Showing Protein Ubiquitin-conjugating enzyme E2 E3 (BMDBP00966)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00966 |
| Secondary Accession Numbers | None |
| Name | Ubiquitin-conjugating enzyme E2 E3 |
| Synonyms | Not Available |
| Gene Name | UBE2E3 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in ATP binding |
| Specific Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest. |
| Pathways |
|
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 2 |
| Locus | Not Available |
| SNPs | UBE2E3 |
| Gene Sequence |
>624 bp ATGTCCAGTGATCGGCAGAGATCCGATGATGAGAGTCCCAGCACCAGCAGCGGTAGCTCA GATGCAGACCAGCGAGACCCAGCCGCTCCAGAGCCTGAAGAACAAGAAGAAAGAAAACCG TCTGCCACCCAGCAGAAGAAAAACACCAAACTCTCTAGCAAAACCACTGCTAAATTATCC ACTAGTGCTAAAAGAATTCAGAAGGAGCTAGCTGAAATAACCCTTGATCCTCCTCCTAAC TGCAGTGCTGGGCCTAAAGGAGATAACATTTATGAATGGAGATCGACTATACTTGGTCCA CCAGGTTCTGTATATGAAGGTGGTGTGTTTTTTCTGGATATCACATTTTCATCCGATTAT CCATTTAAGCCACCAAAGGTTACTTTCCGCACCAGAATCTATCACTGCAACATCAATAGT CAGGGAGTCATCTGCCTGGACATCCTTAAAGACAACTGGAGTCCTGCTTTGACTATTTCA AAGGTTTTGCTGTCAATTTGTTCTCTTTTGACAGACTGCAACCCTGCGGATCCTCTGGTT GGAAGCATAGCCACTCAGTATTTGACCAACAGAGCAGAACATGACAGGATAGCCAGACAG TGGACCAAGCGATACGCAACATAA |
| Protein Properties | |
| Number of Residues | 207 |
| Molecular Weight | 22913.0 |
| Theoretical pI | 7.25 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Ubiquitin-conjugating enzyme E2 E3 MSSDRQRSDDESPSTSSGSSDADQRDPAAPEPEEQEERKPSATQQKKNTKLSSKTTAKLS TSAKRIQKELAEITLDPPPNCSAGPKGDNIYEWRSTILGPPGSVYEGGVFFLDITFSSDY PFKPPKVTFRTRIYHCNINSQGVICLDILKDNWSPALTISKVLLSICSLLTDCNPADPLV GSIATQYLTNRAEHDRIARQWTKRYAT |
| External Links | |
| GenBank ID Protein | AAI11219.1 |
| UniProtKB/Swiss-Prot ID | Q2T9X7 |
| UniProtKB/Swiss-Prot Entry Name | UB2E3_BOVIN |
| PDB IDs | |
| GenBank Gene ID | BC111218 |
| GeneCard ID | UBE2E3 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |