| Identification |
|---|
| BMDB Protein ID
| BMDBP00920 |
| Secondary Accession Numbers
| None |
| Name
| Bisphosphoglycerate mutase |
| Synonyms
|
Not Available
|
| Gene Name
| BPGM |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Carbohydrate transport and metabolism |
| Specific Function
| Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase (EC 5.4.2.11) activity. |
| Pathways
|
- Gluconeogenesis
- Glycolysis
|
| Reactions
|
| Glyceric acid 1,3-biphosphate → 2,3-Diphosphoglyceric acid |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 10 |
| Locus
| 4q32-q33 |
| SNPs
| BPGM |
| Gene Sequence
|
>780 bp
ATGTCCAAGTACAAACTGATTATGTTAAGACATGGAGAGGGTGCCTGGAATAAAGAGAAC
CGCTTTTGTAGCTGGGTGGATCAGAAACTCAACAGTGATGGACTACAGGAAGCGCGGAAC
TGTGGGAAGCAACTCAAAGCACTAAACTTTGAGTTTGATCTCGTGTTCACATCCATCCTG
AACCGGTCTATCCACACAGCCTGGCTGATCCTGGAAGAGCTGGGGCAGGAGTGGGTTCCT
GTGGAGAGCTCCTGGCGTCTCAACGAGCGTCACTACGGAGCCTTGATCAGTCTCAACAGG
GAGCAGATGGCATTGAATCATGGCGAGGAGCAGGTGAGGCTGTGGAGAAGGAGCTACAAC
GTGACCCCTCCTCCCATCGAGGAGTCCCATCCTTACTACCATGAAATCTACAACGACCGG
AAATATAAAGTGTGTGATGTGCCTTTGGATCAGCTGCCACGATCCGAGAGCTTAAAGGAT
GTTCTGGAGAGACTCCTTCCCTATTGGAATGAGAGGATTGCTCCTGAAGTATTGCGTGGT
AAAACCGTTCTGATATCTGCTCAAGGAAATAGCTGCCGGGCACTCCTGAAATATCTGGAA
GGTATCTCGGATGAAGAAATTATCAACATTACTCTTCCTACTGGGGTCCCCATTCTCCTG
GAACTGGACGAGAACCTGCGTACTGTTGGGCCTCACCAGTTCCTGGGCGACCAAGAGGCT
ATCCAAGCAGCCATTAAGAAAGTTGACGATCAAGGAAAAGTGAAACGAGCTGACAAATAA
|
| Protein Properties |
|---|
| Number of Residues
| 259 |
| Molecular Weight
| 30061.0 |
| Theoretical pI
| 6.41 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Bisphosphoglycerate mutase
MSKYKLIMLRHGEGAWNKENRFCSWVDQKLNSDGLQEARNCGKQLKALNFEFDLVFTSIL
NRSIHTAWLILEELGQEWVPVESSWRLNERHYGALISLNREQMALNHGEEQVRLWRRSYN
VTPPPIEESHPYYHEIYNDRKYKVCDVPLDQLPRSESLKDVLERLLPYWNERIAPEVLRG
KTVLISAQGNSCRALLKYLEGISDEEIINITLPTGVPILLELDENLRTVGPHQFLGDQEA
IQAAIKKVDDQGKVKRADK
|
| External Links |
|---|
| GenBank ID Protein
| AAI02612.1 |
| UniProtKB/Swiss-Prot ID
| Q3T014 |
| UniProtKB/Swiss-Prot Entry Name
| PMGE_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC102611 |
| GeneCard ID
| BPGM |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
