Identification
BMDB Protein ID BMDBP00893
Secondary Accession Numbers None
Name NADPH--cytochrome P450 reductase
Synonyms Not Available
Gene Name POR
Protein Type Enzyme
Biological Properties
General Function Inorganic ion transport and metabolism
Specific Function This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 25
Locus Not Available
SNPs POR
Gene Sequence
>2043 bp
ATGAACATGGCAGACTCCAACATGGATGCCGGCACCACCACGTCTGAGATGGTGGCTGAA
GAAGTGTCCCTTTTCAGCACGACGGACGTGATCCTGTTTTCTCTCATCGTGGGTGTCATG
ACATACTGGTTCCTCTTCAGGAAGAAAAAAGAAGAAGTCCCCGAGTTCACCAAGATTCAG
ACCACGACCTCCTCTGTCAAAGACAGAAGCTTCGTGGAGAAGATGAAGAAGACGGGCAGG
AACATCATCGTGTTCTACGGCTCCCAGACGGGGACTGCTGAGGAGTTTGCCAACCGCCTG
TCCAAGGACGCCCACCGCTATGGGATGCGGGGCATGGCAGCTGACCCCGAGGAGTATGAC
CTGGCCGACCTGAGCAGCCTACCAGAGATTGAGAAAGCCTTGGCCATATTCTGCATGGCC
ACCTACGGCGAGGGGGACCCCACCGACAATGCCCAGGACTTCTACGACTGGCTCCAGGAG
ACGGACGTGGACCTCTCTGGGGTCAAGTACGCGGTGTTTGCCCTTGGGAACAAGACATAC
GAGCATTTCAACGCCATGGGCAAGTACGTGGACAAGCGGCTGGAACAGCTCGGGGCCCAG
CGAATCTTTGATCTGGGGCTGGGCGACGATGACGGGAACCTGGAGGAGGACTTCATCACA
TGGCGAGAGCAGTTCTGGCCAGCCGTGTGCGAGCACTTCGGGGTGGAAGCCACTGGAGAG
GAGTCCAGCATTCGCCAGTACGAACTCATGGTCCACACAGACATGGACATGGCCAAGGTG
TACACGGGCGAGATGGGCCGCCTGAAGAGCTACGAGAACCAGAAACCCCCCTTCGACGCC
AAGAACCCATTCCTGGCTGTTGTCACCACCAACCGGAAGCTGAACCAGGGAACCGAGCGG
CACCTCATGCACCTGGAATTAGACATCTCGGACTCCAAAATCAGGTATGAGTCTGGGGAC
CATGTGGCTGTTTATCCGGCTAATGACTCTGCCCTGGTGAACCAGCTTGGCGAGATCCTG
GGTGCCGACTTGGACATCATCATGTCCCTGAACAACCTTGATGAGGAGTCCAACAAGAAG
CACCCCTTCCCCTGCCCCACCTCCTACCGCACGGCCCTCACCTACTACCTGGACATCACC
AACCCGCCACGCACCAACGTGCTCTACGAGCTGGCGCAGTACGCCTCGGAGCCCACCGAG
CACGAGCAGCTGCGCAAGATGGCCTCCTCGTCAGGCGAGGGCAAGGAGCTATACCTGAGG
TGGGTGCTGGAGGCTCGGCGGCACATCCTGGCCATCCTGCAGGACTACCCGTCCCTGCGG
CCCCCCATCGACCACCTGTGCGAGCTGCTGCCTCGTCTCCAGGCCCGCTACTACTCCATC
GCCTCATCCTCCAAGGTCCACCCCAACTCCGTGCACATCTGCGCCGTGGCCGTGGAGTAC
GAAACCAAGACGGGCCGCATCAACAAGGGCGTGGCCACCAGCTGGTTGCGGGCCAAGGAA
CCGGCCGGGGAGAACGGCGGCCGGGCCCTGGTGCCCATGTACGTGCGCAAGTCCCAGTTC
CGCTTGCCCTTCAAGGCCACCACGCCCGTTATCATGGTGGGCCCTGGCACTGGGGTCGCC
CCCTTCATAGGCTTCATCCAGGAGCGGGCGTGGCTGAGGCAGCAGGGCAAGGAGGTGGGC
GAGACGCTGCTCTACTACGGCTGCCGGCGCTCTGACGAGGACTACCTGTACCGCGAGGAG
CTGGCCGGTTTCCACAAGGACGGCGCCCTCACCCAGCTCAACGTGGCCTTCTCTCGGGAG
CAGCCGCAGAAGGTATACGTGCAGCACTTACTCAAGAAGGACAAGGAGCACCTGTGGAAA
CTCATCCACGAGGGGGGCGCCCACATCTACGTGTGCGGGGACGCTCGGAACATGGCGAGG
GACGTGCAGAACACCTTCTACGACATCGTGGCCGAGCAGGGGGCCATGGAGCACGCCCAG
GCCGTGGACTACGTCAAGAAGCTGATGACCAAGGGCCGCTACTCCCTGGACGTATGGAGC
TAG
Protein Properties
Number of Residues 678
Molecular Weight 77021.0
Theoretical pI 5.45
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 22-42
Protein Sequence
>NADPH--cytochrome P450 reductase
MADSNMDAGTTTSEMVAEEVSLFSTTDVILFSLIVGVMTYWFLFRKKKEEVPEFTKIQTT
TSSVKDRSFVEKMKKTGRNIIVFYGSQTGTAEEFANRLSKDAHRYGMRGMAADPEEYDLA
DLSSLPEIEKALAIFCMATYGEGDPTDNAQDFYDWLQETDVDLSGVKYAVFALGNKTYEH
FNAMGKYVDKRLEQLGAQRIFDLGLGDDDGNLEEDFITWREQFWPAVCEHFGVEATGEES
SIRQYELMVHTDMDMAKVYTGEMGRLKSYENQKPPFDAKNPFLAVVTTNRKLNQGTERHL
MHLELDISDSKIRYESGDHVAVYPANDSALVNQLGEILGADLDIIMSLNNLDEESNKKHP
FPCPTSYRTALTYYLDITNPPRTNVLYELAQYASEPTEHEQLRKMASSSGEGKELYLRWV
LEARRHILAILQDYPSLRPPIDHLCELLPRLQARYYSIASSSKVHPNSVHICAVAVEYET
KTGRINKGVATSWLRAKEPAGENGGRALVPMYVRKSQFRLPFKATTPVIMVGPGTGVAPF
IGFIQERAWLRQQGKEVGETLLYYGCRRSDEDYLYREELAGFHKDGALTQLNVAFSREQP
QKVYVQHLLKKDKEHLWKLIHEGGAHIYVCGDARNMARDVQNTFYDIVAEQGAMEHAQAV
DYVKKLMTKGRYSLDVWS
GenBank ID Protein AAI03400.1
UniProtKB/Swiss-Prot ID Q3SYT8
UniProtKB/Swiss-Prot Entry Name NCPR_BOVIN
PDB IDs
GenBank Gene ID BC103399
GeneCard ID POR
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available