Identification |
BMDB Protein ID
| BMDBP00993 |
Secondary Accession Numbers
| None |
Name
| Prostaglandin F synthase 1 |
Synonyms
|
Not Available
|
Gene Name
| Not Available |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in prostaglandin-F synthase activity |
Specific Function
| Catalyzes the reduction of PGD(2) and PGH(2) to PGF(2 alpha) and a stereoisomer, respectively. It has a broad substrate specificity and reduces also other carbonyl compounds. |
Pathways
|
- Lipid metabolism
- Prostaglandin biosynthesis
|
Reactions
| Not Available |
GO Classification
|
Not Available
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| 13 |
Locus
| Not Available |
SNPs
| Not Available |
Gene Sequence
|
>972 bp
REAMOFBAMHISITE.CAAACAATGGATCCCAAAAGTCAGAGGGTGAAGCTTAATGATGG
CCACTTCATTCCTGTCCTGGGATTTGGAACCTATGCACCTGAGGAGGTTCCTAAGAGTGA
AGCCCTGGAGGCCACCAAATTTGCTATAGAGGTTGGGTTCCGCCATGTGGACAGTGCTCA
TTTGTATCAAAATGAGGAGCAGGTTGGCCAGGCCATTCGAAGCAAGATTGCAGATGGCAC
TGTGAAGAGAGAAGACATATTCTACACTTCAAAGCTTTGGTGCAATTCCCTTCAACCAGA
GTTGGTCCGACCAGCCTTGGAAAAGTCATTGCAAAATCTTCAACTGGACTATGTCGATCT
CTATATTATTCATTCTCCAGTGTCTCTGAAGCCAGGGAATAAATTTGTTCCAAAAGATGA
AAGTGGAAAACTGATATTTGACTCGGTGGATCTCTGTCACACGTGGGAGGCCCTGGAGAA
GTGTAAGGACGCAGGGCTGACCAAGTCCATTGGGGTGTCCAACTTCAACCACAAGCAGCT
GGAGAAGATCCTGAACAAGCCGGGGCTCAAGTACAAGCCCGTCTGCAACCAGGTGGAATG
TCACCCTTACCTCAACCAGAGCAAACTGTTAGAGTTCTGCAAGTCACATGATATTGTCCT
AGTTGCTTATGCTGCTCTGGGAGCCCAACTATTGTCAGAATGGGTGAACTCAAACAACCC
CGTTCTCTTGGAGGACCCGGTTCTTTGTGCCATTGCCAAAAAGCACAAGCAAACCCCAGC
TCTGGTTGCCCTTCGCTACCAGGTACAACGTGGAGTTGTGGTTCTGGCCAAGAGTTTCAA
CAAGAAGAGGATCAAAGAGAATATGCAGGTGTTTGACTTTGAACTGACTCCGGAAGATAT
GAAAGCAATCGATGGCCTCAATCGTAATATAAGATACTATGATTTTCAAAAGGGTATTGG
TCACCCTGAGTA
|
Protein Properties |
Number of Residues
| 323 |
Molecular Weight
| 36720.0 |
Theoretical pI
| 7.55 |
Pfam Domain Function
|
Not Available |
Signals
|
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Prostaglandin F synthase 1
MDPKSQRVKLNDGHFIPVLGFGTYAPEEVPKSEALEATKFAIEVGFRHVDSAHLYQNEEQ
VGQAIRSKIADGTVKREDIFYTSKLWCNSLQPELVRPALEKSLQNLQLDYVDLYIIHSPV
SLKPGNKFVPKDESGKLIFDSVDLCHTWEALEKCKDAGLTKSIGVSNFNHKQLEKILNKP
GLKYKPVCNQVECHPYLNQSKLLEFCKSHDIVLVAYAALGAQLLSEWVNSNNPVLLEDPV
LCAIAKKHKQTPALVALRYQVQRGVVVLAKSFNKKRIKENMQVFDFELTPEDMKAIDGLN
RNIRYYDFQKGIGHPEYPFSEEY
|
External Links |
GenBank ID Protein
| AAA30694.1 |
UniProtKB/Swiss-Prot ID
| P05980 |
UniProtKB/Swiss-Prot Entry Name
| PGFS1_BOVIN |
PDB IDs
|
Not Available |
GenBank Gene ID
| J03570 |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| Not Available |