Showing Protein Receptor-type tyrosine-protein phosphatase F (BMDBP01235)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01235 |
| Secondary Accession Numbers | None |
| Name | Receptor-type tyrosine-protein phosphatase F |
| Synonyms | Not Available |
| Gene Name | PTPRF |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in protein binding |
| Specific Function | Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity (By similarity). |
| Pathways |
|
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 3 |
| Locus | Not Available |
| SNPs | PTPRF |
| Gene Sequence |
>5697 bp ATGACCCCTGAGCCAGCCCCAGGGAGGACGATGGTGCCCCTTGTCCCTGCACTTGTGATG CTTGGTTTGGTGGCAGGTGCCCATGGCGACAGCAAACCTGTCTTTGTCAAGGTCCCCGAG GACCAGACTGGATTGTCAGGAGGGGTGGCCTCCTTCGTGTGCCAAGCCACGGGGGAACCC AAGCCGCGCATCACATGGATGAAGAAGGGGAAGAAAGTCAGCTCCCAGCGCTTCGAGGTC ATCGAGTTTGATGACGGGGCAGGGTCTGTGCTGCGGATCCAGCCACTGCGGGTGCAGCGA GACGAAGCCATCTATGAGTGCACGGCCACCAACAGTCTGGGGGAGATCAACACCAGTGCC AAGCTCTCAGTGCTCGAAGAGGAACAGCTGCCCCTTGGGTTCCCCTCCATCGACATGGGG CCTCAGCTGAAGGTGGTGGAGAAGGCCCGCACGGCCACTATGCTGTGTGCAGCAGGCGGG AATCCAGACCCTGAGATCTCTTGGTTCAAGGACTTCCTCCCTGTGGACCCCGCCGCGAGC AACGGCCGCATCAAGCAACTGCGTTCAGGTGCCTTGCAGATTGAGAGCAGCGAGGAGTCG GACCAAGGCAAGTACGAGTGTGTGGCGACCAACTCTGCAGGCACTCGTTACTCGGCCCCT GCCAACCTATATGTGCGAGTGCGCCGCGTGGCTCCGCGTTTCTCCATCCCTCCCAGCAGC CAGGAGGTGATGCCGGGCGGCAGCGTGAACCTGACGTGCGTCGCCGTTGGCGCACCCATG CCCTACGTGAAGTGGATGATGGGGGCCGAAGAGCTCACCAAGGAGGACGAGATGCCGGTC GGCCGCAATGTGCTGGAGCTCAGCAACGTGGTGCGCTCCGCCAACTACACTTGCGTGGCC ATCTCCTCCCTGGGCATGATCGAGGCCACGGCCCAGGTCACCGTGAAAGCCCTGCCGAAG CCTCCAATTGACCTTGTGGTGACAGAGACAACTGCCACCAGCGTCACTCTGACCTGGGAC TCTGGGAACTCAGAGCCTGTATCCTACTATGGCATCCAGTACCGCCCAGCGGGCGCGGAG GGCCCCTTCCAGGAGGTGGACGGCGTGGCCACCACCCGCTACAGCATCGGCGGCCTGAGC CCTTTCTCAGAGTACGCCTTCCGCGTGCTGGCGGTGAACAGCATCGGGCGCGGGCCGCCC AGCGAGGCGGTGCGGGCGCGCACGGGGGAGCAGGCGCCCTCCAGCCCCCCGCGCCGCGTG CAGGCACGCATGCTAAGCGCCAGCACCATGCTGGTGCAGTGGGAGCCGCCCGAGGAGCCT AACGGCCTGGTGCGGGGCTACCGCGTCTACTACACCCCCGACTCCCGCCGCCCTCTGAGC GCCTGGCACAAGCACAACACAGACGCCGGGCTCCTCACCACTGTGGGCAGCCTGCTGCCT GGCATCACCTACAGCCTGCGTGTGCTGGCCTTCACCGCCGTGGGCGACGGCCCCCCCAGC CCCACCATCCAGGTCAAGACGCAGCAGGGAGTGCCTGCCCAGCCCGCGGACTTCCAGGCC GAGGTGGACTCAGACACCAGGATCCAGCTCTCGTGGCTGCTGCCCCCGCAGGAGCGGATC GTCAAGTATGAGCTGGTGTACTGGGCGGCAGAGGACGAGGGCCAGCAGCACAAGGTGACC TTCGACCCCACGTCCTCCTATACCGTAGAGGACCTGAAGCCCGACACACTGTACCGCTTC CAGCTGGCCGCCCGCTCTGAGCTGGGGGTGGGAGTCTTCACCCCCACCATTGAGGCTCGC ACAGCACAGTCCACCCCCTCCGCACCCCCCCAGAAGGTGACGTGTGTGAGCGTGGGCTCC ACCACCGTCCGGGTAAGTTGGGTCCCGCCGCCGGCCGACAGCCGCAACGGCGTCATCACC CAGTACTCGGTGGCCTACGAGGCGGTGGACGGCGAGGACCGTGGGCGGCACGTGGTGGAC GGCATCGGCCGCGAGCACTCCAGCTGGGACCTGGTGGGCCTGGAGAAGTGGACGGAGTAC CGGGTGTGGGTGCGGGCGCACACGGACGTGGGCCCCGGCCCCGAGAGCAGCCCGGTGCTG GTCCGCACCGACGAGGACGTGCCCAGTGGGCCACCGCGGAAGGTGGAGGTGGAGCCGCTC AACTCCACTGCCGTGCGCGTCTCCTGGAAGCTGCCCGTCCCCAGCAAGCAGCATGGCCAG ATCCGCGGCTACCAGGTCACCTACGTGCGGCTGGAGAATGGCGAGCCCCGCGGCGCCCCC ATCATCCAGGACGTCATGCTGGCCGAGGCCCAGGAAACCACCATCAGCGGCCTGACCCCG GAGACCACCTACTCCATCACCGTGGCTGCCTACACCACCAAGGGGGACGGTGCCCGCAGC AAGCCCAAAATTGTCACGACCACAGGGGCAGTCCCAGGACGGCCCACCATGATGGTCAGC ACCACGGCCATGAACACGGCGCTGCTCCAGTGGCACCCGCCCAAGGAGCTGCCCGGGGAG CTCCTGGGCTACCGGCTGCAGTACCGCCGAGCCGACGAGGCGCGGCCCAGCACCATCGAT TTTGGCAAGGACGACCAGCACTTTACGGTCACTGGCCTGCACAAAGGGGCCACCTACATC TTCCGGCTCACTGCCAAGAACCGGGCCGGCCTGGGCGAGGAGTTCGAGAAGGAAATCACG ACCCCCGAGGACGTGCCCAGCGGTTTCCCCCAAAACCTGCGCGTGATAGGGCTGACCACA TCTACCACGGAACTGATCTGGGACCCCCCAGTGCTGGCGGAGAGGAACGGGCGCATCACC AACTACACCGTGGTGTACCGTGACATCAACAGCCAGCAGGAGCTTCAGAACGTCACTGCC GACACCCACCTGACGCTCTCCGGCCTCAAGCCAGACACCACTTACGACATCAAGGTCCGC GCACGCACCAGCAAGGGCGCCGGCCCGCTCAGCCCCAGCATCCAGTCCCGGACCATGCCC GTGGAGCAAGTGTTTGCCAAGAACTTCCGTGTGGAGGCTGCAATGAAGACATCTGTGCTG CTCAGCTGGGAGGTGCCCGACTCCTACAAGTCAGCAGTGCCCTTCAGGATCCTGTACAAT GGGCAGAGCGTGGAGGTGGACGGGCACTCCATGCGGAAGCTGATTGCAGACCTGCAGCCC AACACTGAATACTCATTTGTGCTGATGAACCGCGGCAGCAGCGCGGGGGGCCTGCAACAC CTCGTGTCCATCCGCACGGCCCCCGACCTCCTGCCGCACAAGCCACTGCCAGCCTCGGCC TACATCGAGGACGGCCGCTTCACCCTCACCATGCCCCGCGTGCAGGAACCCGCACTGGTC AGGTGGTTCTACATCATGGTGGTGCCCATTGACCGCATGGGAGGGAGCATGCTGGCGCCA CAGTGGAGCACGCCCGAGGAGCTGGAGCTGGACGAGCTGCTGGAGGCCATCGAGCAGGGC GGCGGGGAGCGGCTGCGGCGCCGGCGGCAGACGGAGCGGCTGAAGCCATACGTGGCCGCT CAGGTGGACGTTCTCCCGGAGACCTTCACCTTGGGGGACAAGAAGAACTATCAAGGCTTC TACAACCGGCCGCTGTCTCCAGACCTGAGCTACCAGTGCTTTGTGCTCGCCTCCCTGAAG GAACCCGTGGACCAGAAGCGCTATGCCTGCAGCCCCTACTCCGATGAGATCGTGGTCCAG GTGACACCAGCCCAGCAGCAGGAGGAACCCGAGCTGCTGTGGGTGACGGGCCCCGTCCTG GCAGTCATTCTCATCGTCCTCATTGTCATCGCCATTCTCCTGTTCAAGAGGAAAAGGACC CACTCCCCATCGTCCAAGGATGAGCAGTCAATTGGGCTGAAGGACTCCTTGCTGGCCCAC TCCTCCGACCCTGTGGAGATGCGGCGGCTCAACTACCAGACCCCAGGTATGCGAGACCAC CCGCCCATCCCCATCACCGACCTAGCTGACAACATCGAGCGCCTCAAAGCCAATGACGGC CTCAAGTTCTCCCAGGAGTACGAGTCAATTGACCCAGGACAGCAGTTCACGTGGGAGAAT TCAAACCTGGAGGTGAACAAGCCGAAGAACCGCTATGCCAACGTCATTGCTTACGACCAC TCTCGAGTCATCCTTACCTCCATCGATGGTGTCCCCGGGAGCGACTACATCAATGCCAAT TACATCGACGGCTACCGCAAGCAGAACGCCTACATTGCCACGCAGGGCCCGCTGCCTGAG ACCATGGGCGATTTCTGGCGGATGGTGTGGGAACAGCGCACAGCCACTGTGGTCATGATG ACGCGGCTGGAGGAGAAGTCCCGGGTGAAATGTGACCAGTACTGGCCAGCTCGTGGCACC GAGACCTATGGCCTCATCCAGGTGACCCTGCTGGACACGGTGGAGCTGGCCACCTACACT GTGCGCACCTTCGCGCTCTACAAGAGTGGCTCCAGTGAGAAGCGGGAGCTGCGTCAGTTC CAGTTCATGGCCTGGCCAGACCACGGAGTCCCCGAGTACCCGACCCCTATCCTGGCCTTC CTGCGGCGGGTCAAGGCTTGCAACCCCCTGGACGCGGGGCCCATGGTGGTGCACTGCAGC GCGGGCGTGGGCCGCACGGGCTGCTTCATCGTCATCGACGCCATGCTGGAGCGGATGAAG CACGAGAAGACAGTGGACATCTACGGCCACGTGACGTGCATGCGGGCGCAGCGCAACTAC ATGGTGCAGACTGAGGACCAGTACGTGTTCATCCACGAGGCGCTGCTGGAGGCCGCCATG TGTGGACACACGGAGGTGCCCGCCCGCAACCTCTACGCCCACATCCAGAAGCTGGGCCAA GTGCCTCCCGGGGAGAGTGTGACTGCCATGGAGCTGGAGTTCAAGTTGCTGGCCAACTCC AAGGCCCACACATCCCGCTTCATCAGCGCCAACCTGCCCTGCAACAAGTTCAAGAACCGC CTGGTGAACATCATGCCCTACGAACTGACCCGTGTGTGTCTGCAGCCCATCCGCGGCGTG GAGGGCTCCGACTACATCAATGCCAGCTTCCTGGATGGCTATCGACAGCAGAAGGCCTAC ATAGCCACACAGGGGCCTCTGGCGGAGAGCACCGAGGATTTCTGGCGCATGTTATGGGAG CACAACTCCACCATCATCGTCATGCTGACCAGGCTTCGGGAGATGGGCCGGGAGAAATGC CACCAGTACTGGCCTGCAGAGCGCTCTGCTCGCTACCAGTACTTTGTCGTCGACCCGATG GCTGAGTACAACATGCCCCAGTATATTCTCCGTGAGTTCAAGGTCACGGATGCCCGGGAT GGGCAGTCGAGGACAATCCGGCAGTTCCAGTTCACAGACTGGCCGGAGCAGGGCGTGCCT AAAACGGGCGAGGGCTTCATCGACTTCATCGGGCAGGTGCACAAGACCAAGGAGCAGTTC GGGCAGGACGGGCCCATCACGGTGCACTGCAGTGCTGGTGTGGGCCGCACTGGGGTGTTC ATCACGCTGAGCATTGTCCTGGAGCGGATGCGCTACGAAGGCGTGGTTGACATGTTCCAG ACCGTGAAGACCCTGCGCACACAGCGCCCAGCCATGGTGCAGACGGAGGACCAGTATCAG CTGTGCTACCGCGCGGCCCTGGAGTACCTCGGAAGCTTTGACCACTATGCAACGTAA |
| Protein Properties | |
| Number of Residues | 1898 |
| Molecular Weight | 211382.0 |
| Theoretical pI | 6.48 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions |
|
| Protein Sequence |
>Receptor-type tyrosine-protein phosphatase F MTPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFVKVPEDQTGLSGGVASFVCQATGEP KPRITWMKKGKKVSSQRFEVIEFDDGAGSVLRIQPLRVQRDEAIYECTATNSLGEINTSA KLSVLEEEQLPLGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPAAS NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSS QEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKEDEMPVGRNVLELSNVVRSANYTCVA ISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVSYYGIQYRPAGAE GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRV QARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPLSAWHKHNTDAGLLTTVGSLLP GITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVDSDTRIQLSWLLPPQERI VKYELVYWAAEDEGQQHKVTFDPTSSYTVEDLKPDTLYRFQLAARSELGVGVFTPTIEAR TAQSTPSAPPQKVTCVSVGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVD GIGREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPL NSTAVRVSWKLPVPSKQHGQIRGYQVTYVRLENGEPRGAPIIQDVMLAEAQETTISGLTP ETTYSITVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMVSTTAMNTALLQWHPPKELPGE LLGYRLQYRRADEARPSTIDFGKDDQHFTVTGLHKGATYIFRLTAKNRAGLGEEFEKEIT TPEDVPSGFPQNLRVIGLTTSTTELIWDPPVLAERNGRITNYTVVYRDINSQQELQNVTA DTHLTLSGLKPDTTYDIKVRARTSKGAGPLSPSIQSRTMPVEQVFAKNFRVEAAMKTSVL LSWEVPDSYKSAVPFRILYNGQSVEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQH LVSIRTAPDLLPHKPLPASAYIEDGRFTLTMPRVQEPALVRWFYIMVVPIDRMGGSMLAP QWSTPEELELDELLEAIEQGGGERLRRRRQTERLKPYVAAQVDVLPETFTLGDKKNYQGF YNRPLSPDLSYQCFVLASLKEPVDQKRYACSPYSDEIVVQVTPAQQQEEPELLWVTGPVL AVILIVLIVIAILLFKRKRTHSPSSKDEQSIGLKDSLLAHSSDPVEMRRLNYQTPGMRDH PPIPITDLADNIERLKANDGLKFSQEYESIDPGQQFTWENSNLEVNKPKNRYANVIAYDH SRVILTSIDGVPGSDYINANYIDGYRKQNAYIATQGPLPETMGDFWRMVWEQRTATVVMM TRLEEKSRVKCDQYWPARGTETYGLIQVTLLDTVELATYTVRTFALYKSGSSEKRELRQF QFMAWPDHGVPEYPTPILAFLRRVKACNPLDAGPMVVHCSAGVGRTGCFIVIDAMLERMK HEKTVDIYGHVTCMRAQRNYMVQTEDQYVFIHEALLEAAMCGHTEVPARNLYAHIQKLGQ VPPGESVTAMELEFKLLANSKAHTSRFISANLPCNKFKNRLVNIMPYELTRVCLQPIRGV EGSDYINASFLDGYRQQKAYIATQGPLAESTEDFWRMLWEHNSTIIVMLTRLREMGREKC HQYWPAERSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTIRQFQFTDWPEQGVP KTGEGFIDFIGQVHKTKEQFGQDGPITVHCSAGVGRTGVFITLSIVLERMRYEGVVDMFQ TVKTLRTQRPAMVQTEDQYQLCYRAALEYLGSFDHYAT |
| External Links | |
| GenBank ID Protein | AAI51593.1 |
| UniProtKB/Swiss-Prot ID | A7MBJ4 |
| UniProtKB/Swiss-Prot Entry Name | PTPRF_BOVIN |
| PDB IDs | |
| GenBank Gene ID | BC151592 |
| GeneCard ID | PTPRF |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |