| Identification |
|---|
| BMDB Protein ID
| BMDBP01164 |
| Secondary Accession Numbers
| |
| Name
| Guanylate kinase |
| Synonyms
|
Not Available
|
| Gene Name
| GUK1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Nucleotide transport and metabolism |
| Specific Function
| Catalyzes the phosphorylation of GMP to GDP. Essential enzyme for recycling GMP and indirectly, cyclic GMP (cGMP) (PubMed:8243671, PubMed:29515371, PubMed:7911663). Involved in the cGMP metabolism in photoreceptors (PubMed:29515371, PubMed:8243671). |
| Pathways
|
Not Available
|
| Reactions
|
| Adenosine triphosphate + Guanosine monophosphate → ADP + Guanosine diphosphate |
details
|
| Adenosine triphosphate + 2'-Deoxyguanosine 5'-monophosphate → ADP + dGDP |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 7 |
| Locus
| Not Available |
| SNPs
| GUK1 |
| Gene Sequence
|
>597 bp
ATGTCAGGACCAAGGCCCGTTGTCCTGAGCGGACCCTCAGGGGCTGGGAAGAGCACCCTA
CTGAAGAAACTCCTGCAGGAACATGGCAGCATCTTTGGCTTCAGCGTGTCCCACACGACA
AGGGACCCGAGGCCAGGAGAGGAGAACGGCAAAGATTACTACTTTGTGACCAGGGAGGTG
ATGCAGCGCGACATTGCTGCTGGAGACTTCATCGAGCACGCTGAGTTCTCAGGGAACTTG
TATGGGACCAGCAAGGCCGCCGTGCGGGCCGTGCAGGCCATGAACCGCATCTGCGTGCTG
GACGTGGACCTGCAGGGCGTGCGCAACATCAAGAAGACCGACCTGCGGCCCATCTACATC
TTCGTGCAGCCGCCCTCACTGGATGTCCTGGAGCAGCGGCTGCGACAGCGGAACACAGAG
ACAGAGGAGAGCCTGGCCAAGCGTCTGGCGGCTGCCCGGGCTGACATGGAGAGCAGCAAG
GAGCCCGGCCTGTTTGACCTGATCATCGTCAACGACAGTCTGGACAAGGCCTACTGGGCC
CTGAAGGAGGCGCTCTCCGAGGAAATAAAGAAGGCCCAAGGCACTGGTCAGTCCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 198 |
| Molecular Weight
| 21910.0 |
| Theoretical pI
| 7.59 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Guanylate kinase
MSGPRPVVLSGPSGAGKSTLLKKLLQEHGSIFGFSVSHTTRDPRPGEENGKDYYFVTREV
MQRDIAAGDFIEHAEFSGNLYGTSKAAVRAVQAMNRICVLDVDLQGVRNIKKTDLRPIYI
FVQPPSLDVLEQRLRQRNTETEESLAKRLAAARADMESSKEPGLFDLIIVNDSLDKAYWA
LKEALSEEIKKAQGTGQS
|
| External Links |
|---|
| GenBank ID Protein
| CAA47423.1 |
| UniProtKB/Swiss-Prot ID
| P46195 |
| UniProtKB/Swiss-Prot Entry Name
| KGUA_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| X67029 |
| GeneCard ID
| GUK1 |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
