Showing Protein Adenylosuccinate lyase (BMDBP00935)
| Identification | |||||
|---|---|---|---|---|---|
| BMDB Protein ID | BMDBP00935 | ||||
| Secondary Accession Numbers | None | ||||
| Name | Adenylosuccinate lyase | ||||
| Synonyms | Not Available | ||||
| Gene Name | ADSL | ||||
| Protein Type | Enzyme | ||||
| Biological Properties | |||||
| General Function | Nucleotide transport and metabolism | ||||
| Specific Function | Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate. | ||||
| Pathways |
|
||||
| Reactions |
|
||||
| GO Classification | Not Available | ||||
| Cellular Location | Not Available | ||||
| Gene Properties | |||||
| Chromosome Location | 5 | ||||
| Locus | Not Available | ||||
| SNPs | ADSL | ||||
| Gene Sequence |
>1473 bp ATGGCCGCGGCGGGTGACCGTGGCGGGCGGGAGGCGGCCTGCGGGCATGACAGCTACCGT TCGCCGCTTGCTTCCCGTTATGCTAGCCCGGAGATGTGCTTCCTGTTTAGCGACAAGTAC AAATTCCGGACCTGGCGGCAGCTCTGGCTGTGGCTGGCGGAGGCCGAGCAGACACTGGGT TTGCCTATCACAGATGAACAAATCCAGGAGATGAAATCAAACCTGGACAACATTGACTTC AGGATGGCAGCTGAAGAGGAGAAGCAGTTGCGACATGATGTGATGGCCCACGTGCACACG TTTGCCCACTGCTGCCCCAAAGCCGCCAGCATTATCCATCTTGGCGCCACCTCCTGCTAT GTGGGAGACAATACGGACCTGATTATTCTCAGAAATGCATTTGACCTGCTTTTGCCAAAG CTTGCCAGGGTGATCTCTCGGCTTGCCGACTTTGCCAAGGAACAAGCCGATCTCCCCACC TTAGGTTTCACACATTTCCAGCCTGCTCAGCTGACCACAGTTGGGAAACGTTGCTGTCTC TGGATTCAGGATCTGTGCATGGATCTCCAGAACCTGAAGCGTGTCCGGGATGAGCTGCGC TTCCGAGGCGTGAAGGGTACCACTGGCACCCAGGCCAGCTTCCTGCAGCTCTTCGAAGGA GATGACCAAAAGGTAGAACAGCTTGACAAGATGGTGACAGAAAAGGCAGGATTCAAGAGG GCTTTTATCATCACAGGGCAGACCTATACACGAAAAGTAGATATTGAGGTGCTCTCTGTG CTGGCTAGCTTGGGGGCATCGGTGCACAAGATTTGTACCGACATACGACTCCTGGCAAAC CTCAAGGAGATGGAGGAGCCCTTTGAAAAACAGCAGATCGGCTCAAGTGCAATGCCATAC AAGCGGAACCCTATGCGCTCAGAGCGGTGCTGCAGCCTGGCCCGGCACCTGATGGCCCTT GTCATGGACCCCCTGCAGACGGCATCTGTGCAGTGGTTTGAACGCACACTCGATGACAGT GCCAACCGACGTATCTGTTTGGCGGAGGCGTTTCTCACTGCAGATACTGTACTGAATACG TTGCAGAACATTTCTGAAGGATTGGTGGTATACCCCAAAGTCATTGAGCGGCGCGTTCAG CAGGAGCTGCCTTTCATGGCCACAGAGAACATCATCATGGCCATGGTGAAAGCCGGGGGT AACCGCCAGGATTGCCGTGAGAAAATCAGAGTGCTCTCGCAGCAGGCAGCTGCCGTGGTC AAGCAGGAAGGGGGTGACAATGACCTCATCGAGCGCATCCAGGCCGATGCCTACTTCAGT CCAATCCACTCCCAGCTGGACCATTTGCTGGATCCTTCTTCTTTCACCGGCCGTGCGTCG CAGCAGGTACAGAGATTCTTAGAAGAGGAGGTGTGTCCCCTGTTAAAACCGTATGAAAGT GTGATGAAGGTGAAGGCAGAATTACGTCTGTAG |
||||
| Protein Properties | |||||
| Number of Residues | 490 | ||||
| Molecular Weight | 55484.0 | ||||
| Theoretical pI | 6.87 | ||||
| Pfam Domain Function | Not Available | ||||
| Signals |
|
||||
| Transmembrane Regions | Not Available | ||||
| Protein Sequence |
>Adenylosuccinate lyase MAAAGDRGGREAACGHDSYRSPLASRYASPEMCFLFSDKYKFRTWRQLWLWLAEAEQTLG LPITDEQIQEMKSNLDNIDFRMAAEEEKQLRHDVMAHVHTFAHCCPKAASIIHLGATSCY VGDNTDLIILRNAFDLLLPKLARVISRLADFAKEQADLPTLGFTHFQPAQLTTVGKRCCL WIQDLCMDLQNLKRVRDELRFRGVKGTTGTQASFLQLFEGDDQKVEQLDKMVTEKAGFKR AFIITGQTYTRKVDIEVLSVLASLGASVHKICTDIRLLANLKEMEEPFEKQQIGSSAMPY KRNPMRSERCCSLARHLMALVMDPLQTASVQWFERTLDDSANRRICLAEAFLTADTVLNT LQNISEGLVVYPKVIERRVQQELPFMATENIIMAMVKAGGNRQDCREKIRVLSQQAAAVV KQEGGDNDLIERIQADAYFSPIHSQLDHLLDPSSFTGRASQQVQRFLEEEVCPLLKPYES VMKVKAELRL |
||||
| External Links | |||||
| GenBank ID Protein | AAI33475.1 | ||||
| UniProtKB/Swiss-Prot ID | A3KN12 | ||||
| UniProtKB/Swiss-Prot Entry Name | PUR8_BOVIN | ||||
| PDB IDs | Not Available | ||||
| GenBank Gene ID | BC133474 | ||||
| GeneCard ID | ADSL | ||||
| GenAtlas ID | Not Available | ||||
| HGNC ID | Not Available | ||||
| References | |||||
| General References | Not Available | ||||