Showing Protein NADPH:adrenodoxin oxidoreductase, mitochondrial (BMDBP00878)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00878 |
| Secondary Accession Numbers | None |
| Name | NADPH:adrenodoxin oxidoreductase, mitochondrial |
| Synonyms | Not Available |
| Gene Name | FDXR |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Amino acid transport and metabolism |
| Specific Function | Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. |
| Pathways |
|
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 19 |
| Locus | Not Available |
| SNPs | FDXR |
| Gene Sequence |
>1479 bp GGGCTGGTTCCTCTTCCCAAGCATGGCTCCGCGCTGTTGGCGCTGGTGGCCCTGGTCGTC TTGGACTCGGACTCGGCTGCCTCCTTCCAGGAGCATCCAGAACTTCGGCCAGCACTTCTC CACACAGGAGCAGACCCCCCAGATCTGTGTGGTGGGCAGTGGCCCAGCTGGCTTTTACAC GGCCCAGCACCTGCTAAAGCACCACTCCCGGGCCCACGTGGATATCTACGAGAAACAGCT GGTGCCCTTCCGCCTGGTGCGCGTTTGGCTGGCGCTGACCACCCCGAGGTCAAGAATGTT ACTCAACACCTTTACCCAGACGGCCCGCTCTGACCGCTGTGCCTTCTATGGCAACGTGGA GGTGGGCAGGGATGTGACTGTGCAGGAGCTGCGGGTGTATCGCCTAACCGCCGTGGTGCT GAGCTATGGGGCAGAGGACCATCAGGCCCTGGATATCCCTGGTGAGGAGTTGCCCGGCGT GTTCTCGGCCCGGGCCTTTGTGGGCTGGTACAATGGGCTTCCTGAGAACCGGGAGCTGGC CCCGGACCTGAGCTGTGACACAGCCGTGATTCTGGGGCAGGGGAATGTGGCTCTGGACGT GGCCCGGATCCTGCTGACCCCCCCCGACCACCTGGAGAAAACGGACATCACTGAGGCCGC CCTGGGAGCCCTGAGACAGAGTCGGGTGAAGACGGTGTGGATCGTGGGCCGACGTGGACC CCTACAAGTGGCCTTCACCATAAAGGAGCTTCGGGAGATGATTCAGTTACCAGGAACTCG GCCCATGTTGGATCCTGCGGATTTCTTGGGTCTCCAGGACAGAATCAGGGAGGCCGCTCG CCCGAGGAAGCGGCTGATGGAACTGCTGCTTCGAACAGCCACGGAGAAGCCAGGGGTGGA GGAGGCTGCCCGCCGGGCATCAGCCTCCCGTGCCTGGGGCCTCCGCTTCTTCCGAAGCCC GCAGCAGGTCCTGCGCCTGCCAGATGGGCGGGCGCGACGATCCGCCTGGCAGTCACCAGA ACTGGAGGGCATTGGAGAGGCACACCCGGGCAGTGCCCACTGGGGATGTGGAGGACCTCC CTGTGGGCTGGTGCTGAGCAGCATTGGGTATAAGAGCCGCCCCATCGACCCCAGTGTGCC CTTTGACCCCAAGCTCGGGGTTGTCCCCAATATGGAGGGCCGGGTTGTGGATGTGCCAGG CCTCTACTGCAGCGGCTGGGTGAAGCGGGGACCCACAGGTGTCATCACCACCACCATGAC CGACAGCTTCCTCACCGGCCAGATTCTGCTACAGGACCTGAAGGCCGGGCACCTGCCGTC TGGCCCCAGGCCGGGCTCTGCATTCATCAAGGCCCTGCTGGACAGCCGAGGGGTCTGGCC CGTGTCTTTCTCGGACTGGGAGAAACTGGATGCTGAGGAGGTGTCCCGGGGCCAGGCCTC GGGGAAGCCCAGAGAGAAGCTGCTGGATCCTCAGGAGAT |
| Protein Properties | |
| Number of Residues | 492 |
| Molecular Weight | 54338.0 |
| Theoretical pI | 8.58 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions | Not Available |
| Protein Sequence |
>NADPH:adrenodoxin oxidoreductase, mitochondrial MAPRCWRWWPWSSWTRTRLPPSRSIQNFGQHFSTQEQTPQICVVGSGPAGFYTAQHLLKH HSRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINTFTQTARSDRCAFYGNVEVGRDVTV QELQDAYHAVVLSYGAEDHQALDIPGEELPGVFSARAFVGWYNGLPENRELAPDLSCDTA VILGQGNVALDVARILLTPPDHLEKTDITEAALGALRQSRVKTVWIVGRRGPLQVAFTIK ELREMIQLPGTRPMLDPADFLGLQDRIKEAARPRKRLMELLLRTATEKPGVEEAARRASA SRAWGLRFFRSPQQVLPSPDGRRAAGIRLAVTRLEGIGEATRAVPTGDVEDLPCGLVLSS IGYKSRPIDPSVPFDPKLGVVPNMEGRVVDVPGLYCSGWVKRGPTGVITTTMTDSFLTGQ ILLQDLKAGHLPSGPRPGSAFIKALLDSRGVWPVSFSDWEKLDAEEVSRGQASGKPREKL LDPQEMLRLLGH |
| External Links | |
| GenBank ID Protein | AAA30362.1 |
| UniProtKB/Swiss-Prot ID | P08165 |
| UniProtKB/Swiss-Prot Entry Name | ADRO_BOVIN |
| PDB IDs | |
| GenBank Gene ID | M17029 |
| GeneCard ID | FDXR |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |