Identification
BMDB Protein ID BMDBP01025
Secondary Accession Numbers
  • BMDBP03034
Name 2-aminomuconic semialdehyde dehydrogenase
Synonyms Not Available
Gene Name ALDH8A1
Protein Type Enzyme
Biological Properties
General Function Energy production and conversion
Specific Function Catalyzes the NAD-dependent oxidation of 2-aminomuconic semialdehyde of the kynurenine metabolic pathway in L-tryptophan degradation.
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 9
Locus Not Available
SNPs ALDH8A1
Gene Sequence
>1464 bp
ATGGCTGGAAGAGGAGGTCTTTTGATGCTGGAAAACTTCATAGGTGGAAAATTTTTACCT
TGTAGCTCATACCTAGATTCCTATGATCCCTCCACAGGGGAAGTGTACTGCCATGTGCCA
AACAGTGGGAAAGAAGAGGTCGAAGCCGCGGTGGAGGCTGCCAGAGCAGCTTTTCCGGGC
TGGTCCTCCCGGAGCCCCCAGGAGCGCTCACAGGTGCTGCAGCGGCTGGCGGACTTGCTG
GAACAGTCCCTGGAGGAGCTGGCCCAGGCTGAGTCCAAGGACCAAGGGAAAACCATAACC
CTGGCGAGAACCATGGACATTCCCCGGGCTGTGCACAACTTCCGGTTCTTCGCCTCCTCC
ATCCTGCACCACACGTCTGAATGCACACAGATGGACCACCTGGGCTGTCTGCACTACACA
GTGCGGGCCCCCGTGGGCATCGCTGCTCTGATCAGTCCCTGGAATCTGCCCCTCTATCTG
CTGACCTGGAAGATCGCGCCAGCGATCGCTGCTGGCAACACAGTGATAGCTAAGCCCAGC
GAGCTGACTTCCGTGACCGCGTGGATGATGTGCAGACTCCTGGAGAAAGCAGGTGTTCCC
CCAGGTGTGGTAAATATTGTGTTTGGAACGGGGCCCAGGGTAGGCGAGGCCCTGGTGTCC
CACCCAGAGGTGCCCCTCATCTCCTTCACTGGGAGCCAGCCCACCGCCGAGCGCATCATG
CAGCTGAGCGCCCCCCACTGCAAGAAGCTCTCGCTGGAGCTGGGGGGCAAGAATCCTGCC
GTCATCTTTGAAGATGCCAACCTGGCCGAGTGCATTCCGACAACTGTCAGGTCCAGCTTT
GCCAACCAGGGTGAAATCTGCCTCTGTACCAGCAGAATCTTTGTCCAGAGGAGCATCTAT
AGTGAATTTTTAAAGAGGTTTGTAGAGGCGGCCAGAATGTGGAAAGTTGGTATTCCTTCT
GATCCATCGGCTGACATGGGCGCTCTGATCAGTAAAGCTCATCTGGAGAAAGTCAGAAGT
TACATCAAGAAAGCTCGCATGGAAGGGGCCCAAATTCTGTGTGGTGAGGGAGTGGATAAG
TTGAACCTTCCCCCCAGGAATCAGGCAGGGTACTTCATGCTTCCCACGGTGATAACAGAT
GTTAAGGATGAGTCCTGCTGCATGAAGGAAGAGATATTTGGTCCAGTGACGTGTGTCGTC
CCCTTTGATAGTGAAGAGGAAGTGATTCAAAGAGCCAATAATGTTAAATATGGACTGGCT
GCTACCGTGTGGTCAGGCAACGTGGGGCGTGTCCACCGGGTGGCCAAGAAGTTACAGTCA
GGCTTGGTCTGGACCAACTGCTGGCTTATTAGAGAGCTGAACCTACCTTTCGGGGGGATG
AAGAGTTCTGGGGTGGGCAGAGAAGGAGCCAAAGACTCTTACGAATTCTTCACTGAAGTC
AAAACCATCACTGTTAAACACTGA
Protein Properties
Number of Residues 487
Molecular Weight 53363.0
Theoretical pI 7.62
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 227-247
Protein Sequence
>Aldehyde dehydrogenase family 8 member A1
MAGRGGLLMLENFIGGKFLPCSSYLDSYDPSTGEVYCHVPNSGKEEIEAAVEAARAAFPG
WSSRSPQERSQVLQRLADLLEQSLEELAQAESKDQGKTITLARTMDIPRAVHNFRFFASS
ILHHTSECTQMDHLGCLHYTVRAPVGIAALISPWNLPLYLLTWKIAPAIAAGNTVIAKPS
ELTSVTAWMMCRLLEKAGVPPGVVNIVFGTGPRVGEALVSHPEVPLISFTGSQPTAERIM
QLSAPHCKKLSLELGGKNPAVIFEDANLAECIPTTVRSSFANQGEICLCTSRIFVQRSIY
SEFLKRFVEAARMWKVGIPSDPSADMGALISKAHLEKVRSYIKKARMEGAQILCGEGVDK
LNLPPRNQAGYFMLPTVITDVKDESCCMKEEIFGPVTCVVPFDSEEEVIQRANNVKYGLA
ATVWSGNVGRVHRVAKKLQSGLVWTNCWLIRELNLPFGGMKSSGVGREGAKDSYEFFTEV
KTITVKH
GenBank ID Protein ABM06132.1
UniProtKB/Swiss-Prot ID Q0P5F9
UniProtKB/Swiss-Prot Entry Name AL8A1_BOVIN
PDB IDs Not Available
GenBank Gene ID BT029881
GeneCard ID ALDH8A1
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available