Showing Protein Cyclin-dependent kinase 10 (BMDBP01180)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01180 |
| Secondary Accession Numbers | None |
| Name | Cyclin-dependent kinase 10 |
| Synonyms | Not Available |
| Gene Name | CDK10 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in ATP binding |
| Specific Function | Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells). Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators such as PKN2. Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and promotion of RhoA signaling. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 18 |
| Locus | Not Available |
| SNPs | CDK10 |
| Gene Sequence |
>1086 bp ATGGGGGAGCCGGAGCCGGAGCAGATCCGTTTGAAGTGTGTCCGTAAAGAAGGCTTCTTC ACGGTGCCTCCAGAGCACAGGCTGGGACGGTGCCGGAGCGTGAAGGAGTTTGAGAAGCTG AATCGCATTGGGGAAGGCACCTATGGCATCGTATATCGGGCCCGGGATACCCACACAGAT GAGATTGTCGCCCTGAAGAAAGTGCGGATGGACAAGGAGAAGGATGGGGTCCCCATCAGC AGCCTTCGAGAGATCACACTGCTGCTTCGCCTCCGCCATCCCAACATTGTGGAGCTGAAG GAGGTGGTTGTGGGGAACCACCTGGAGAGCATCTTCCTGGTGATGGGCTACTGTGAGCAA GACCTGGCCAGCCTTCTGGAGAACATGCCAACACCCTTCTCTGAGGCCCAGGTCAAGTGC ATCGTGCTGCAGGTGCTCCGGGGCCTCCAGTACCTGCACCGGAATTTCATCATCCACAGG GATCTGAAGGTCTCTAACTTGCTCATGACGGATAAGGGCTGCGTGAAGACAGCGGATTTT GGTCTGGCCCGGGCCTATGGCATCCCAGTGAAGCCAATGACTCCCAAGGTGGTCACACTC TGGTACCGAGCCCCTGAACTGCTGCTGGGAACCACCACGCAGACCACCAGCATCGACATG TGGGCGGTGGGCTGCATCCTGGCTGAGCTGCTGGCCCATAAGCCCCTTCTCCCCGGCACT TCCGAGATCCACCAGGTGGACCTGATCGTGCAGCTGCTGGGGACCCCCAGTGAGAACATC TGGCCGGGCTTCTCTCAGCTGCCGCTGGCCAGCCAGTACAGCCTGCGGAAGCAGCCCTAC AACAACCTGAAGCATAAGTTCCCGTGGCTCTCAGAGGCTGGCCTGCGCCTGATGAACCTC CTCTTCATGTACGACCCTAAGAAAAGGGCGACGGCTGGTGACTGCCTGGAGAGCTCCTAC TTCAAGGAGAAGCCCCTGCCCTGCGAGCCGGAGCTCATGCCCACCTTCCCCCACCATCGT AACAAGCGTGCCACCCCGGCCACATCCTTGGGCACTGAGAGCCAGAGCCGGCGCGGCAGA CCCTGA |
| Protein Properties | |
| Number of Residues | 361 |
| Molecular Weight | 41047.0 |
| Theoretical pI | 9.32 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Cell division protein kinase 10 MGEPEPEQIRLKCVRKEGFFTVPPEHRLGRCRSVKEFEKLNRIGEGTYGIVYRARDTHTD EIVALKKVRMDKEKDGVPISSLREITLLLRLRHPNIVELKEVVVGNHLESIFLVMGYCEQ DLASLLENMPTPFSEAQVKCIVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADF GLARAYGIPVKPMTPKVVTLWYRAPELLLGTTTQTTSIDMWAVGCILAELLAHKPLLPGT SEIHQVDLIVQLLGTPSENIWPGFSQLPLASQYSLRKQPYNNLKHKFPWLSEAGLRLMNL LFMYDPKKRATAGDCLESSYFKEKPLPCEPELMPTFPHHRNKRATPATSLGTESQSRRGR P |
| External Links | |
| GenBank ID Protein | AAI09955.1 |
| UniProtKB/Swiss-Prot ID | Q2TBL8 |
| UniProtKB/Swiss-Prot Entry Name | CDK10_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC109954 |
| GeneCard ID | CDK10 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |