| Identification |
|---|
| BMDB Protein ID
| BMDBP01239 |
| Secondary Accession Numbers
| None |
| Name
| M-phase inducer phosphatase 3 |
| Synonyms
|
Not Available
|
| Gene Name
| CDC25C |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein tyrosine phosphatase activity |
| Specific Function
| Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activate its kinase activity (By similarity). |
| Pathways
|
Not Available
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 7 |
| Locus
| Not Available |
| SNPs
| CDC25C |
| Gene Sequence
|
>1434 bp
ATGTCTGCAGAATTCTTCTCATCCAAAAGAGAGGAGGGAAGCCTTGCCTCAGGACCTAGT
TTTAGGTCCAATCAGAGGAAGATATTAAACCTGCTCCTTGAGAGAGATGCTTCCTTTTCC
ATCAGTTCAGATCTCCCTACAACTCCAGTGGAGAAGAAACTTTTTGGTGACTCTGCAAAC
CTAAGCATTTTGTCTGGAGGAACCCCAAAACGTTGCCTTGATCTTTCGAATCTTAGCAGC
GGGGAGATGTCTGCCACTCAGCTTACTGCTTCTGCAGACCTTGATGAAACTGGTCATTTG
GAGTCTACAGGACCTGAGCAAGTACGGTTAGCTGGAATGAATTACCGCCAACATCTTATA
AAATGTAGCCCAGCACAGCTGTTTTGTAGCACTCCGAATGCCTTGGAGCATGGCCGCAGG
AAGAAAGATGCAATATGTGGCTCATCTGCAAATAAGGAAAATGACAATGGAAACTTGGTG
GAAAATGAAATGAAACATCTGGGCAGTCCCATTACTACAGTTTCAAAATTACATAAAAAT
CCAGAGCTAGCAGAAGATCAGGCAGAAGAGATATCAGATGAATTGATGGAGTTTTCACTG
GAAGATCAAGAAAAGGCCAAGCCACCTCTGAACTGGAGCTCCCTGTATCGCTCCTCATCA
TTGCCAGACAGCTTAAACAGTCCAAGTTTGAAGCAGGTGGTAAAATTCAAGGACAGCACA
ATACCAGATAAACTAAAAAAGAAGTATTGTTCAAACCAAAAAGAGCTCGGAAAGGGCTTA
GGTCTAAAGAAAATGGTCTCCCTCTGTGACATCAATATGACTCAGATGCTGGAGGAAGAT
TCAAACCAGGGGCCTCTGATTGGTGATTTCTCCAAGGTATGTGCACTGCCAACCGTGTCA
GGGAAACACCAAGATCTGAAGTACGTCAACCCAGAAACAGTGGCTGCCTTACTATCAGGG
GAGTTCCAGGGTCTGATTGAGAAGTTTTATATCATCGATTGCCGCTATCCATATGAGTAC
CTGGGAGGACACATTCAGGGAGCATTAAACTTGCACAGTCAAGAAGAACTATATAACTTC
TTTCTGAAGAAACCCATTGTCCCTTGGGATAACCAGAAAAGAATAGTCATCGTGTTCCAT
TGTGAATTCTCCTCTGAGAGGGGTCCCCGAATGTGCCGTTCTCTGAGAGAAGAGGACAGG
ACTCTGAACCAGTATCCTGCCCTGTACTACCCAGAGCTATACATCCTCAAAGGGGGCTAC
AGAGACTTCTTTCCAGAATATATGGAGCTGTGTGAACCACAGAGCTACTGCCCGATGCAT
CACCAGGACCATAAGGCTGAGCTGCTGAGGTGTCGAAACCAGAGCAAAGCATGGGAAGGA
GAGCGGCAGCTGCAGGAACAGATTGCCTTACTGGTGAAGGATGTGAGCCCATGA
|
| Protein Properties |
|---|
| Number of Residues
| 477 |
| Molecular Weight
| 53794.0 |
| Theoretical pI
| 6.11 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>M-phase inducer phosphatase 3
MSAEFFSSKREEGSLASGPSFRSNQRKILNLLLERDASFSISSDLPTTPVEKKLFGDSAN
LSILSGGTPKRCLDLSNLSSGEMSATQLTASADLDETGHLESTGPEQVRLAGMNYRQHLI
KCSPAQLFCSTPNALEHGRRKKDAICGSSANKENDNGNLVENEMKHLGSPITTVSKLHKN
PELAEDQAEEISDELMEFSLEDQEKAKPPLNWSSLYRSSSLPDSLNSPSLKQVVKFKDST
IPDKLKKKYCSNQKELGKGLGLKKMVSLCDINMTQMLEEDSNQGPLIGDFSKVCALPTVS
GKHQDLKYVNPETVAALLSGEFQGLIEKFYIIDCRYPYEYLGGHIQGALNLHSQEELYNF
FLKKPIVPWDNQKRIVIVFHCEFSSERGPRMCRSLREEDRTLNQYPALYYPELYILKGGY
RDFFPEYMELCEPQSYCPMHHQDHKAELLRCRNQSKAWEGERQLQEQIALLVKDVSP
|
| External Links |
|---|
| GenBank ID Protein
| AAI40631.1 |
| UniProtKB/Swiss-Prot ID
| A5D7P0 |
| UniProtKB/Swiss-Prot Entry Name
| MPIP3_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC140630 |
| GeneCard ID
| CDC25C |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
