| Identification |
|---|
| BMDB Protein ID
| BMDBP00934 |
| Secondary Accession Numbers
| None |
| Name
| Glycerol-3-phosphate acyltransferase 1, mitochondrial |
| Synonyms
|
Not Available
|
| Gene Name
| GPAM |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Lipid transport and metabolism |
| Specific Function
| Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. |
| Pathways
|
- CDP-diacylglycerol biosynthesis
- CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3
- Glycerolipid Metabolism
- Phospholipid Biosynthesis
- Phospholipid metabolism
|
| Reactions
|
| Glycerol 3-phosphate + Palmityl-CoA → LPA(16:0/0:0) + Coenzyme A |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 26 |
| Locus
| Not Available |
| SNPs
| GPAM |
| Gene Sequence
|
>2478 bp
ATGGATGAATCTGCATTGACCCTTGGCACGATAGATGTATCTTATTTGCCAAATTCTTCT
GAATACAGCATTGGTCGGTGTAAGCATGCCACCGAGGAATGGGGTGAGTGTGGTTCCAGG
CCTACTGTCTTCAGATCTGCAACCTTGAAGTGGAAAGAAAGCCTAATGAGCCGGAAGAGG
CCCTTTGTGGGAAGGTGCTGTTATTCCTGTACTCCTCAGAGCTGGGATAAATTTTTCAAC
CCCAGTATCCCGTCTTTGGGTTTGCGGAATGTTATTTATATCAATGAAACGCATACAAGG
CACCGAGGGTGGCTGGCAAGACGTCTTTCTTATGTGCTTTTCATTCAAGAGCGAGATGTC
CATAAAGGCATGTTTGCCACCAACGTAACTGAAAACGTGCTGAACAGCAGTCGAGTACAA
GAGGCAATTGCAGAAGTGGCTGGTGAATTAAACCCTGATGGTTCTGCTCAGCAGCAATCA
AAAGCTGTGAATAAAGTGAAAAAGAAAGCCAGAAAGATCCTTCAAGAAATGGTTGCCACC
GTTTCACCGGCAATGATCAGACTGACTGGATGGGTGCTGCTGAAACTGTTCAACAGCTTC
TTTTGGAATATTCAGATTCACAAGGGTCAACTTGAGATGGTTAAAGCTGCGACTGAGACG
AATTTGCCGCTTATATTTCTGCCAGTTCATAGATCACACATTGACTATCTCCTGCTCACT
TTCATTCTCTTCTGCCATAACATCAAAGCGCCGTACATTGCTTCAGGCAATAATCTCAAC
ATCCCCATCTTCAGTACTTTGATCCATAAGCTTGGAGGCTTTTTCATACGACGGAGGCTA
GATGAGACGCCAGATGGACGGAAAGATATTCTCTATAGAGCTTTACTCCATGGGCATATA
GTTGAACTACTGCGACAGCAGCAGTTCTTGGAGATCTTCCTGGAAGGCACACGCTCAAGA
AGTGGAAAAATCTCCTGTGCTCGGGCAGGACTTCTGTCAGTTGTGGTAGATACACTGTCC
ACCAATACGATCCCAGACATCTTGATAATACCTGGTGGGATCTCTTACGATCGCATTATT
GAGGGTCATTACAATGGCGAACAACTGGGAAAACCCAAGAAGAATGAGAGCCTCTGGAGC
ATAGCAAGAGGCGTTATCAGAATGTTACGAAAAAACTACGGATGTGTCAAAACGGATTTT
GCACAACCATTTTCCTTAAAGGAATATTTAGAAAGCCAAAGTCAGAAACCTGTTTCTGCT
CCACTTTCTTTGGAGCAAGCATTGTTGCCAGCTATACTTCCCTCAAGACCCAGTGGTGCT
GCTGACGAAGGTACAGACATGTCCATTAATGAGTCCAGAAATGCAACAGATGAATCCCGC
CGAAGACTGATTGCACACCTGGCTGAGCACATTCTCTTCACTGCTAGCAAGTCCTGTGCT
ATTATGTCCACGCACATCGTGGCCTGTCTGCTCCTCTACAGACACAGGCAGGGAATTGGC
CTCTTCACATTGGTGGAAGACTTCTTTGTGATGAAGGAGGAAGTCCTGGCTCGTGATTTT
GACTTGGGTTTCTCAGGAAATTCAGAAGATGTAGTCATGCATGCCATACAGTTCCTGGGA
AATTGTATCACAATCACCCACACGAGCAAGAATGATGAGTTTTTTATTACTCCTAGCACA
ACTATCCCATCAGTCTTTGAACTCAACTTCTACAGCAATGGGGTGCTCCATGTCTTTATC
ATGGAGGCCATCATAGCCTGCAGCCTTTATGCAGTTCTGAAGAAGAGGGGCCCAGGAGGA
CCCGCGTCTCCCAGCTTGGTCAGCCAGGAGCAGCTGGTGCACAAGGCTGCCAGCCTGTGC
TATCTGCTCTCCAATGAAGGCACCATCTCTCTCCCCTGCCAGACCTTTTACCAAATTTGC
CATGAAACAGTGGGCAGGTTTATCCAGTATGGCATTCTTATAGTGGCGGAGCAAGATGAT
CAGGAAGATATCAGTCCTGGTCTTGCCGAGCAGCAGTGGGACAAGAAGCTTCCGGAACCT
TTGTCTTGGAGAAGTGATGAAGAAGATGAAGACAGCGATTTTGGTGAGGAGCAACGAGAT
TGCTACCTGAAGGTGAGCCAGTCCAAGGAGCACCAGCAGTTCATCACCTTCCTGCAGAGG
CTCCTCGGGCCTCTGCTGGAGGCGTACAGCTCTGCCGCCGTCTTCATTCACAACTTCGGC
GGTCCTGTCCCCGAGCCTGAATTCCTGCAGAAGCTGCACAAGTACCTGATCACAAGAACC
GAGAGAAGGGTTGCCGTATACGCTGAGAGCGCCACTTACTGTCTCGTGAAGAATGCTGTG
AAGACGTTTAAGGATATCGGGGTTTTCAAAGAGACCAAACAAAAGAGAGTGTCTGGGTTA
GAACTCAGCAACACTTTTCTACCTCAATGCAACCGGCAAAAACTCCTGGAATATATTCTG
AGTTTGGTGGTGCTGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 825 |
| Molecular Weight
| 93144.0 |
| Theoretical pI
| 8.0 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Glycerol-3-phosphate acyltransferase 1, mitochondrial
MDESALTLGTIDVSYLPNSSEYSIGRCKHATEEWGECGSRPTVFRSATLKWKESLMSRKR
PFVGRCCYSCTPQSWDKFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYVLFIQERDV
HKGMFATNVTENVLNSSRVQEAIAEVAGELNPDGSAQQQSKAVNKVKKKARKILQEMVAT
VSPAMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLIFLPVHRSHIDYLLLT
FILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDILYRALLHGHI
VELLRQQQFLEIFLEGTRSRSGKISCARAGLLSVVVDTLSTNTIPDILIIPGGISYDRII
EGHYNGEQLGKPKKNESLWSIARGVIRMLRKNYGCVKTDFAQPFSLKEYLESQSQKPVSA
PLSLEQALLPAILPSRPSGAADEGTDMSINESRNATDESRRRLIAHLAEHILFTASKSCA
IMSTHIVACLLLYRHRQGIGLFTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQFLG
NCITITHTSKNDEFFITPSTTIPSVFELNFYSNGVLHVFIMEAIIACSLYAVLKKRGPGG
PASPSLVSQEQLVHKAASLCYLLSNEGTISLPCQTFYQICHETVGRFIQYGILIVAEQDD
QEDISPGLAEQQWDKKLPEPLSWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQR
LLGPLLEAYSSAAVFIHNFGGPVPEPEFLQKLHKYLITRTERRVAVYAESATYCLVKNAV
KTFKDIGVFKETKQKRVSGLELSNTFLPQCNRQKLLEYILSLVVL
|
| External Links |
|---|
| GenBank ID Protein
| AAS79429.1 |
| UniProtKB/Swiss-Prot ID
| Q5GJ77 |
| UniProtKB/Swiss-Prot Entry Name
| GPAT1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AY515690 |
| GeneCard ID
| GPAM |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
