Identification
BMDB Protein ID BMDBP01111
Secondary Accession Numbers None
Name DNA polymerase epsilon subunit 2
Synonyms Not Available
Gene Name POLE2
Protein Type Enzyme
Biological Properties
General Function Involved in DNA binding
Specific Function Accessory component of the DNA polymerase epsilon complex (By similarity). Participates in DNA repair and in chromosomal DNA replication (By similarity).
Pathways Not Available
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 10
Locus Not Available
SNPs POLE2
Gene Sequence
>1584 bp
ATGGCGCCTGAGCGGTTAAGGAGCCGGGCGCTCTCCGCCTTCAAGCTTCGCGGATTGATG
CTCCGGGGCGAAGCTGTTAAGTACCTCACAGAAGCTCTTCAGTCTATCAATGAAATAGAG
CTTGAAGATGCACTGGAAAAGATCATCGATGCAGTTGAAAAGCAACCCTTGTCATCAAAC
ATGATTGAACGATCAGTAGTGGAAGCAGCAGTCCAGGAATGCAGTCAGTCAGTAGATGAA
ACTATAGATCATATCTTCAATATCATAGGAGCATTTGATATCCCACGCTTTGTGTACAAT
TCAGAAAGAAAAAAATTTCTTCCTTTATTAATGACCAACCACCCTGCACCAAATTTATTT
GGGACAGCAAGAGATAAAGCAGAGCTGTTTCGTGAACGATACACAATTTTGCACCAGAGA
ACCCACAGACATGAATTATTTACTCCTCCAGTGATTGGTTCTCACCCTGATGAAAGTGGA
AGCAAATTCCAGCTTAAGACAATAGAAACCCTATTGGGCAGTACAAGCAAAATTGGAGAT
GTGATTGTTCTTGGGATGATAACCCAGTTAAAAGAGGGAAAATTTTTTCTGGAAGACCCT
ACAGGAACAATACAACTGGATCTTAGTAAAGCTCAGTTTCATAGTGGTTTATACACAGAA
TCATGCTTTGTCTTAGCAGAGGGTTGGTTTGAAGATCAGGTGTTTCATGTCAATGCCTTT
GGATTTCCACCCACTGAACCCTCTAGTACTACTAGGGCATACTATGGAAATACTAATTTT
TTCGGAGGGCCTTCTAATACATCTGTGAAGACTTCTGCAAAACTAAAACAACTAGAGGAT
GAGAATAAAGATGCCATGTTTGTCTTTATATCTGATGTTTGGTTGGACCAAGTAGAAGTA
TTGGAAAAACTTCACATCATGTTTTCTGGTTACTCACCAGCACCTCCAACCTGCTTTATT
CTGTGTGGTAATTTTTCATCTGCACCTTATGGAAAAAATCAAGTTCAAGCTTTGAAAGAT
TCCCTAAAAACTTTGGCAGATATAATATGCGGATACCCAAATATTCATCAAAGTAGTCGT
TTTGTGTTTGTACCTGGCCCAGAGGATCCTGGATTTGGTTCCATCTTACCAAGGCCACCA
TTTGCTGAAAGCATCACTAATGAATTCAGGCAAAGAGTACCATTTTCAGTTTTTACTACT
AATCCTTGCAGAATTCAGTATTGTACACAAGAAATTATTGTCTTTCGTGAAGACTTAGTG
AATAAAATGTGCAGAAACTGTGTCCGTTTTCCCAGTAGCAATTTGGATATTCCTAATCAT
TTTGTAAAGACTGTCTTATCCCAAGGACACCTGACTCCTCTCCCTCTCTATGTCTGCCCA
GTGTATTGGGCGTATGACTATGCTCTGAGAGTGTACCCTGTGCCTGACCTACTTGTCATC
GCAGACAAATATGATCCTTTTACTTTGACCAATACCGAATGCCTCTGCATAAACCCTGGC
TCTTTTCCAAGAAGTGGATTTTCATTCAAAGTTTTTTATCCTTCCAATAAGGTAGTAGAA
GATAGCAAACTTCAAGGGTTTTGA
Protein Properties
Number of Residues 527
Molecular Weight 59496.0
Theoretical pI 6.1
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence
>DNA polymerase epsilon subunit 2
MAPERLRSRALSAFKLRGLMLRGEAVKYLTEALQSINEIELEDALEKIIDAVEKQPLSSN
MIERSVVEAAVQECSQSVDETIDHIFNIIGAFDIPRFVYNSERKKFLPLLMTNHPAPNLF
GTARDKAELFRERYTILHQRTHRHELFTPPVIGSHPDESGSKFQLKTIETLLGSTSKIGD
VIVLGMITQLKEGKFFLEDPTGTIQLDLSKAQFHSGLYTESCFVLAEGWFEDQVFHVNAF
GFPPTEPSSTTRAYYGNTNFFGGPSNTSVKTSAKLKQLEDENKDAMFVFISDVWLDQVEV
LEKLHIMFSGYSPAPPTCFILCGNFSSAPYGKNQVQALKDSLKTLADIICGYPNIHQSSR
FVFVPGPEDPGFGSILPRPPFAESITNEFRQRVPFSVFTTNPCRIQYCTQEIIVFREDLV
NKMCRNCVRFPSSNLDIPNHFVKTVLSQGHLTPLPLYVCPVYWAYDYALRVYPVPDLLVI
ADKYDPFTLTNTECLCINPGSFPRSGFSFKVFYPSNKVVEDSKLQGF
GenBank ID Protein AAI34763.1
UniProtKB/Swiss-Prot ID A7YWS7
UniProtKB/Swiss-Prot Entry Name DPOE2_BOVIN
PDB IDs Not Available
GenBank Gene ID BC134762
GeneCard ID POLE2
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available