Identification
BMDB Protein ID BMDBP00949
Secondary Accession Numbers None
Name Phosphomevalonate kinase
Synonyms Not Available
Gene Name PMVK
Protein Type Enzyme
Biological Properties
General Function Involved in ATP binding
Specific Function Not Available
Pathways
  • Isopentenyl diphosphate biosynthesis via mevalonate pathway
  • Isopentenyl diphosphate from (R)-mevalonate: step 2/3
  • Isoprenoid biosynthesis
  • Steroid Biosynthesis
Reactions
Adenosine triphosphate + Mevalonic acid-5P → ADP + 5-Diphosphomevalonic acid details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 3
Locus Not Available
SNPs PMVK
Gene Sequence
>579 bp
ATGGCCCCGCTGGGAGGCGTACCGGGGCTGGTGCTGCTGTTCAGCGGGAAGAGGAAATCC
GGGAAGGACTTCGTGACCGAGGCGCTTCAGAGCAGGCTAGGGGCTGATGTGTGTGCTATC
CTCCGGCTCTCCGGTCCACTCAAGGAGCAGTACGCTCAGGAGCACGGCTTGGACTTCCAG
AGACTTATGGATGCCAGCACCTACAAAGAGGCCTATCGGAGCGACATGATCCGCTGGGGC
GAGGAGAAGCGCCAGGCTGACCCAGGCTTCTTCTGCAGGAAGATTGTGGAGGGTGTCTGC
CAGCCTGTCTGGCTGGTGAGTGATACACGGAGGGTGTCTGACATCCAGTGGTTTCAGGAG
GCCTATGGGGCTGTGACACAGACGGTCCGTGTGGTGGCCACGGAGGAGAGCCGGCAGCAG
CGGGGCTGGGTGTTCACGCCAGGGGTGGACGACGCTGAGTCAGAGTGTGGCCTGGACAAC
TTCAGGACCTTCGATTGGGTCATTGAGAACCACGGGGATGAACAGCACCTGGAGGAGCAG
TTGGAGCACCTAATAGAATTTATCCGCTCCAGACTTTAG
Protein Properties
Number of Residues 192
Molecular Weight 21956.0
Theoretical pI 4.85
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence
>Phosphomevalonate kinase
MAPLGGVPGLVLLFSGKRKSGKDFVTEALQSRLGADVCAILRLSGPLKEQYAQEHGLDFQ
RLMDASTYKEAYRSDMIRWGEEKRQADPGFFCRKIVEGVCQPVWLVSDTRRVSDIQWFQE
AYGAVTQTVRVVATEESRQQRGWVFTPGVDDAESECGLDNFRTFDWVIENHGDEQHLEEQ
LEHLIEFIRSRL
GenBank ID Protein AAI12510.1
UniProtKB/Swiss-Prot ID Q2KIU2
UniProtKB/Swiss-Prot Entry Name PMVK_BOVIN
PDB IDs Not Available
GenBank Gene ID BC112509
GeneCard ID PMVK
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available