Identification
BMDB Protein ID BMDBP01128
Secondary Accession Numbers None
Name Phosphomannomutase 2
Synonyms Not Available
Gene Name PMM2
Protein Type Enzyme
Biological Properties
General Function Involved in phosphomannomutase activity
Specific Function Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.
Pathways
  • Alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2
  • Fructose and Mannose Degradation
  • GDP-alpha-D-mannose biosynthesis
  • Nucleotide-sugar biosynthesis
Reactions
D-Mannose 1-phosphate → Mannose 6-phosphate details
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 25
Locus Not Available
SNPs PMM2
Gene Sequence
>741 bp
ATGGCTGCGCCCGGTCCAGCGCTCTGCCTTTTCGACGTGGACGGGACCCTGACGGCCCCG
CGGCAGAAAATTACCAAAGACATGGATTGCTTTCTGCAAAAACTGAGGCAGAAGATCAAA
ATTGGTGTCGTCGGCGGGTCGGACTTTGAGAAAGTACAGGAGCAGCTGGGAGATGACGTT
ATTAAAAAATATGATTACGTGTTTCCAGAAAATGGCTTGGTAGCATACAGAGATGGGAAA
CTCTTGTGTAAACAGAATATTCAAGGTCACCTGGGTGAAGCCCTAATCCAGGATTTAATC
AACTACTGTCTGAGCTACATCGCGAAAATCAAGCTCCCGAAGAAGAGGGGCACTTTCATA
GAGTTCCGTAACGGGATGCTGAACGTGTCGCCGATCGGAAGAAGCTGCAGCCAGGAAGAA
CGCATTGAGTTCTACGAGCTGGATCAGAAAGAAAACATAAGACAAAAGTTCGTGGAGGAC
CTGCGAAAAGAGTTTGCTGGGAAAGGCCTCACGTTTTCCATAGGAGGCCAGATCAGCTTC
GATGTCTTCCCCGATGGCTGGGACAAGAGGTACTGCCTGGGACACGTGGAGAAGGACGGC
TATAAGACCATCTATTTCTTCGGCGACAAAACCATGCCAGGCGGGAATGACCACGAGATC
TTCACAGACCCCAGGACAGTGGGCTACACAGTGGCGGCGCCGGAGGACACGCGCAGGATC
TGCGAGGAGCTCTTCTGCTGA
Protein Properties
Number of Residues 246
Molecular Weight 27997.0
Theoretical pI 6.29
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence
>Phosphomannomutase 2
MAAPGPALCLFDVDGTLTAPRQKITKDMDCFLQKLRQKIKIGVVGGSDFEKVQEQLGDDV
IKKYDYVFPENGLVAYRDGKLLCKQNIQGHLGEALIQDLINYCLSYIAKIKLPKKRGTFI
EFRNGMLNVSPIGRSCSQEERIEFYELDQKENIRQKFVEDLRKEFAGKGLTFSIGGQISF
DVFPDGWDKRYCLGHVEKDGYKTIYFFGDKTMPGGNDHEIFTDPRTVGYTVAAPEDTRRI
CEELFC
GenBank ID Protein AAI02818.1
UniProtKB/Swiss-Prot ID Q3SZJ9
UniProtKB/Swiss-Prot Entry Name PMM2_BOVIN
PDB IDs Not Available
GenBank Gene ID BC102817
GeneCard ID PMM2
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available