Showing Protein Protein tyrosine phosphatase type IVA 3 (BMDBP01006)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01006 |
| Secondary Accession Numbers | None |
| Name | Protein tyrosine phosphatase type IVA 3 |
| Synonyms | Not Available |
| Gene Name | PTP4A3 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Signal transduction mechanisms |
| Specific Function | Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 14 |
| Locus | Not Available |
| SNPs | PTP4A3 |
| Gene Sequence |
>522 bp ATGGCGCGGATGAACCGGCCGGCCCCTGTGGAGGTCAGCTACAAGAACATGCGCTTCCTC ATCACGCACAACCCCACCAATGCCACCCTCAGCAGCTTCATCGAGGACCTGAAGAAGTAC GGGGCCACCACCGTGGTGCGCGTGTGTGAGGTGACCTACGACAAGGCCCCGCTGGAGAAG GACGGCATCACGGTTGTGGACTGGCCGTTTGATGATGGGGCACCCCCGCCCGGCAAAGTG GTGGAGGACTGGCTGAGCCTGCTGAAGAACAAGTTCTGTGATGACCCCGGCAGCTGCGTG GCTGTGCACTGCGTGGCTGGCCTGGGGCGGGCTCCCGTCCTCGTGGCGCTGGCCCTCATC GAGAGCGGGATGAAGTATGAGGACGCCATCCAGTTCATCCGACAGAAGCGGCGCGGAGCC ATCAACAGCAAACAGCTCACCTACCTGGAAAAATACCGGCCGAAGCAGAGACTGCGGTTC AAGGACCCCCACGCGCACAAGACCAAGTGCTGCATCATGTAG |
| Protein Properties | |
| Number of Residues | 173 |
| Molecular Weight | 19511.0 |
| Theoretical pI | 9.44 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Protein tyrosine phosphatase type IVA 3 MARMNRPAPVEVSYKNMRFLITHNPTNATLSSFIEDLKKYGATTVVRVCEVTYDKAPLEK DGITVVDWPFDDGAPPPGKVVEDWLSLLKNKFCDDPGSCVAVHCVAGLGRAPVLVALALI ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHAHKTKCCIM |
| External Links | |
| GenBank ID Protein | AAI33387.1 |
| UniProtKB/Swiss-Prot ID | A2VDT1 |
| UniProtKB/Swiss-Prot Entry Name | TP4A3_BOVIN |
| PDB IDs | |
| GenBank Gene ID | BC133386 |
| GeneCard ID | PTP4A3 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |