Showing Protein Methionine--tRNA ligase, cytoplasmic (BMDBP01251)
| Identification | |||||
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| BMDB Protein ID | BMDBP01251 | ||||
| Secondary Accession Numbers | None | ||||
| Name | Methionine--tRNA ligase, cytoplasmic | ||||
| Synonyms | Not Available | ||||
| Gene Name | MARS1 | ||||
| Protein Type | Enzyme | ||||
| Biological Properties | |||||
| General Function | Translation, ribosomal structure and biogenesis | ||||
| Specific Function | Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Plays a role in the synthesis of ribosomal RNA in the nucleolus. | ||||
| Pathways |
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| Reactions |
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| GO Classification | Not Available | ||||
| Cellular Location | Not Available | ||||
| Gene Properties | |||||
| Chromosome Location | 5 | ||||
| Locus | Not Available | ||||
| SNPs | MARS1 | ||||
| Gene Sequence |
>2697 bp ATGAGGTTGTTCGTGAGTGAGGGCGCTCCGGGGAGTCTGCCTGTGCTGGCCGCGGCCGGG AGGGCCCAGGGCAGAGCGGAGCTGCTCATCAGCACTGTAGGCCCAGAAGAGTGTGTGGTC CCATTCCTGACCCGGCCTAAGGTCCCTGTCTTGCAGCTGGATAGTGGCAACTACCTCTTC TCCACCAGTGCAATCTGTCGATACTTCTTTCTGTTATCTGGCTGGGAGCAAGATGACCTC ACCAACCAGTGGCTGGAATGGGAAGCAACCGAGCTGCAGCCAGCTTTGTCCGCTGCCCTG TACTATTTAGTGGTCCAAGGGAAGAAGGGAGAAGATGTTCTTGGCCCAGTTCGGAGAGCC CTGACGCATATTGACCACAGCTTGAGTCGTCGGAGCTGTCCGTTCCTGGCTGGGGAGACA GAATCTCTAGCTGATATTGTTTTGTGGGGAGCGCTCTACCCGTTACTCCAAGACCCATCC TATCTCCCTGAGGAGCTGGGTGCCCTGCACAGCTGGTTCCAGACACTGAGTTCTCAGGAG CCATGTCAGCGAGCTGCAGAGACTGTGCTGAAGCAGCAGGGTGTCCTGGCCCTCCGGCCC TACCTCCAGAAGCAGCCCCAGCCCAGCTCCCTTGAGGGCAGGCTTGTCAGCAATGAGCCT GAGGAGGAGGAACTGGCTACTCTGTCTGAGGAGGAGATTGCCGTGGCTGTAGCTGCTTGG GAGAAGGGCCTGGAAAGCTTGCCCCCTCTTCGGCCGCAGCAGAATCCAGTGTTGCCCGTG GCTGGGGAGAGAAATGTGCTCATCACCAGCGCCCTCCCTTACGTCAACAACGTCCCCCAC CTTGGAAACATCATCGGCTGTGTGCTCAGTGCCGACGTCTTTGCAAGGTACTCCCGGCTC CGTCAGTGGAACACCCTCTACCTGTGTGGGACAGATGAGTATGGTACAGCGACAGAGACC AAGGCTATGGAGGAGGGACTAACCCCACAGGAAATCTGTGACAAGTACCACGTAATCCAC GCTGACATCTACCGCTGGTTTAATATTTCGTTTGACTTTTTTGGTCGGACTACCACTCCA CAGCAGACCAAAATTACCCAGGACATCTTCCAGCGGCTGTTGGCCCGAGGTTTTGTGCTG CAAGATACTGTGGAGCAACTTCGGTGTGAGCACTGTGCCCGCTTCCTGGCTGACCGCTTT GTGGAGGGTGTGTGTCCCTTCTGTGGATACGAGGAAGCCCGGGGTGACCAGTGTGACAAG TGTGGCAAGCTCATTAATGCCATTGAGCTCAAGAAGCCTCAGTGTAAAGTCTGCCGGTCG TGCCCTGTGGTGAAATCCTCTCAGCACCTGTTTCTGGACCTGCCTAAGCTGGCAGCGCGG GTGGAGGAGTGGTTGGAGAAGACATTGCCTGGCAGTGACTGGACTGCCAACGCCCGGTTC ATCATTCGTTCTTGGCTTCGAGATGGCCTCAAGCCCCGCTGTATAACCCGAGACCTCAAG TGGGGAACCCCTGTGCCCTTAGAAGGTTTTGAGGACAAGGTGTTCTATGTCTGGTTTGAT GCCACCATTGGCTATCTGTCCATCACAGCCAACTACACAGACCAATGGGAGAAGTGGTGG AAGAACCCAGAACAAGTGAACCTGTATCAGTTCATGGCCAAGGACAATGTTCCCTTCCAT GGCATAGTCTTTCCTTCTTCAGCCCTAGGAGCTGAGGACAACTACACCTTGGTCAGCCAC CTCATTGCTACAGAGTATCTGAATTACGAGGATGGGAAATTCTCTAAGAGCCGGGGTGTG GGAGTGTTTGGGGACATGGCCCAGGACACAGGGATCCCTGCTGACATCTGGCGCTTCTAT CTGCTGTACAATCGGCCTGAGGGGCAGGACAGTGCCTTCTCCTGGACAGACATGTTGTTC AAGAATAATTCCGAGCTGCTTAACAACCTGGGCAACTTCATCAACAGAGCTGGGATGTTT GTGTCCAAGTTTTTTGGGGGTTTTGTGCCTGAGATGGTGCTCACCTCTGATGATCAGCGC CTGCTGACCCATATCACCCTGGAGCTCCAGCACTACCACCAGCTGCTAGAGAAGGTTCGG ATCCGGGATGCCTTACGTAGCATCCTCACCATCTCTCGCCATGGCAACCAGTACATTCAG GTGAACGAGCCCTGGAAGCGGATTAAAGGTGGCGAAGCTGACAGGCAGCGGGCAGGGACA GTGACAGGCTTGGCCGTGAATATAGCTGCCTTGCTGTCCGTCATGCTCCAGCCTTACATG CCTACAGTTAGTGCCACCATCCAAGCCCAGCTGCAGCTCCCACCTCCAGCCTGCAGTATC CTGCCCACAAACTTCCTATGCACCTTACCAGCAGGACACCAGATTGGCACGGTCAGTCCC TTGTTCCAAAAATTGGAAAATGACCAGATTGAAAGTCTGAAGCAGCGCTTCAGTGGGGGC CAGGCAAAAGCATCCCCCAAGACAGCAGCTGGACTGACAACAGCTGGACCGCAGCAGATC CAAGCACTGACAGAGGAAGTGACCAAGCAGGGCAATATTGTCCGAGAATTGAAGGCACAG AAGGCAGACAAGAACCAGATTGCTGCAGAGGTGGCTAAACTCTTGGATCTGAAGAAACAG TTGGCTCTAGCTGAGGGGAAACCCCTGGAAACCTCTAAAGGCAAGAAGAAAAAGTGA |
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| Protein Properties | |||||
| Number of Residues | 898 | ||||
| Molecular Weight | 100634.0 | ||||
| Theoretical pI | 6.36 | ||||
| Pfam Domain Function | Not Available | ||||
| Signals |
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| Transmembrane Regions | Not Available | ||||
| Protein Sequence |
>Methionyl-tRNA synthetase, cytoplasmic MRLFVSEGAPGSLPVLAAAGRAQGRAELLISTVGPEECVVPFLTRPKVPVLQLDSGNYLF STSAICRYFFLLSGWEQDDLTNQWLEWEATELQPALSAALYYLVVQGKKGEDVLGPVRRA LTHIDHSLSRRSCPFLAGETESLADIVLWGALYPLLQDPSYLPEELGALHSWFQTLSSQE PCQRAAETVLKQQGVLALRPYLQKQPQPSSLEGRLVSNEPEEEELATLSEEEIAVAVAAW EKGLESLPPLRPQQNPVLPVAGERNVLITSALPYVNNVPHLGNIIGCVLSADVFARYSRL RQWNTLYLCGTDEYGTATETKAMEEGLTPQEICDKYHVIHADIYRWFNISFDFFGRTTTP QQTKITQDIFQRLLARGFVLQDTVEQLRCEHCARFLADRFVEGVCPFCGYEEARGDQCDK CGKLINAIELKKPQCKVCRSCPVVKSSQHLFLDLPKLAARVEEWLEKTLPGSDWTANARF IIRSWLRDGLKPRCITRDLKWGTPVPLEGFEDKVFYVWFDATIGYLSITANYTDQWEKWW KNPEQVNLYQFMAKDNVPFHGIVFPSSALGAEDNYTLVSHLIATEYLNYEDGKFSKSRGV GVFGDMAQDTGIPADIWRFYLLYNRPEGQDSAFSWTDMLFKNNSELLNNLGNFINRAGMF VSKFFGGFVPEMVLTSDDQRLLTHITLELQHYHQLLEKVRIRDALRSILTISRHGNQYIQ VNEPWKRIKGGEADRQRAGTVTGLAVNIAALLSVMLQPYMPTVSATIQAQLQLPPPACSI LPTNFLCTLPAGHQIGTVSPLFQKLENDQIESLKQRFSGGQAKASPKTAAGLTTAGPQQI QALTEEVTKQGNIVRELKAQKADKNQIAAEVAKLLDLKKQLALAEGKPLETSKGKKKK |
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| External Links | |||||
| GenBank ID Protein | AAI11363.1 | ||||
| UniProtKB/Swiss-Prot ID | Q2T9L8 | ||||
| UniProtKB/Swiss-Prot Entry Name | SYMC_BOVIN | ||||
| PDB IDs | Not Available | ||||
| GenBank Gene ID | BC111362 | ||||
| GeneCard ID | MARS1 | ||||
| GenAtlas ID | Not Available | ||||
| HGNC ID | Not Available | ||||
| References | |||||
| General References | Not Available | ||||