Showing Protein Ornithine decarboxylase (BMDBP00922)
| Identification | |||
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| BMDB Protein ID | BMDBP00922 | ||
| Secondary Accession Numbers |
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| Name | Ornithine decarboxylase | ||
| Synonyms | Not Available | ||
| Gene Name | ODC1 | ||
| Protein Type | Enzyme | ||
| Biological Properties | |||
| General Function | Amino acid transport and metabolism | ||
| Specific Function | Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis. | ||
| Pathways |
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| Reactions |
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| GO Classification | Not Available | ||
| Cellular Location | Not Available | ||
| Gene Properties | |||
| Chromosome Location | 11 | ||
| Locus | Not Available | ||
| SNPs | ODC1 | ||
| Gene Sequence |
>1386 bp ATGAACAGCTTTAGCAATGAAGAGTTTGACTGCCATTTCTTGGATGAAGGCTTTACTGCC AAGGATATTCTGGACCAAAAAATTAATGAAGTTTCTTATTCTGATGATAAGGATGCCTTC TATGTTGCGGACCTGGGAGACATTCTGAAGAAACATCTGAGATGGTTGAAAGCTCTTCCT CGGGTCACCCCCTTTTATGCCGTCAAATGCAATGATAGCAGAACCATAGTGAAGACACTC GCTGCCATTGGGACAGGATTTGACTGTGCCAGCAAGACTGAAATACAATTGGTGCAGAGT CTCGGGGTGCCCCCAGAGAGGATTATCTATGCAAATCCATGTAAACAAGTGTCTCAGATT AAGTATGCTGCCAATAACGGAGTCCAGATGATGACTTTTGATAGTGAAGTTGAGCTGATG AAAGTTGCCAGGGCACATCCAAAGGCCAAGTTGGTTTTACGGATCGCCACTGATGATTCC AAAGCAGTCTGTCGCCTCAGTGTCAAATTTGGTGCCACACTCAAAACCAGCAGGCTTCTT TTGGAACGGGCGAAAGAGCTAGATATTGATGTCATTGGTGTCAGCTTCCACGTGGGAAGT GGCTGTACTGATCCTGAGACCTTTGTGCAGGCCATCTCTGATGCCCGCTGTGTCTTTGAC ATGGGCGCTGAGGTTGGTTTCAACATGTATCTGCTTGATATTGGTGGTGGCTTTCCTGGA TCAGAGGATGTAAAGCTTAAATTTGAAGAGATCACCAGTGTAATCAACCCAGCACTGGAC AAGTATTTTCCATCAGACTCTGGAGTGAGAATCATAGCTGAGCCAGGCAGATACTATGTT GCATCAGCTTTCACGCTCGCAGTTAATATTATTGCCAAAAAACTTGTATTAAAGGAACAG ACAGGCTCTGATGATGAAGAGGAGTCAACTGATCGGACATTTATGTATTATGTGAACGAT GGAGTATATGGGTCATTCAACTGCATCCTTTATGATCACGCACACGTGAAGCCTCTTCTG CAGAAGAGACCCAAACCAGATGAGAAGTATTATTCATCCAGCATCTGGGGACCGACCTGT GACGGCCTGGACCGCATTGTTGAGCGCTGTAACCTGCCTGAGATGCATGTGGGTGATTGG ATGCTCTTTGAGAACATGGGTGCTTACACTGTTGCTGCTGCTTCTACCTTCAATGGATTC CAGAGACCCACCATCTACTATGTGATGTCAGGGCCAACGTGGCAACTGATGCAGCAGATC CGGACCCAGGACTTCCCGCCTGGAGTGGAGGAGCCGGACGTCGGTCCCCTGCCCGTGTCC TGTGCCTGGGAGAGCGGCATGAAGCGGCACTCGGCAGCCTGCGCTTCCACGCGTATTAAC GTGTAG |
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| Protein Properties | |||
| Number of Residues | 461 | ||
| Molecular Weight | 51346.0 | ||
| Theoretical pI | 5.12 | ||
| Pfam Domain Function | Not Available | ||
| Signals |
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| Transmembrane Regions | Not Available | ||
| Protein Sequence |
>Ornithine decarboxylase MNSFSNEEFDCHFLDEGFTAKDILDQKINEVSYSDDKDAFYVADLGDILKKHLRWLKALP RVTPFYAVKCNDSRTIVKTLAAIGTGFDCASKTEIQLVQSLGVPPERIIYANPCKQVSQI KYAANNGVQMMTFDSEVELMKVARAHPKAKLVLRIATDDSKAVCRLSVKFGATLKTSRLL LERAKELDIDVIGVSFHVGSGCTDPETFVQAISDARCVFDMGAEVGFNMYLLDIGGGFPG SEDVKLKFEEITSVINPALDKYFPSDSGVRIIAEPGRYYVASAFTLAVNIIAKKLVLKEQ TGSDDEEESTDRTFMYYVNDGVYGSFNCILYDHAHVKPLLQKRPKPDEKYYSSSIWGPTC DGLDRIVERCNLPEMHVGDWMLFENMGAYTVAAASTFNGFQRPTIYYVMSGPTWQLMQQI RTQDFPPGVEEPDVGPLPVSCAWESGMKRHSAACASTRINV |
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| External Links | |||
| GenBank ID Protein | AAA92339.1 | ||
| UniProtKB/Swiss-Prot ID | P27117 | ||
| UniProtKB/Swiss-Prot Entry Name | DCOR_BOVIN | ||
| PDB IDs | |||
| GenBank Gene ID | M92441 | ||
| GeneCard ID | ODC1 | ||
| GenAtlas ID | Not Available | ||
| HGNC ID | Not Available | ||
| References | |||
| General References | Not Available | ||