Showing Protein 3-hydroxybutyrate dehydrogenase type 2 (BMDBP01009)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01009 |
| Secondary Accession Numbers | None |
| Name | 3-hydroxybutyrate dehydrogenase type 2 |
| Synonyms | Not Available |
| Gene Name | BDH2 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Lipid transport and metabolism |
| Specific Function | Dehydrogenase that mediates the formation of 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron assimilation and homeostasis. Plays a role in susceptibility to bacterial infection by providing an assimilable source of iron that is exploited by pathogenic bacteria (By similarity). Also acts as a 3-hydroxybutyrate dehydrogenase (By similarity). |
| Pathways |
|
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 6 |
| Locus | Not Available |
| SNPs | BDH2 |
| Gene Sequence |
>738 bp ATGGGTCGACTTGATGGGAAGGTCATTGTCCTGACGGCTGCTGCTCAGGGGATCGGCCGG GCAGCCGCATTGGCTTTTGCAAAAGAAGGTGCCAAAGTCATAGCCACCGATATCAATGAC TCCAAACTTCAGGAACTGGATAAGTACCCAGGTATTCACACTCGGGTCCTTGATGTCACA AAGAAGAAGCAAATTGACCAGTTTGCCAATGACATTGAGAGACTTGATGTTCTCTTTAAC GTTGCTGGTTTCGTCCATCACGGAACCATCCTGGACTGTGAAGAGACAGACTGGGACTTC TCGATGAACCTCAACGTCCGCAGCATGTACCTGATGATCAAGGCTTTTCTTCCTAAGATG ATGGCTCAGAAATCTGGCAACATTATCAACATGTCCTCTGTGGCTTCCAGCATCAAAGGC GTTGTGAACAGGTGCGTGTACAGCACAACCAAGGCGGCCGTGATCGGCCTCACAAAGTCC GTGGCTGCAGACTTCATCCAGCAGGGTATCCGGTGCAACTGTGTGTGTCCAGGAACAGTT GATACCCCATCTCTGCAAGAAAGAATACAAGCCAGACCAAATCCTGAAGAGGCACTGAGC GATTTCCTAAAGAGACAGAAAACAGGAAGATTTGCAACTGCAGAAGAAGTAGCCCTGCTC TGCGTGTACTTGGCCTCTGATGAATCTGCCTACATCACGGGGAATCCTGTCATCATTGAT GGAGGCTGGAGTTTGTGA |
| Protein Properties | |
| Number of Residues | 245 |
| Molecular Weight | 26662.0 |
| Theoretical pI | 7.3 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>3-hydroxybutyrate dehydrogenase type 2 MGRLDGKVIVLTAAAQGIGRAAALAFAKEGAKVIATDINDSKLQELDKYPGIHTRVLDVT KKKQIDQFANDIERLDVLFNVAGFVHHGTILDCEETDWDFSMNLNVRSMYLMIKAFLPKM MAQKSGNIINMSSVASSIKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVCPGTV DTPSLQERIQARPNPEEALSDFLKRQKTGRFATAEEVALLCVYLASDESAYITGNPVIID GGWSL |
| External Links | |
| GenBank ID Protein | AAI02568.1 |
| UniProtKB/Swiss-Prot ID | Q3T046 |
| UniProtKB/Swiss-Prot Entry Name | BDH2_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC102567 |
| GeneCard ID | BDH2 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |