Showing Protein Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A (BMDBP00914)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00914 |
| Secondary Accession Numbers | None |
| Name | Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A |
| Synonyms | Not Available |
| Gene Name | MGAT4A |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in alpha-1,3-mannosylglycoprotein 4-beta-N-ace |
| Specific Function | Glycosyltransferase that participates in the transfer of N-acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Involved in glucose transport by mediating SLC2A2/GLUT2 glycosylation, thereby controlling cell-surface expression of SLC2A2 in pancreatic beta cells. |
| Pathways |
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| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 11 |
| Locus | Not Available |
| SNPs | MGAT4A |
| Gene Sequence |
>1608 bp ATGAGGCTCCGAAATGGAACTGTAGCCACTGTTTTAGCATTTATCACCTCGTTCCTCACT TTATCTTGGTATACAACATGGCAAAATGGGAAAGAAAAAGTGATTGCTTATCAACGAGAA TTTCTTGCTCTGAAAGAACGTCTCCGAATAGCTGAACATCGAATCTCTCAGCGCTCTTCT GAGCTCAGTGCCATTGTACAGCAATTCAAGCGTGTAGAAGCAGAAACAAACAGGAGTAAG GATCCAGTGAATAAATTTTCAGATGATACCCTAAAGATACTAAAGGAGTTAACAAGCAAA AAGTCTCTTCAAGTGCCAAGTATTTATTATCATTTGCCTCATTTATTGCAAAATGAAGGA AGCCTTCAACCTGCCGTGCAGATCGGAAATGGACGAACAGGAGTTTCAATAGTAATGGGA ATTCCTACAGTGAAGAGAGAAGTTAAATCTTACCTCATAGAAACTCTTCATTCCCTTATT GATAATCTGTATCCTGAAGAGAAGTTGGACTGTGTTATAGTAGTCTTCATAGGAGAGACA GATACTGATTATGTAAATGGTGTTGTAGCCAACCTGGAGAAAGAATTTTCTAAAGAAATC AGTTCTGGCTTGGTGGAAATAATATCACCTCCTGAAAGCTATTATCCTGACCTGACGAAC TTAAAGGAGACATTTGGAGATTCTAAAGAAAGAGTAAGATGGAGAACAAAGCAAAACCTA GATTATTGTTTTCTAATGATGTATGCTCAGGAAAAAGGCACATACTACATCCAGCTTGAA GATGATATTATTGTCAAACAGAATTACTTTAACACCATAAAGAATTTTGCACTTCAACTT TCTTCTGAGGAATGGATGATACTTGAGTTCTCCCAGCTGGGATTCATTGGTAAAATGTTT CAAGCACCTGACCTCACTCTGATTGTGGAATTCATATTTATGTTCTATAAGGAGAAGCCC ATCGACTGGCTCTTGGACCATATTCTGTGGGTCAAAGTCTGCAACCCGGAAAAAGATGCA AAACACTGTGATCGACAGAAGGCAAATCTGCGAATTCGTTTCAGACCGTCCCTTTTCCAA CACGTTGGTCTGCATTCTTCACTCACAGGAAAAATTCAGAAACTCACGGATAAAGATTAC ATGAAACCATTACTGCTCAAAATCCATGTAAACCCCCCTGCAGAGGTATCTACTTCTTTG AAGGTCTACCAAGGTCATACACTGGAGAAAACTTACATGGGTGAGGACTTCTTCTGGGCT ATAACCCCAGTAGCTGGAGACTACATCCTATTTAAATTCGACAAGCCAGTCAATGTGGAA AGTTATTTGTTCCATAGTGGCAACCAGGATCATCCAGGGGATATTCTGCTCAACACAACG GTGGAAGTTCTGCCTTTGAAGAGTGAAGGTTTGGACATCAGCAAAGAAACCAAAGACAAA CGATTAGAAGATGGCTATTTCAGAATAGGGAAATTTGAAAACGGTGTTGCGGAAGGGATG GTGGATCCCAGCCTAAACCCCATTTCGGCCTTCCGACTTTCAGTTATTCAGAATTCTGCT GTTTGGGCCATTCTTAATGAGATCCATATTAAAAAAGTCACAAACTGA |
| Protein Properties | |
| Number of Residues | 535 |
| Molecular Weight | 61618.0 |
| Theoretical pI | 7.0 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A MRLRNGTVATVLAFITSFLTLSWYTTWQNGKEKVIAYQREFLALKERLRIAEHRISQRSS ELSAIVQQFKRVEAETNRSKDPVNKFSDDTLKILKELTSKKSLQVPSIYYHLPHLLQNEG SLQPAVQIGNGRTGVSIVMGIPTVKREVKSYLIETLHSLIDNLYPEEKLDCVIVVFIGET DTDYVNGVVANLEKEFSKEISSGLVEIISPPESYYPDLTNLKETFGDSKERVRWRTKQNL DYCFLMMYAQEKGTYYIQLEDDIIVKQNYFNTIKNFALQLSSEEWMILEFSQLGFIGKMF QAPDLTLIVEFIFMFYKEKPIDWLLDHILWVKVCNPEKDAKHCDRQKANLRIRFRPSLFQ HVGLHSSLTGKIQKLTDKDYMKPLLLKIHVNPPAEVSTSLKVYQGHTLEKTYMGEDFFWA ITPVAGDYILFKFDKPVNVESYLFHSGNQDHPGDILLNTTVEVLPLKSEGLDISKETKDK RLEDGYFRIGKFENGVAEGMVDPSLNPISAFRLSVIQNSAVWAILNEIHIKKVTN |
| External Links | |
| GenBank ID Protein | BAA31162.1 |
| UniProtKB/Swiss-Prot ID | O77836 |
| UniProtKB/Swiss-Prot Entry Name | MGT4A_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | AB000628 |
| GeneCard ID | MGAT4A |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |