| Identification |
|---|
| BMDB Protein ID
| BMDBP01086 |
| Secondary Accession Numbers
| None |
| Name
| Ribonucleoside-diphosphate reductase |
| Synonyms
|
Not Available
|
| Gene Name
| RRM1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Nucleotide transport and metabolism |
| Specific Function
| Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. |
| Pathways
|
- DNA replication
- Genetic information processing
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 15 |
| Locus
| Not Available |
| SNPs
| RRM1 |
| Gene Sequence
|
>2376 bp
ATGCATGTGATCAAGCGAGATGGCCGCCAAGAGCGAGTTATGTTCGACAAAATTACATCC
CGAATCCAGAAGCTTTGTTATGGGCTCAATATGGACTTTGTTGATCCTGCTCAGATCACT
ATGAAGGTAATCCAAGGCTTATACAGTGGGGTCACTACTGTGGAACTGGATACTTTGGCT
GCTGAGACAGCCGCAACCTTGACTACTAAGCACCCTGACTATGCCATCCTGGCAGCAAGG
ATTGCCGTCTCTAACTTGCACAAAGAAACCAAGAAAGTATTCAGTGATGTAATGGAAGAC
CTCTTCAACTATATAAACCCACACAATGGCAAACACTCTCCCATGGTGGCCAAGTCAACA
TTGGATATTGTTTTGGCAAATAAAGATCGCCTGAATTCTGCAATTATCTATGACCGAGAT
TTCTCTTATAATTACTTTGGCTTTAAGACACTGGAGCGATCCTATTTGTTGAAGATCAAT
GGGAAGGTGGCTGAAAGACCACAACACATGTTGATGAGGGTATCTGTGGGGATTCACAAA
GAAGATATTGATGCTGCTATTGAAACCTACAACCTTCTTTCTGAGAAGTGGTTTACCCAT
GCCTCTCCCACTCTCTTCAATGCTGGTACCAACCGCCCACAACTTTCTAGCTGTTTCCTT
CTGAGTATGAAAGATGATAGCATTGAAGGCATTTATGACACTCTAAAGCAGTGTGCATTG
ATTTCCAAGTCCGCTGGTGGAATTGGTGTTGCTGTGAGTTGTATTCGAGCTACTGGCAGC
TACATTGCTGGGACTAATGGCAATTCCAATGGTCTTGTACCGATGCTGAGAGTATATAAC
AACACAGCTCGATATGTGGATCAAGGTGGAAACAAGCGACCTGGGGCATTTGCTATTTAC
CTGGAACCTTGGCATTTAGACATCTTTGAGTTCCTTGATTTAAAGAAGAACACAGGAAAG
GAAGAGCAGCGTGCCAGGGACCTTTTCTTTGCCCTTTGGATTCCAGATCTCTTCATGAAG
CGAGTGGAGACTAATCAGGACTGGTCTTTGATGTGTCCAAATGAATGTCCTGGTCTGGAT
GAGGTCTGGGGAGAAGAATTTGAGAAGCTATATGAAAGGTATGAGAAAGAAGGTCGTGTC
CGCAAAGTTATAAAAGCTCAGCAGCTTTGGTATGCCATCATTGAGTCTCAGACAGAGACA
GGTACCCCGTATATGCTCTACAAAGATTCCTGTAATCGGAAGAGCAACCAGCAGAACTTG
GGAACCATCAAATGCAGCAACCTGTGCACAGAAATAGTAGAGTATACCAGCAAAGATGAG
GTTGCAGTCTGTAACTTGGCTTCCCTGGCCCTGAATATGTATGTCACATCAGAACACACA
TATGACTTTACAAAGTTGGCTGAAGTCACCAAAGTCATTGTCCGAAACTTGAATAAAATT
ATTGATATTAACTACTACCCTGTCCCAGAGGCTAGCTTGTCGAATAAACTCCATCGCCCC
ATTGGAATTGGGGTACAAGGTCTGGCAGATGCTTTTATTCTGATGAGGTACCCTTTTGAG
AGTCCAGAGGCCCAATTATTGAATAAGCAGATCTTTGAAACCATTTATTATGGAGCCTTG
GAAGCCAGCTGTGACCTGGCCAAGGAGTATGGCCCATATGAAACCTATGAGGGCTCTCCA
GTCAGCAAAGGAATCCTTCAGTATGATATGTGGAATGTTACTCCTACAGACCTGTGGGAC
TGGAACCTTCTCAAGGAGAAGATTGCAAAGTATGGTGTAAGAAACAGTTTACTTATTGCC
CCGATGCCTACTGCTTCAACTGTTCAGATATTGGGAAATAATGAGTCAATTGAACCTTAT
ACCAGTAACATCTACACTCGCAGAGTCTTGTCAGGAGAATTTCAGATTGTAAATCCTCAC
TTACTGAAAGATCTTACTGAGCGGGGCTTGTGGAATGAAGAGATGAAAAATCAGATTATT
GCATGCAATGGGTCCATCCAGAGCATACCAGAAATTCCTGATGACCTGAAGCAGCTTTAT
AAGACTGTGTGGGAAATCTCTCAGAAAACCGTGCTCAAGATGGCCGCTGAGAGAGGCGCT
TTCATTGATCAAAGCCAGTCTTTGAACATACATATTGCTGAGCCTAACTATGGCAAACTC
ACTAGTATGCACTTCTACGGCTGGAAACAGGGTTTGAAGACTGGGATGTATTATTTAAGG
ACAAGACCAGCCGCTAATCCAATCCAGTTCACTCTAAATAAAGAAAAGCTGAAAGATAAG
GAAAAGGTATCGAAAGAAGAAGAGAAGGAGAGGAACACAGCAGCCATGGTGTGCTCTTTG
GAGAACAGAGATGAATGTCTGATGTGTGGGTCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 791 |
| Molecular Weight
| 90019.0 |
| Theoretical pI
| 6.74 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Ribonucleoside-diphosphate reductase
MHVIKRDGRQERVMFDKITSRIQKLCYGLNMDFVDPAQITMKVIQGLYSGVTTVELDTLA
AETAATLTTKHPDYAILAARIAVSNLHKETKKVFSDVMEDLFNYINPHNGKHSPMVAKST
LDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKINGKVAERPQHMLMRVSVGIHK
EDIDAAIETYNLLSEKWFTHASPTLFNAGTNRPQLSSCFLLSMKDDSIEGIYDTLKQCAL
ISKSAGGIGVAVSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQGGNKRPGAFAIY
LEPWHLDIFEFLDLKKNTGKEEQRARDLFFALWIPDLFMKRVETNQDWSLMCPNECPGLD
EVWGEEFEKLYERYEKEGRVRKVIKAQQLWYAIIESQTETGTPYMLYKDSCNRKSNQQNL
GTIKCSNLCTEIVEYTSKDEVAVCNLASLALNMYVTSEHTYDFTKLAEVTKVIVRNLNKI
IDINYYPVPEASLSNKLHRPIGIGVQGLADAFILMRYPFESPEAQLLNKQIFETIYYGAL
EASCDLAKEYGPYETYEGSPVSKGILQYDMWNVTPTDLWDWNLLKEKIAKYGVRNSLLIA
PMPTASTVQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWNEEMKNQII
ACNGSIQSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEPNYGKL
TSMHFYGWKQGLKTGMYYLRTRPAANPIQFTLNKEKLKDKEKVSKEEEKERNTAAMVCSL
ENRDECLMCGS
|
| External Links |
|---|
| GenBank ID Protein
| AAI09487.2 |
| UniProtKB/Swiss-Prot ID
| Q32LP1 |
| UniProtKB/Swiss-Prot Entry Name
| Q32LP1_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC109486 |
| GeneCard ID
| RRM1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
