| Identification |
|---|
| BMDB Protein ID
| BMDBP01229 |
| Secondary Accession Numbers
| None |
| Name
| 6-phosphogluconolactonase |
| Synonyms
|
Not Available
|
| Gene Name
| PGLS |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Carbohydrate transport and metabolism |
| Specific Function
| Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. |
| Pathways
|
- Carbohydrate degradation
- D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3
- Pentose Phosphate Pathway
- Warburg Effect
|
| Reactions
|
| Gluconolactone + Water → 6-Phosphogluconic acid |
details
|
| 6-Phosphonoglucono-D-lactone + Water → 6-Phosphogluconic acid + Hydrogen |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 7 |
| Locus
| Not Available |
| SNPs
| PGLS |
| Gene Sequence
|
>777 bp
ATGGCCGCGCCGGCCCCCCGCCTCATCTCTGTCTTCTCGAGCCCGCAGGAGCTGGGTGCG
TCTTTGGCGCAACTGGTAGTACAGCAGGCAGCATGCTGCCTGGCGGATGCCGGCGCCCGC
TTCACGCTCGGCTTGTCCGGCGGCAGCCTTGTCTCCATGCTAGCCCGCGAGCTGCCCGCT
GCCGCCGCCCCCGCTGGACCCGCTAGCCTCGCGCGCTGGACGCTGGGCTTCTGCGACGAG
CGCCTTGTGCCCTTCGAGCACGCCGAGAGCACGTACGGCCTGTACCGGACCCACCTGCTC
TCCAAGCTCCCTATCTTCGACAGCCAGGTGATCACCATCAACCCTGCATTGCCTGTGGAG
GAGGCGGCTGAGGACTACGCCAAGAAGCTGAGACAGGCCTTCCAAGGGGACTCCATCCCG
GTTTTTGACCTGCTGATTCTGGGTGTGGGTCCTGATGGCCACACCTGCTCACTCTTCCCA
GACCACCCCCTCCTGCAGGAGCGGGAGAAAATTGTGGCCCCCATCAGTGACTCTCCGAAA
CCACCTCCGCAGCGCGTGACCCTCACTCTTCCCGTGCTGAACGCAGCTCGAACGGTCATC
TATGTGGCGACAGGAGAAGGCAAGGCAGCTATTCTGAAGCGCATTTTGGAGGACAAGGAG
GAGAACCCACTCCCCGCCGCACTGGTTCAGCCCAGCGCTGGGAAACTTTGCTGGTTTCTG
GACGAGGCAGCAGCCCGACTCCTGACCGTGCCCTTCGAGAAGCATTCCACTTTGTAA
|
| Protein Properties |
|---|
| Number of Residues
| 258 |
| Molecular Weight
| 27547.0 |
| Theoretical pI
| 5.65 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>6-phosphogluconolactonase
MAAPAPRLISVFSSPQELGASLAQLVVQQAACCLADAGARFTLGLSGGSLVSMLARELPA
AAAPAGPASLARWTLGFCDERLVPFEHAESTYGLYRTHLLSKLPIFDSQVITINPALPVE
EAAEDYAKKLRQAFQGDSIPVFDLLILGVGPDGHTCSLFPDHPLLQEREKIVAPISDSPK
PPPQRVTLTLPVLNAARTVIYVATGEGKAAILKRILEDKEENPLPAALVQPSAGKLCWFL
DEAAARLLTVPFEKHSTL
|
| External Links |
|---|
| GenBank ID Protein
| AAI09790.1 |
| UniProtKB/Swiss-Prot ID
| Q2TBQ8 |
| UniProtKB/Swiss-Prot Entry Name
| 6PGL_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC109789 |
| GeneCard ID
| PGLS |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
