| Identification |
|---|
| BMDB Protein ID
| BMDBP01138 |
| Secondary Accession Numbers
| |
| Name
| Palmitoyl-protein thioesterase 1 |
| Synonyms
|
Not Available
|
| Gene Name
| PPT1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in palmitoyl-(protein) hydrolase activity |
| Specific Function
| Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons. |
| Pathways
|
Not Available
|
| Reactions
|
| Palmityl-CoA + Water → Palmitic acid + Coenzyme A |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| Not Available |
| SNPs
| PPT1 |
| Gene Sequence
|
>921 bp
ATGGCGTCGTCCAGCTGCTTGTGGCTCTTGGCTCTCGCTTTCCTGCTGGGTTCCTGCGCT
TCCCTGGCGCTGGGGCATCTCGACCCGCCGGCTCCCCTGCCGCTGGTGATCTGGCATGGG
ATGGGAGACAGCTGTTGTAATCCCTTAAGTATGGGTGCTATTAAAAAAATGGTTGAGAAG
AAAATACCTGGAATTCACGTCTTGTCTTTAGAGATTGGGAAGACTCTCAGAGAGGATGTG
GAGAACAGCTTCTTTTTGAATGTCAACTCCCAAGTAACAACAGTGTGTCAGATTCTTGCT
AAGGATCCTAAATTGCAGCAAGGCTACAATGCTATGGGATTCTCCCAGGGAGGCCAGTTT
CTGCGGGCAGTGGCTCAGAGATGCCCATCACCTCCCATGGTCAACCTCATCTCAGTTGGG
GGACAACATCAAGGTGTTTTTGGACTCCCTCGGTGCCCAGGAGAAAGCTCACACATCTGT
GACTTCATCAGAAAAACACTGAACGCTGGGGCTTACAACAAGGCTATACAGGAACGCCTG
GTGCAAGCAGAATACTGGCACGACCCCATCAGGGAGGACATATACCGCAACCACAGCATC
TTCCTGGCAGATATTAATCAAGAGAGAGGTGTCAATGAGTCCTACAAGAAAAACCTGATG
GCCCTCAAGAAGTTTGTGATGGTGAAATTCCTCAATGATACCATTGTGGACCCTGTGGAT
TCTGAGTGGTTTGGATTTTACAGAAGTGGCCAAGCCAAGGAGACCATTCCCTTACAGGAG
AGCACCCTATACACACAGGACCGCCTGGGGCTAAAGGCAATGGACAAGGCCGGACAGCTG
GTGTTCCTGGCTCTTGAAGGTGACCATCTTCAACTGTCTGAAGAATGGTTTTACGCCCAC
ATCATACCCTTCCTTGAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 306 |
| Molecular Weight
| 34142.0 |
| Theoretical pI
| 6.78 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Palmitoyl-protein thioesterase 1
MASSSCLWLLALAFLLGSCASLALGHLDPPAPLPLVIWHGMGDSCCNPLSMGAIKKMVEK
KIPGIHVLSLEIGKTLREDVENSFFLNVNSQVTTVCQILAKDPKLQQGYNAMGFSQGGQF
LRAVAQRCPSPPMVNLISVGGQHQGVFGLPRCPGESSHICDFIRKTLNAGAYNKAIQERL
VQAEYWHDPIREDIYRNHSIFLADINQERGVNESYKKNLMALKKFVMVKFLNDTIVDPVD
SEWFGFYRSGQAKETIPLQESTLYTQDRLGLKAMDKAGQLVFLALEGDHLQLSEEWFYAH
IIPFLE
|
| External Links |
|---|
| GenBank ID Protein
| AAA59357.1 |
| UniProtKB/Swiss-Prot ID
| P45478 |
| UniProtKB/Swiss-Prot Entry Name
| PPT1_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| L34261 |
| GeneCard ID
| PPT1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
