| Identification |
|---|
| BMDB Protein ID
| BMDBP00910 |
| Secondary Accession Numbers
| None |
| Name
| 7-dehydrocholesterol reductase |
| Synonyms
|
Not Available
|
| Gene Name
| DHCR7 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in 7-dehydrocholesterol reductase activity |
| Specific Function
| Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC). |
| Pathways
|
- Cholesterol biosynthesis
- Steroid Biosynthesis
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 29 |
| Locus
| Not Available |
| SNPs
| DHCR7 |
| Gene Sequence
|
>1428 bp
ATGGCTGCGAAGTCCCAGCCCAGCGCCCCTAAAACCAAGAGCACCAGCGGCCTCACCAAC
GGCAACGCTGCAGCCCAAGGCCAGTGGGGCCGAGCCTGGGAGGTGGACTGGTTTTCCCTG
GCGAGCGTCATCTTCCTGCTGCTGTTTGCGCCCTTCATCGTGTACTACTTCATCATGGCC
TGCGACCAGTACGGCTGCTCCCTGACAGTGCCCGTGGCGGACCTCGCCACTGGGCGGGCT
CGGCTCGCCGACATCTGGGCCAGGACGCCGCCCGTGACCGCAAAGGCGGCCCAGATCTAC
ACAGCATGGGTCACGCTCCAGGTGCTTCTGTACATGCTGCTTCCTGACTTCTGCCACAAG
TTTCTTCCGGGCTACGTGGGGGGCGTTCAGGAGGGCGCCGTGACTCCCGCAGGAGCCGTC
AACAAGTATGAGATCAACGGCCTGCAGGCCTGGCTCCTCACGCACCTCCTGTGGTTCGCC
AACGCCCACCTCCTCGGCTGGTTCTCCCCCACCATCATTTTCGACAACTGGATCCCGCTG
CTCTGGTGTGCCAACATCCTGGGCTACACCGTCTCCACCTTCGCCATGGTCAAGGGCTAC
CTCTTCCCCACTGACGCCCGGGAATGCAAATTCACGGGCAATTTCTTTTACAACTACATG
ATGGGCGTTGAGTTTAACCCCCGAATTGGGAAGTGGTTTGACTTCAAGCTCTTCTTCAAT
GGACGCCCCGGGATCGTCGCCTGGACCCTCATCAACCTGTCCTTTGCAGCCAAGCAGCAG
GAGCTCTACGGCCACGTGACCAACTCCATGGTCTTGGTCAACATCCTGCAGGCCATCTAC
GTGCTGGACTTCTTCTGGAACGAAACCTGGTACCTGAAAACCATCGACATCTGCCACGAC
CACTTTGGGTGGTACCTGGGCTGGGGGGACTGCGTCTGGCTGCCATACCTGTACACGCTG
CAGGGCCTGTACCTGGTGTACCACCCCGTGCAGCTGCCCACCTACTACGCGCTGGGCGTC
CTGCTCCTGGGCCTGCTCGGCTACTACATCTTCCGGATGACCAACCACCAGAAGGACCTC
TTCCGCCGCACGGACGGGCGCTGCCTGATCTGGGGCAGGAAGCCCAAGGCCATCGAGTGC
TCCTACACATCAGCCGACGGGCAGAGACACCACAGCAAGCTGCTGGTCTCGGGCTTCTGG
GGCGTGGCCCGCCACTTCAACTACACGGGTGACCTGATGGGCAGCCTGGCGTACTGCCTG
GCCTGCGGCGGCGGCCACCTCCTGCCCTACTTCTACATCATCTTCATGGCCATCCTGCTG
ACCCACCGCTGCCTCCGGGACGAGCACCGCTGTGCCAACAAGTACGGCCGCGACTGGGAG
CACTACACGGCCGCCGTGCCGTACCGCCTGCTCCCTGGCATCTTCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 475 |
| Molecular Weight
| 54271.0 |
| Theoretical pI
| 8.53 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
- 40-60
- 151-173
- 178-200
- 266-286
- 306-326
- 331-351
- 420-440
|
| Protein Sequence
|
>7-dehydrocholesterol reductase
MAAKSQPSAPKTKSTSGLTNGNAAAQGQWGRAWEVDWFSLASVIFLLLFAPFIVYYFIMA
CDQYGCSLTVPVADLATGRARLADIWARTPPVTAKAAQIYTAWVTLQVLLYMLLPDFCHK
FLPGYVGGVQEGAVTPAGAVNKYEINGLQAWLLTHLLWFANAHLLGWFSPTIIFDNWIPL
LWCANILGYTVSTFAMVKGYLFPTDARECKFTGNFFYNYMMGVEFNPRIGKWFDFKLFFN
GRPGIVAWTLINLSFAAKQQELYGHVTNSMVLVNILQAIYVLDFFWNETWYLKTIDICHD
HFGWYLGWGDCVWLPYLYTLQGLYLVYHPVQLPTYYALGVLLLGLLGYYIFRMTNHQKDL
FRRTDGRCLIWGRKPKAIECSYTSADGQRHHSKLLVSGFWGVARHFNYTGDLMGSLAYCL
ACGGGHLLPYFYIIFMAILLTHRCLRDEHRCANKYGRDWEHYTAAVPYRLLPGIF
|
| External Links |
|---|
| GenBank ID Protein
| AAX08942.1 |
| UniProtKB/Swiss-Prot ID
| Q5E9J5 |
| UniProtKB/Swiss-Prot Entry Name
| DHCR7_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BT020925 |
| GeneCard ID
| DHCR7 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
