAAGATCCTGCTAGAGATGGGAGAGTTCTTTCAG ATTCAGGATGATTACCTCGATCTCTTTGGGGACCCCAGCATGACGGGTAAGATCGGCACA GACATCCAGGACAACAAGTGCAGCTGGCTGGTGGTCCAGTGTCTGCAGCGGGCCTCTCCA GAGCAGCGCCAAATCCTGCAGGAGAACTATGGGCAGAAGGAGGCTGAGAAGGTGGCCCGA GTGAAGGCGCTCTACGAGGAGATGAATCTGTCGGCTGTGTACATGCAATACGAGGAAGAC AGTTACAACCACATTATGGGTCTCATTGAGCAGTATGCTGCGCCCCTGCCCCCAGCCATC TTCCTGGGGTTAGCACAAAAGATCTACAAGCGGAAAAAGTGA |
| Protein Properties | |
| Number of Residues | 353 |
| Molecular Weight | 40510.0 |
| Theoretical pI | 4.8 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions | Not Available |
| Protein Sequence |
>Farnesyl pyrophosphate synthetase MNGDQKLDAYAQERQDFIQHFSQIVKVLTEEDIGHPEIGDAITRLKEVLEYNAIGGKYNR GLTVVITFRELVEPGKQDPDSLQRALTVGWCVELLQAFFLVSDDIMDSSLTRRGQTCWYQ KPGIGLDAINDAFLLESSIYRLLKLYCREQPYYLDLIELFLQSSYQTEIGQTLDLITAPQ GNVDLGRFTEKRYKSIVKYKTAFYSFYLPVAAAMYMAGIDGEKEHAHAKKILLEMGEFFQ IQDDYLDLFGDPSMTGKIGTDIQDNKCSWLVVQCLQRASPEQRQILQENYGQKEAEKVAR VKALYEEMNLSAVYMQYEEDSYNHIMGLIEQYAAPLPPAIFLGLAQKIYKRKK |
| External Links | |
| GenBank ID Protein | AAL58886.1 |
| UniProtKB/Swiss-Prot ID | Q8WMY2 |
| UniProtKB/Swiss-Prot Entry Name | FPPS_BOVIN |
| PDB IDs | |
| GenBank Gene ID | AF461050 |
| GeneCard ID | FDPS |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |