Identification |
BMDB Protein ID
| BMDBP01128 |
Secondary Accession Numbers
| None |
Name
| Phosphomannomutase 2 |
Synonyms
|
Not Available
|
Gene Name
| PMM2 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in phosphomannomutase activity |
Specific Function
| Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. |
Pathways
|
- Alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2
- Fructose and Mannose Degradation
- GDP-alpha-D-mannose biosynthesis
- Nucleotide-sugar biosynthesis
|
Reactions
|
D-Mannose 1-phosphate → Mannose 6-phosphate |
details
|
|
GO Classification
|
Not Available
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| 25 |
Locus
| Not Available |
SNPs
| PMM2 |
Gene Sequence
|
>741 bp
ATGGCTGCGCCCGGTCCAGCGCTCTGCCTTTTCGACGTGGACGGGACCCTGACGGCCCCG
CGGCAGAAAATTACCAAAGACATGGATTGCTTTCTGCAAAAACTGAGGCAGAAGATCAAA
ATTGGTGTCGTCGGCGGGTCGGACTTTGAGAAAGTACAGGAGCAGCTGGGAGATGACGTT
ATTAAAAAATATGATTACGTGTTTCCAGAAAATGGCTTGGTAGCATACAGAGATGGGAAA
CTCTTGTGTAAACAGAATATTCAAGGTCACCTGGGTGAAGCCCTAATCCAGGATTTAATC
AACTACTGTCTGAGCTACATCGCGAAAATCAAGCTCCCGAAGAAGAGGGGCACTTTCATA
GAGTTCCGTAACGGGATGCTGAACGTGTCGCCGATCGGAAGAAGCTGCAGCCAGGAAGAA
CGCATTGAGTTCTACGAGCTGGATCAGAAAGAAAACATAAGACAAAAGTTCGTGGAGGAC
CTGCGAAAAGAGTTTGCTGGGAAAGGCCTCACGTTTTCCATAGGAGGCCAGATCAGCTTC
GATGTCTTCCCCGATGGCTGGGACAAGAGGTACTGCCTGGGACACGTGGAGAAGGACGGC
TATAAGACCATCTATTTCTTCGGCGACAAAACCATGCCAGGCGGGAATGACCACGAGATC
TTCACAGACCCCAGGACAGTGGGCTACACAGTGGCGGCGCCGGAGGACACGCGCAGGATC
TGCGAGGAGCTCTTCTGCTGA
|
Protein Properties |
Number of Residues
| 246 |
Molecular Weight
| 27997.0 |
Theoretical pI
| 6.29 |
Pfam Domain Function
|
Not Available |
Signals
|
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Phosphomannomutase 2
MAAPGPALCLFDVDGTLTAPRQKITKDMDCFLQKLRQKIKIGVVGGSDFEKVQEQLGDDV
IKKYDYVFPENGLVAYRDGKLLCKQNIQGHLGEALIQDLINYCLSYIAKIKLPKKRGTFI
EFRNGMLNVSPIGRSCSQEERIEFYELDQKENIRQKFVEDLRKEFAGKGLTFSIGGQISF
DVFPDGWDKRYCLGHVEKDGYKTIYFFGDKTMPGGNDHEIFTDPRTVGYTVAAPEDTRRI
CEELFC
|
External Links |
GenBank ID Protein
| AAI02818.1 |
UniProtKB/Swiss-Prot ID
| Q3SZJ9 |
UniProtKB/Swiss-Prot Entry Name
| PMM2_BOVIN |
PDB IDs
|
Not Available |
GenBank Gene ID
| BC102817 |
GeneCard ID
| PMM2 |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| Not Available |