Showing Protein Disintegrin and metalloproteinase domain-containing protein 2 (BMDBP01043)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01043 |
| Secondary Accession Numbers | None |
| Name | Disintegrin and metalloproteinase domain-containing protein 2 |
| Synonyms | Not Available |
| Gene Name | ADAM2 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in metalloendopeptidase activity |
| Specific Function | Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. Could have a direct role in sperm-zona binding or migration of sperm from the uterus into the oviduct. Interactions with egg membrane could be mediated via binding between its disintegrin-like domain to one or more integrins receptors on the egg. This is a non catalytic metalloprotease-like protein (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 27 |
| Locus | Not Available |
| SNPs | ADAM2 |
| Gene Sequence | Not Available |
| Protein Properties | |
| Number of Residues | 745 |
| Molecular Weight | 83150.0 |
| Theoretical pI | 5.11 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Disintegrin and metalloproteinase domain-containing protein 2 MLCLLFLLLGLTGLQTDDNSERLRVQFTVPEKIRSTSSGGVETHVSYIILIEGKTYTVNL MQKAFLPHNFRVYGYSGTGSMKPLEHEFQNFCYYQGYIEGYPNSMAIISTCTGLRGLLQF ENVSYGIEPLEPSIGFEHMVYQIKPRDSSSSVYTEREIELREKPYKIQNVEPLPDFSQYI EMHIVVEKDLYNHMGADTTVVIQKIFQLTGLTNAIFTSLNITVILSSLELWIDENKIPVT GDANELLHRFVKWKRSYLVLRPHDMAFLLVYREKSNYIGATFQGRMCDKHYGGGVALHSS TISLESLAVIIAQLLSLSMGIPYDDINKCHCPGDVCIMNPAAVHSSGVKLFSNCSVEDFL RFISKPKSQCLQNQPRLDPTYKSAVCGNGKVEEGEQCDCGNKKACDALPDTCCVADTCRF QPGSACDTGLCCESCAFIPKGHICRGSTDECDLHEYCNGSSAACQEDVYVQDGHPCGQNQ WLCISGICVDGIKQCFDIFGEGTSYAPAECFQRLNSMNDLSGNCGVTPTGFTPCTSENVR CGKLLCTYDKREVISVENASVMYSNINGKICIGLHYEYGNEDEGMMWVKDGTVCGESKIC QNKQCVDSSFLNYDCNPEKCNNQGVCNNKKHCHCNPSYLPPNCEHSAPGWEGGSIDSGNF PPSEPPTGGPAFTDVGTTPLAESRYIENVYRSKPTRWPFFLFIPFFIILCVLIATLVKVY FQRKKWRTEDYTSDEQLESESEPKD |
| External Links | |
| GenBank ID Protein | AAC62753.1 |
| UniProtKB/Swiss-Prot ID | O77780 |
| UniProtKB/Swiss-Prot Entry Name | ADAM2_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | AF086808 |
| GeneCard ID | ADAM2 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |