Identification
BMDB Protein ID BMDBP01078
Secondary Accession Numbers None
Name Leukotriene C4 synthase
Synonyms Not Available
Gene Name LTC4S
Protein Type Enzyme
Biological Properties
General Function Involved in enzyme activator activity
Specific Function Catalyzes the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4.
Pathways
  • Arachidonic Acid Metabolism
Reactions
Leukotriene A4 + Glutathione → Leukotriene C4 details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 7
Locus Not Available
SNPs LTC4S
Gene Sequence
>402 bp
ATGAAGGACGAGGTAGCTCTTCTGGCCTCTGTCACCCTCCTGGGCGTCCTGCTGCAAGCC
TACTTCTCTCTGCAGGTGATCTCGGCGCGCAGGGCCTTCCGCGTTTCGCCGCCGCTCACC
ACTGGCCCGCCGGAGTTCGAGCGCATCTACCGAGCCCAAGTGAACTGCAGCGAGTACTTC
CCGCTGTTCCTCGCCATGCTCTGGGTGGCCGGCATCTTCTTTCACGAAGGTGCGGCAGCA
CTGTGTGGTCTGGTCTACCTGTTCGCACGCCTACGCTACTTCCAGGGCTACGCGCGCTCT
GCGCAGCAGAGGCTGGCCCCGCTGTACGCGAGCGCGCGCGCGCTCTGGCTTCTCGTGGCC
CTGGCGGCCCTTGGCCTGCTCGCCCACTTCCTCCCGGCCTAG
Protein Properties
Number of Residues 150
Molecular Weight 16701.0
Theoretical pI 10.34
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions
  • 7-27
  • 49-69
  • 74-94
  • 105-124
Protein Sequence
>Leukotriene C4 synthase
MKDEVALLASVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERIYRAQVNCSEYF
PLFLAMLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQQRLAPLYASARALWLLVA
LAALGLLAHFLPAELRAALLGQLRKLLLRS
GenBank ID Protein AAI11677.1
UniProtKB/Swiss-Prot ID Q2NKS0
UniProtKB/Swiss-Prot Entry Name LTC4S_BOVIN
PDB IDs Not Available
GenBank Gene ID BC111676
GeneCard ID LTC4S
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available