Showing Protein Retinal guanylyl cyclase 2 (BMDBP01109)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01109 |
| Secondary Accession Numbers | None |
| Name | Retinal guanylyl cyclase 2 |
| Synonyms | Not Available |
| Gene Name | GUCY2F |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Signal transduction mechanisms |
| Specific Function | Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors (PubMed:9571173, PubMed:9175772). Plays an essential role in phototransduction, by mediating cGMP replenishment (PubMed:9571173, PubMed:9175772). May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | X |
| Locus | Not Available |
| SNPs | GUCY2F |
| Gene Sequence |
>3312 bp ATGTTCTTGGCACCCTGGCCTTTCTCCCACCTTATGCTCTGGTTCGTGACTCTGGGAAGA CAGCGAGGACAACATGGCCTTGCATCTTTCAAGCTCCTGTGGTGTTTGTGGCTCTTGGTC CTTATGTCTCTCCCACTACAGGTGTGGGCGCCACCCTACAAGATAGGGGTGGTTGGCCCT TGGACTTGTGATCCATTGTTCTCAAAGGCCCTGCCTGAGATTGCTGCTCAGTTAGCCACT GAGCGGATCAACAAGGACCCAGCCTTGGACCTGGGTCACTCTCTTGAATATGTGATTTTC AATGAAGACTGCCAGGCTTCCAGGGCTCTCTCCAGTTTCATTTCCCACCACCAGATGGCC TCAGGGTTTATTGGACCTGCCAACCCTGGCTACTGCGAGGCAGCCTCGCTCCTGGGAAAC AGCTGGGACAAAGGGATTTTCTCCTGGGCTTGCGTGAATTATGAATTAGACAGTAAAAAT AGCCACCCGACTTTTTCTCGGACCCTCCCTTCTCCCATCCGGGTGCTGCTAACTGTCATG AAATATTTCCAGTGGGCTCACGCTGGAGTCATTTCCTCAGATGAAGACATTTGGGTGCAC ACAGCCTATCGAGTTGCAAGTGCTCTTCGGAGCCGCGGCCTGCCAGTAGGGGTCGTCCTG ACCACAGGACAAGACAGCCAAAGCATCCAGAAAGCTCTCCAGCAGATTCGCCAGGCAGAT AGAATTCGCATAATCATCATGTGTATGCATTCGACTTTGATTGGGGGAGAGACTCAGACG CATCTCTTGGAATGGGCTCACGATCTGCAAATGACTGATGGCACCTATGTCTTTGTTCCC TATGACACCCTGCTCTACAGTTTACCTTATAAGCATACCCCCTACAAGGTTTTAAGGAAC AACCCAAAACTCCGGGAAGCCTATGATGCTGTGTTGACCATCACAGTAGAGTCCCAAGAA AAGACCTTCTATCAAGCCTTTGAGGAGGCAGCAGCTAGAGGTGAAATTCCTGAGAAGCTG GAGTCAGATCAAGTTTCGCCGTTGTTTGGAACCATCTACAATTCAATTTACTTTATCGCA CAAGCCATGAATAATGCTATGAAAGAAAATGGATGGGCTAGTGCTGCCAGCCTGGTTCAG CATTCCAGAAACGTGCAGTTCTATGGATTCAACCAGTTGATAAGGACAGATGCAAATGGA AATGGAATTTCAGAATATGTAATCCTGGACACCAACTGGAAAGAATGGGAACTCCATAGT ACCTACACTGTGGACATGGAAACGGAGCTGCTACGATTCGGAGAGACCCCTATTCACTTT CCTGGTGGCAGGCCCCCTCGAGCAGATGCACAATGCTGGTTTGCAGATGGGAGGATCTGC CAAGGAGGCATCAACCCTACTTTTGCTTTGATGGTCTGCCTTGCTTTGCTTATAGCCCTG CTGTCTATTAATGGATTTGCTTACTTTATAAGACATCGTATAAATAAAATCCAGTTGATT AAAGGACCCAACAGAATTCTACTGACTTTGGAGGATGTGACATTTATCAATCCCCACTTT GGCAGTAAGAGAGGAAGTCATGCCAGTGTAAGTTTCCAGATCACGTCGGAGGTCCAGAGT GGAAGGTCCCCAAGACTCTCCTTTTCTTCAGGGAGTCTAACTCCAGCTACCTGTGAAAAC TCCAACATAGCGATTTATGAGGGTGATTGGGTATGGCTGAAAAAATTCCCCTCAGGAAAT TTTGGAGACATTAAATCCGTCGAATCAAGTGCAAGTGACATATTTGAAATGATGAAGGAC CTGCGTCATGAGAATATTAACCCTTTGGTGGGCTTCTTCTATGATTCGGGGGTATTTGCC ATTGTGACAGAATTCTGTTCCCGAAGGAGCCTGGAAGACATACTGATGAATCAGGATGTG AAACTAGATTGGATGTTTAAATCATCACTCCTGCTGGATCTCATCAAGGGCATGAAGTAC TTACACCACAGAGAGTTTGCTCATGGGAGGCTGAAGTCTCGGAACTGTGTGGTGGATGGA CGTTTTGTACTCAAAGTGACAGATTATGGCTTTAATGACATCTTGGAAACGCTAAGACTC TCCCAAGAGGAACCTTCTGCAGAAGAGTTGCTGTGGACAGCCCCTGAACTGTTGAGAGCC CCGAGGGGCAGCAGGTTACGTTCTTTTGCAGGAGACGTCTATAGCTTTGCCATCATCATG CAGGAAGTGATGGTCCGGGGCACCCCATTCTGCATGATGGATCTACCTGCCAAAGAAATC ATAGAAAGAATTAAGAAGCCTCCTCCAGTGTACAGACCAGTGGTTCCTCCTGAGCATGCA CCCCCAGAATGTCTCCAGCTGATGAAGCAGTGCTGGGCTGAGGCTGCAGAACAACGACCA ACATTTGATGAAATATTTAACCAGTTTAAAACTTTCAATAAAGGGAAGAAGACTAATATT ATTGACTCTATGCTTCGGATGCTGGAGCAATATTCTAGCAACTTGGAAGATTTGATCCAG GAGCGAACTGAAGAGCTGGAAATTGAAAAACAGAAAACGGAAAAGCTCCTAACACAGATG CTCCCACCATCAGTTGCTGAATCTCTCAAAAAGGGCTGCACAGTCGAACCGGAGGGCTTT GACTTGGTCACCTTGTACTTCAGCGACATTGTGGGCTTCACTACCATCTCAGCCATGAGT GAGCCCATTGAGGTGGTGGATCTTCTCAATGACCTGTACACCCTCTTTGATGCCATCATT GGCAGTCATGATGTCTACAAGGTAGAGACTATTGGAGATGCTTACATGGTGGCCTCAGGC CTCCCAAAGAGGAATGGTATGAGGCATGCAGCTGAGATTGCAAACATGTCCCTAGACATC CTCAGCTCTGTGGGTACCTTCAAGATGCGGCACATGCCAGAGGTGCCGGTCCGGATTCGA ATAGGCCTGCACTCAGGGCCGGTTGTTGCTGGAGTGGTGGGCCTCACTATGCCCAGATAC TGCTTGTTTGGAGATACTGTGAACACGGCTTCTCGGATGGAATCAACAGGGTTACCTTAT CGCATTCATGTCAGTCATAGCACAGTGACAATTCTTCGAACCCTGGGTGAAGGCTATGAA GTGGAGCTTCGAGGAAGAACAGAGCTCAAGGGCAAAGGCACAGAAGAGACCTTCTGGCTG GTTGGGAAAAAGGGCTTCACGAAGCCCCTTCCTGTGCCCCCACCAGTGGGCAAAGATGGG CAAGTGGGCCATGGCCTTCAGTCAGTAGAGATTGCAGCCTTCCAAAGAAGAAAGCAGAAA AGCAGCTGGTGA |
| Protein Properties | |
| Number of Residues | 1103 |
| Molecular Weight | 124262.0 |
| Theoretical pI | 6.79 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions |
|
| Protein Sequence |
>Retinal guanylyl cyclase 2 MFLAPWPFSHLMLWFVTLGRQRGQHGLASFKLLWCLWLLVLMSLPLQVWAPPYKIGVVGP WTCDPLFSKALPEIAAQLATERINKDPALDLGHSLEYVIFNEDCQASRALSSFISHHQMA SGFIGPANPGYCEAASLLGNSWDKGIFSWACVNYELDSKNSHPTFSRTLPSPIRVLLTVM KYFQWAHAGVISSDEDIWVHTAYRVASALRSRGLPVGVVLTTGQDSQSIQKALQQIRQAD RIRIIIMCMHSTLIGGETQTHLLEWAHDLQMTDGTYVFVPYDTLLYSLPYKHTPYKVLRN NPKLREAYDAVLTITVESQEKTFYQAFEEAAARGEIPEKLESDQVSPLFGTIYNSIYFIA QAMNNAMKENGWASAASLVQHSRNVQFYGFNQLIRTDANGNGISEYVILDTNWKEWELHS TYTVDMETELLRFGETPIHFPGGRPPRADAQCWFADGRICQGGINPTFALMVCLALLIAL LSINGFAYFIRHRINKIQLIKGPNRILLTLEDVTFINPHFGSKRGSHASVSFQITSEVQS GRSPRLSFSSGSLTPATCENSNIAIYEGDWVWLKKFPSGNFGDIKSVESSASDIFEMMKD LRHENINPLVGFFYDSGVFAIVTEFCSRRSLEDILMNQDVKLDWMFKSSLLLDLIKGMKY LHHREFAHGRLKSRNCVVDGRFVLKVTDYGFNDILETLRLSQEEPSAEELLWTAPELLRA PRGSRLRSFAGDVYSFAIIMQEVMVRGTPFCMMDLPAKEIIERIKKPPPVYRPVVPPEHA PPECLQLMKQCWAEAAEQRPTFDEIFNQFKTFNKGKKTNIIDSMLRMLEQYSSNLEDLIQ ERTEELEIEKQKTEKLLTQMLPPSVAESLKKGCTVEPEGFDLVTLYFSDIVGFTTISAMS EPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPKRNGMRHAAEIANMSLDI LSSVGTFKMRHMPEVPVRIRIGLHSGPVVAGVVGLTMPRYCLFGDTVNTASRMESTGLPY RIHVSHSTVTILRTLGEGYEVELRGRTELKGKGTEETFWLVGKKGFTKPLPVPPPVGKDG QVGHGLQSVEIAAFQRRKQKSSW |
| External Links | |
| GenBank ID Protein | AAB53864.1 |
| UniProtKB/Swiss-Prot ID | O02740 |
| UniProtKB/Swiss-Prot Entry Name | GUC2F_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | U95958 |
| GeneCard ID | GUCY2F |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |