Showing Protein Casein kinase I isoform alpha (BMDBP01216)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01216 |
| Secondary Accession Numbers | None |
| Name | Casein kinase I isoform alpha |
| Synonyms | Not Available |
| Gene Name | CSNK1A1 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in ATP binding |
| Specific Function | Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis. May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration. |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 7 |
| Locus | Not Available |
| SNPs | CSNK1A1 |
| Gene Sequence |
>978 bp ATGGCGAGCAGCAGCGGCTCCAAGGCCGAATTCATTGTCGGAGGGAAATATAAACTGGTA CGGAAGATCGGGTCTGGCTCCTTCGGGGACATTTATTTGGCGATCAACATCACCAACGGC GAGGAGGTGGCAGTGAAGCTAGAATCCCAGAAGGCCAGGCATCCCCAGTTGCTGTACGAG AGCAAACTCTATAAGATTCTTCAAGGTGGGGTTGGCATCCCCCACATACGGTGGTATGGT CAGGAAAAAGACTATAACGTGCTAGTTATGGATCTTCTTGGACCCAGCCTTGAAGACCTC TTCAATTTCTGTTCAAGAAGGTTCACAATGAAAACTGTACTTATGTTAGCTGACCAGATG ATCAGTAGAATCGAATATGTGCATACAAAGAATTTTATACACAGAGACATTAAACCAGAT AACTTCCTAATGGGTATTGGGCGTCACTGTAATAAGTTATTCCTTATTGATTTTGGTTTG GCCAAAAAGTACAGAGACAACAGGACAAGGCAACACATACCATACAGAGAAGATAAAAAT CTCACTGGCACTGCTCGGTATGCTAGCATCAATGCACATCTTGGTATTGAACAAAGTCGC CGAGATGACATGGAATCATTAGGATATGTTTTGATGTATTTTAATAGAACCAGCCTGCCA TGGCAAGGACTAAAGGCTGCAACAAAAAAGCAAAAATATGAAAAAATTAGCGAAAAGAAG ATGTCCACACCCGTTGAAGTTTTATGTAAGGGATTTCCTGCAGAATTTGCCATGTACTTA AACTATTGTCGTGGGCTGCGCTTTGAGGAAGCCCCGGATTACATGTACCTGAGGCAGCTA TTCCGCATTCTTTTCAGGACCCTGAATCACCAATATGACTACACATTTGATTGGACAATG TTAAAGCAGAAAGCAGCACAGCAGGCAGCCTCTTCAAGTGGGCAGGGTCAGCAGGCCCAA ACCCCCACAGGTTTCTAA |
| Protein Properties | |
| Number of Residues | 325 |
| Molecular Weight | 37567.0 |
| Theoretical pI | 9.89 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Casein kinase I isoform alpha MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM LKQKAAQQAASSSGQGQQAQTPTGF |
| External Links | |
| GenBank ID Protein | AAA30451.1 |
| UniProtKB/Swiss-Prot ID | P67827 |
| UniProtKB/Swiss-Prot Entry Name | KC1A_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | M76543 |
| GeneCard ID | CSNK1A1 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |