Showing Protein Nuclear inhibitor of protein phosphatase 1 (BMDBP00911)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00911 |
| Secondary Accession Numbers | None |
| Name | Nuclear inhibitor of protein phosphatase 1 |
| Synonyms | Not Available |
| Gene Name | PPP1R8 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in DNA binding |
| Specific Function | Inhibitor subunit of the major nuclear protein phosphatase-1 (PP-1). It has RNA-binding activity but does not cleave RNA and may target PP-1 to RNA-associated substrates. May also be involved in pre-mRNA splicing. Binds DNA and might act as a transcriptional repressor. Seems to be required for cell proliferation. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 2 |
| Locus | Not Available |
| SNPs | PPP1R8 |
| Gene Sequence |
>1056 bp ATGGCGGCAGCCGCGAACTCCGGCTCCAGCCTCCCGCTGTTCGACTGCCCGACCTGGGCA GGTAAACCCCCTCCTGGTTTACATCTGGATGTAGTCAAAGGAGACAAGCTAATTGAGAAA CTGATTATCGATGAGAAGAAGTATTACTTATTTGGGCGAAACCCTGATTTGTGCGACTTC ACAATTGACCACCAGTCTTGCTCTCGGGTCCATGCTGCCTTGGTCTACCACAAGCATCTG AAGAGAGTTTTCCTTATAGATCTCAACAGTACACACGGCACTTTCTTGGGTCACATTCGG TTGGAGCCTCACAAGCCTCAGCAAATTCCCATCGACTCCACGGTCTCATTTGGTGCATCC ACACGGGCATACACTCTCCGTGAGAAGCCTCAGACATTGCCATCAGCTGTGAAAGGAGAT GAGAAGATGGGTGGAGAGGATGATGAACTCAAGGGCTTACTGGGGCTTCCCGAGGAGGAG ACAGAACTTGATAACCTGACAGAATTCAACACTGCCCACAACAAGCGGATTTCCACTCTC ACCATTGAGGAGGGGAATCTGGACATTCAGAGACCAAAGAGGAAGAGGAAGAACTCACGG GTGACCTTTAGTGAGGATGATGAGATCATCAACCCAGAGGATGTGGATCCCTCGGTTGGT CGCTTTCGGAACATGGTGCAGACTGCAGTGGTCCCAGTCAAGAAGAAGCGGGTGGAGGGC CCTGGCTCCCTGGTCCTGGAGGAATCCGGGAGCAGGCGCATGCAGAACTTTGCCTTCAGT GGAGGACTCTACGGGGGCCTGCCCCCCACGCACAGTGAAGCTGGCTCCCAGCCACACGGC ATCCATGGGACAGCACTCATTGGTGGCTTGCCCATGCCATACCCGAACCTTGCTCCTGAT GTGGACTTGACCCCTGTTGTGCCATCAGCAGTGAACATGAACCCTGCACCAAACCCTGCC GTCTATAACCCCGAAGCTGTCAACGAACCCAAGAAGAAGAAATACGCAAAAGAGGCGTGG CCGGGCAAGAAGCCCACACCTTCCTTACTGATTTGA |
| Protein Properties | |
| Number of Residues | 351 |
| Molecular Weight | 38521.0 |
| Theoretical pI | 7.42 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Nuclear inhibitor of protein phosphatase 1 MAAAANSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDF TIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGAS TRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTL TIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRVEG PGSLVLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPD VDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI |
| External Links | |
| GenBank ID Protein | CAA90625.1 |
| UniProtKB/Swiss-Prot ID | Q28147 |
| UniProtKB/Swiss-Prot Entry Name | PP1R8_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | Z50748 |
| GeneCard ID | PPP1R8 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |