Showing Protein Platelet-activating factor acetylhydrolase (BMDBP00944)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00944 |
| Secondary Accession Numbers | None |
| Name | Platelet-activating factor acetylhydrolase |
| Synonyms | Not Available |
| Gene Name | PLA2G7 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in 1-alkyl-2-acetylglycerophosphocholine ester |
| Specific Function | Modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. Has a specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 23 |
| Locus | Not Available |
| SNPs | PLA2G7 |
| Gene Sequence |
>1335 bp ATGTTACCGTCCAAATTGCATGCGCTTTTCTGCCTCTGCACCTGCCTTGCACTGGTTTAT CCTTTTGACTGGCAAGACCTGAATCCAGTTGCCTATATTGAATCACCAGCATGGGTCAGT AAGATACAAGCTCTGATGGCTGCTGCAAACATTGGTCAATCTAAAATCCCCAGAGGAAAT GGATCTTATTCCGTCGGTTGTACAGACTTGATGTTTGATTACACTAATAAGGGCACCTTC TTGCGTTTGTATTATCCATCTCAAGATGATGATCACTCCGACACCCTTTGGATCCCAAAC AAAGAATATTTTTTGGGTCTTAGTAAATTTCTTGGAACACACTGGCTTGTGGGCAAAATT ATGGGCTTATTCTTCGGTTCAATGACAACTCCTGCAGCCTGGAATGCACATCTGAGGACT GGGGAAAAATACCCACTAATTATTTTTTCTCATGGTCTTGGAGCATTCAGGACGATTTAT TCTGCTATTGGCATTGATCTGGCATCCCACGGGTTTATAGTTGCTGCTGTAGAACACAGG GATGGCTCTGCATCCTCGACATACTATTTCAAGGACCAGTCTGCTGTAGAAATAGGCAAC AAGTCTTGGCTCTATCTCAGAACCCTGAAGCGAGGAGAGGAGGAGTTTCCTTTACGAAAT GAGCAGTTACGGCAACGAGCAAAGGAATGTTCTCAAGCTCTCAGTTTGATTCTGGACATT GATCACGGGAGGCCAGTGACGAATGTACTAGATTTAGAGTTTGATGTGGAACAGCTGAAG GACTCTATTGATAGGGATAAAATAGCCATTATTGGACATTCTTTTGGTGGAGCCACAGTT ATTCAGACTCTTAGTGAAGACCAGAGATTCAGGTGTGGCATTGCTCTGGATGCATGGATG TTTCCCGTGGGTGATGAAGTATATTCCAGAATTCCTCAACCCCTCTTTTTTATCAACTCG GAACGATTCCAATACCCTTCTAATATCATAAGAATGAAAAAATGCTTCTTACCTGATAGA GAACGAAAAATGATTACAATCAGGGGTTCGGTCCATCAGAATTTTGTTGACTTCACTTTT GCCACTAGCAAAATAATTGGCTACCTATTCACACTGAAAGGAGACATCGATTCCAATGTA GCCATCAGCCTTAGCAACAAAGCTTCCTTAGCGTTCTTACAAAAACATTTAGGACTTCAG AAAGATTTTGATCAGTGGGATTCTTTAGTTGAAGGCGAAGATCACAATCTTATTCCAGGG ACCAACATTAACACAACCAACCACCAAGCCATTCTGCAGAACTCCACAGGAATAGAGAGA CCAAATTTAGATTAA |
| Protein Properties | |
| Number of Residues | 444 |
| Molecular Weight | 50133.0 |
| Theoretical pI | 6.57 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Platelet-activating factor acetylhydrolase MLPSKLHALFCLCTCLALVYPFDWQDLNPVAYIESPAWVSKIQALMAAANIGQSKIPRGN GSYSVGCTDLMFDYTNKGTFLRLYYPSQDDDHSDTLWIPNKEYFLGLSKFLGTHWLVGKI MGLFFGSMTTPAAWNAHLRTGEKYPLIIFSHGLGAFRTIYSAIGIDLASHGFIVAAVEHR DGSASSTYYFKDQSAVEIGNKSWLYLRTLKRGEEEFPLRNEQLRQRAKECSQALSLILDI DHGRPVTNVLDLEFDVEQLKDSIDRDKIAIIGHSFGGATVIQTLSEDQRFRCGIALDAWM FPVGDEVYSRIPQPLFFINSERFQYPSNIIRMKKCFLPDRERKMITIRGSVHQNFVDFTF ATSKIIGYLFTLKGDIDSNVAISLSNKASLAFLQKHLGLQKDFDQWDSLVEGEDHNLIPG TNINTTNHQAILQNSTGIERPNLD |
| External Links | |
| GenBank ID Protein | AAC48483.1 |
| UniProtKB/Swiss-Prot ID | Q28017 |
| UniProtKB/Swiss-Prot Entry Name | PAFA_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | U34247 |
| GeneCard ID | PLA2G7 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |