Showing Protein NEDD8-conjugating enzyme UBE2F (BMDBP00968)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00968 |
| Secondary Accession Numbers | None |
| Name | NEDD8-conjugating enzyme UBE2F |
| Synonyms | Not Available |
| Gene Name | UBE2F |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in ATP binding |
| Specific Function | Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5. |
| Pathways |
|
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 3 |
| Locus | Not Available |
| SNPs | UBE2F |
| Gene Sequence |
>558 bp ATGCTGACGCTGGCAAGCAAGCTGAAGCGGGATGATGGTCTCAAAGGGTCCCGGGCGTCA GCCACAGCCTCTGACTCCACTCGGCGGGTGTCTGTGAGGGACAGGCTGCTTGTTAAAGAG GTTGCAGAACTTGAAGCTAATTTACCTTGTACGTGTAAAGTGCATTTTCCTGATCCAAAC AAGCTTCATTGCTTTCAGCTAACTGTCACCCCAGATGAGGGTTACTACCAGGGTGGAAAA TTTCAGTTTGAAACTGAAGTTCCTGACGCATACAACATGGTGCCTCCCAAAGTGAAATGC TTGACCAGGATCTGGCACCCCAACATCACCGAGACTGGTGAGATATGTCTCAGCTTACTG AGAGAACACTCGATCGACGGCACCGGCTGGGCCCCCACAAGGACGCTGAAGGATGTTGTT TGGGGATTAAACTCTTTGTTTACTGATCTGTTGAATTTTGATGATCCACTGAATATTGAA GCTGCGGAACATCATTTGCGAGACAAGGAGGACTTCCGGAATAAAGTGGAGGACTACATT AAGCGCTACGCCAGATGA |
| Protein Properties | |
| Number of Residues | 185 |
| Molecular Weight | 21133.0 |
| Theoretical pI | 6.78 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>NEDD8-conjugating enzyme UBE2F MLTLASKLKRDDGLKGSRASATASDSTRRVSVRDRLLVKEVAELEANLPCTCKVHFPDPN KLHCFQLTVTPDEGYYQGGKFQFETEVPDAYNMVPPKVKCLTRIWHPNITETGEICLSLL REHSIDGTGWAPTRTLKDVVWGLNSLFTDLLNFDDPLNIEAAEHHLRDKEDFRNKVEDYI KRYAR |
| External Links | |
| GenBank ID Protein | AAI14676.1 |
| UniProtKB/Swiss-Prot ID | Q1RMW1 |
| UniProtKB/Swiss-Prot Entry Name | UBE2F_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC114675 |
| GeneCard ID | UBE2F |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |