| Identification |
|---|
| BMDB Protein ID
| BMDBP01006 |
| Secondary Accession Numbers
| None |
| Name
| Protein tyrosine phosphatase type IVA 3 |
| Synonyms
|
Not Available
|
| Gene Name
| PTP4A3 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Signal transduction mechanisms |
| Specific Function
| Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 14 |
| Locus
| Not Available |
| SNPs
| PTP4A3 |
| Gene Sequence
|
>522 bp
ATGGCGCGGATGAACCGGCCGGCCCCTGTGGAGGTCAGCTACAAGAACATGCGCTTCCTC
ATCACGCACAACCCCACCAATGCCACCCTCAGCAGCTTCATCGAGGACCTGAAGAAGTAC
GGGGCCACCACCGTGGTGCGCGTGTGTGAGGTGACCTACGACAAGGCCCCGCTGGAGAAG
GACGGCATCACGGTTGTGGACTGGCCGTTTGATGATGGGGCACCCCCGCCCGGCAAAGTG
GTGGAGGACTGGCTGAGCCTGCTGAAGAACAAGTTCTGTGATGACCCCGGCAGCTGCGTG
GCTGTGCACTGCGTGGCTGGCCTGGGGCGGGCTCCCGTCCTCGTGGCGCTGGCCCTCATC
GAGAGCGGGATGAAGTATGAGGACGCCATCCAGTTCATCCGACAGAAGCGGCGCGGAGCC
ATCAACAGCAAACAGCTCACCTACCTGGAAAAATACCGGCCGAAGCAGAGACTGCGGTTC
AAGGACCCCCACGCGCACAAGACCAAGTGCTGCATCATGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 173 |
| Molecular Weight
| 19511.0 |
| Theoretical pI
| 9.44 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Protein tyrosine phosphatase type IVA 3
MARMNRPAPVEVSYKNMRFLITHNPTNATLSSFIEDLKKYGATTVVRVCEVTYDKAPLEK
DGITVVDWPFDDGAPPPGKVVEDWLSLLKNKFCDDPGSCVAVHCVAGLGRAPVLVALALI
ESGMKYEDAIQFIRQKRRGAINSKQLTYLEKYRPKQRLRFKDPHAHKTKCCIM
|
| External Links |
|---|
| GenBank ID Protein
| AAI33387.1 |
| UniProtKB/Swiss-Prot ID
| A2VDT1 |
| UniProtKB/Swiss-Prot Entry Name
| TP4A3_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| BC133386 |
| GeneCard ID
| PTP4A3 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
