Identification
BMDB Protein ID BMDBP00932
Secondary Accession Numbers None
Name Glycerol-3-phosphate acyltransferase 4
Synonyms Not Available
Gene Name GPAT4
Protein Type Enzyme
Biological Properties
General Function Involved in glycerol-3-phosphate O-acyltransferase acti
Specific Function Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone (By similarity). Active against both saturated and unsaturated long-chain fatty acyl-CoAs (By similarity).
Pathways
  • CDP-diacylglycerol biosynthesis
  • CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3
  • Phospholipid metabolism
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 27
Locus Not Available
SNPs GPAT4
Gene Sequence Not Available
Protein Properties
Number of Residues 456
Molecular Weight 52055.0
Theoretical pI 9.65
Pfam Domain Function Not Available
Signals
  • 1-37
Transmembrane Regions
  • 156-176
  • 180-200
Protein Sequence
>Glycerol-3-phosphate acyltransferase 4
MFLLLPFDSLIVSLLGISLTVLFTLLLVFIIVPAVFGVSFGIRKLYMKTLLKIFAWATLR
MERGAKEKNHQLYKPYTNGIIAKDPTSLEEEIKEIRRSGSSKALDNTPEFELSDIFYFCR
KGMETIMDDEVTKRFSAEELESWNLLSRTNYNFQYISLRLTVLWGLGVLIRYCLLLSLRI
ALAFTGISLLVVGTTMVGYLPNGRFKEFLSKHVHLMCYRICVRALTAIITYHDRKNRPRN
GGICVANHTSPIDVIILASDGYYAMVGQVHGGLMGVIQRAMVKACPHVWFERSEVKDRHL
VARRLTEHVQDKSKLPILIFPEGTCINNTSVMMFKKGSFEIGATVYPVAIKYDPQFGDAF
WNSSKYGMVTYLLRMMTSWAIVCSVWYLPPMTRQAEEDAVQFANRVKSAIARQGGLVDLL
WDGGLKREKVKDTFKEEQQKLYSKMIVGNHEDRSRS
GenBank ID Protein ABN50363.1
UniProtKB/Swiss-Prot ID A3FPG8
UniProtKB/Swiss-Prot Entry Name GPAT4_BOVIN
PDB IDs Not Available
GenBank Gene ID EF432784
GeneCard ID GPAT4
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available