Showing Protein Ubiquitin-conjugating enzyme E2 H (BMDBP00973)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP00973 |
| Secondary Accession Numbers | None |
| Name | Ubiquitin-conjugating enzyme E2 H |
| Synonyms | Not Available |
| Gene Name | UBE2H |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in ATP binding |
| Specific Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. E2 ubiquitin conjugating enzyme that transfers ubiquitin to MAEA, a core component of the CTLH E3 ubiquitin-protein ligase complex. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Capable, in vitro, to ubiquitinate histone H2A. |
| Pathways |
|
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 4 |
| Locus | Not Available |
| SNPs | UBE2H |
| Gene Sequence |
>552 bp ATGTCATCCCCTAGTCCGGGCAAGAGGCGGATGGACACGGACGTGGTCAAGCTTATTGAG AGTAAGCATGAGGTTACTATCCTAGGAGGACTCAATGAATTTGTAGTGAAGTTTTATGGA CCACAAGGAACACCGTATGAAGGCGGAGTATGGAAAGTTAGAGTGGATCTTCCTGATAAA TACCCTTTCAAATCTCCTTCTATAGGATTCATGAATAAAATTTTCCATCCCAACATTGAT GAAGCGTCAGGAACTGTGTGTCTAGATGTAATTAATCAAACTTGGACAGCTCTCTATGAT CTTACCAATATATTTGAGTCCTTCCTGCCCCAGTTGTTGGCCTATCCCAACCCCATAGAT CCTCTCAATGGTGACGCTGCAGCTATGTACCTCCATCGACCAGAAGAATACAAGCAGAAA ATTAAAGAGTACATCCAGAAATATGCAACGGAGGAGGCACTGAAAGAGCAGGAAGAGGGC ACTGGAGACAGCTCATCGGAGAGTTCTATGTCTGACTTTTCGGAAGACGAGGCCCAGGAT ATGGAGTTGTAG |
| Protein Properties | |
| Number of Residues | 183 |
| Molecular Weight | 20655.0 |
| Theoretical pI | 4.29 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Ubiquitin-conjugating enzyme E2 H MSSPSPGKRRMDTDVVKLIESKHEVTILGGLNEFVVKFYGPQGTPYEGGVWKVRVDLPDK YPFKSPSIGFMNKIFHPNIDEASGTVCLDVINQTWTALYDLTNIFESFLPQLLAYPNPID PLNGDAAAMYLHRPEEYKQKIKEYIQKYATEEALKEQEEGTGDSSSESSMSDFSEDEAQD MEL |
| External Links | |
| GenBank ID Protein | AAI09503.1 |
| UniProtKB/Swiss-Prot ID | Q32LN1 |
| UniProtKB/Swiss-Prot Entry Name | UBE2H_BOVIN |
| PDB IDs | |
| GenBank Gene ID | BC109502 |
| GeneCard ID | UBE2H |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |