Showing Protein M-phase inducer phosphatase 1 (BMDBP01233)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01233 |
| Secondary Accession Numbers | None |
| Name | M-phase inducer phosphatase 1 |
| Synonyms | Not Available |
| Gene Name | CDC25A |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in protein tyrosine phosphatase activity |
| Specific Function | Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro (By similarity). |
| Pathways | Not Available |
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 22 |
| Locus | Not Available |
| SNPs | CDC25A |
| Gene Sequence |
>1578 bp ATGGAACTGGGCCCGGAGCCCCCGCACCGCCGCCGCCTGCTCTTCGCCTGCAGCCCCCCG CCCGCACCGCAGCCCGTCGTGAAGGCGCTGTTTGGCACGCCAGCCGCCGGGGGCCTGTCG CCTGTCACCAACCTGACGGTCACCATGGACCAGCTGCAGGGACTGGGCAGTGAGTATGAA CAACCCATAGAGGTGAAAAACAGCAGTCTGCAGAGAATGGGCTCCTCCGAATCAACTGAT TCAGGCTTCTGTCTGGATTCTCCTGGGCCCTTGGATAGTAAAGAAAACCTTGAAAATCCC ATGAGGAGAATAAATTCCCTACCTCAGAAGCTCTTGGGGTGTAGCCCAGCTCTGAAGAGG AGCCATTCTGATTCTCTTGACCATGATGTCTTTCAGCTGATTGACCAGGATGAGAACAAG GAAAATCAAGTCTTTGAGTTTAAGAAGCCAATAAGACCTGCATCTCGAGGCTGCCTACAT GTTCACGGACTGGAGGAGGGTAAAGATGTCTTCACACAGAGGCAGAACTCCGCCCCAGCT CGGATGCTTTCCTCAAATGAAAGAGATGGCAATGAACCAGGGAATTCCATTCCTTTTATG CCCCAGTCACCTGTGACTCCCACTTTGTCTGATGAGGATGATGGCTTCATGGATCTTCTT GATGGAGAGAATTTGAAGAATGATGAAGAGACCCCATCCTGCATGGCCAGCCTCTGGACA GCTCCCCTTGTCATGAGAAGAACTAATAACCTAGGCAATCGCTGCAAGCTGTTTGACTCC CCTTCAGCGTCGTGTAGCTCTACCATCCGGTCAATGTTGAAAAGACCAGACCGATCACTA GAGGAGTCCCCAGGTGGAAGCAGGAAGCGGAGGAAAAGCGTGGCTGGGGCCAGTCCGGAA GAGGCAGCTAGTCCAGAGAAGCCCCAGGAGATTCTACATCATCAGTCTTTATCCCTAGCA TCTTCCCCAAAAGGGACCATTGAGAACATTTTGGATAATGACCCAAGGGACCTTATAGGA GACTTCTCCAAGGGTTACCTCTTTCATACCGTTGCTGGAAAGCATCAGGATTTAAAATAC ATCTCTCCAGAAATTATTACATCTGTTTTGAATGGCAAGTTTGCCAACCTCATTAAAGAG TTTGTCATCATCGACTGCCGATACCCATATGAATATGAGGGAGGCCACATCAAGGGTGCA GTGAACTTGCACATGGAAGAGGAGGTTGAAGAGTTCTTACTCAAGAAGCCTATCGTACCT ACGGATGGCAAGCGTGTTATCGTGGTGTTCCACTGCGAGTTCTCTTCTGAGCGCGGCCCT CGCATGTGCCGATACGTGAGAGAGAGGGATCGGCTCGGTAACGAGTACCCCAAACTCCAC TACCCAGAGCTGTATGTCCTGAAGGGCGGATACAAGGAGTTCTTCCTGAAATGCCAGTCT CACTGCGAGCCCCCCAGCTACCGGCCCATGCACCACGAGGACTTTAAAGAAGACCTGAAG AAATTCCGCACCAAGAGCCGGACCTGGGCCGGGGAGAAGAGCAAGAGGGAGATGTACAGC CGCCTGAAGAAGCTCTGA |
| Protein Properties | |
| Number of Residues | 525 |
| Molecular Weight | 59142.0 |
| Theoretical pI | 7.07 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>M-phase inducer phosphatase 1 MELGPEPPHRRRLLFACSPPPAPQPVVKALFGTPAAGGLSPVTNLTVTMDQLQGLGSEYE QPIEVKNSSLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRINSLPQKLLGCSPALKR SHSDSLDHDVFQLIDQDENKENQVFEFKKPIRPASRGCLHVHGLEEGKDVFTQRQNSAPA RMLSSNERDGNEPGNSIPFMPQSPVTPTLSDEDDGFMDLLDGENLKNDEETPSCMASLWT APLVMRRTNNLGNRCKLFDSPSASCSSTIRSMLKRPDRSLEESPGGSRKRRKSVAGASPE EAASPEKPQEILHHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKY ISPEIITSVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEEFLLKKPIVP TDGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFLKCQS HCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL |
| External Links | |
| GenBank ID Protein | AAI51494.1 |
| UniProtKB/Swiss-Prot ID | A7MBD1 |
| UniProtKB/Swiss-Prot Entry Name | MPIP1_BOVIN |
| PDB IDs | |
| GenBank Gene ID | BC151493 |
| GeneCard ID | CDC25A |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |