Identification
BMDB Protein ID BMDBP01261
Secondary Accession Numbers None
Name Hydroxyacylglutathione hydrolase, mitochondrial
Synonyms Not Available
Gene Name HAGH
Protein Type Enzyme
Biological Properties
General Function Involved in hydroxyacylglutathione hydrolase activity
Specific Function Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.
Pathways
  • (R)-lactate from methylglyoxal: step 2/2
  • Methylglyoxal degradation
  • Pyruvaldehyde Degradation
  • Pyruvate Metabolism
  • Secondary metabolite metabolism
Reactions Not Available
GO Classification Not Available
Cellular Location Not Available
Gene Properties
Chromosome Location 25
Locus Not Available
SNPs HAGH
Gene Sequence
>927 bp
ATGGTGCTGGGCCGCGGGCTGCTCGGCCGCTGGAGCGTCGCAGAGCTGGGAGCCGTCTGC
GCTCGTCTCGGCCTGGGTCCAGCCCTGCTGGGAAGCCTCCACCACTTGGGTTTAAGGAAG
AGCTTGACCGTGGATCAGGGCACCATGAAGGTGGAGTTACTGCCGGCTCTGACCGACAAT
TACATGTACCTGCTCATTGATGAGGACACCAAGGAGGCGGCCATTGTGGATCCGGTGCAG
CCCCAGAAGGTGGTGGAAACGGCGAGGAAGCACGGCGTGAAGCTGACCACAGTGCTCACC
ACCCACCACCACTGGGACCACGCTGGCGGGAACGAGAAGCTGGTCAAGCTGGAACCTGGG
TTGAAGGTGTACGGGGGTGATGACCGGATTGGGGCCCTGACTCACAAGGTCACACACCTG
TCCACACTGCAGGTGGGGTCTCTCCATGTCAAGTGCCTGTCGACGCCGTGTCACACTTCC
GGACACATCTGTTACTTTGTGACCAAGCCCAACAGTCCCGAGCCGCCCGCTGTGTTCACA
GGTGACACCTTGTTTGTGGCCGGCTGCGGGAAGTTCTATGAAGGGACAGCGGATGAGATG
TACAAAGCCCTGCTCGAGGTCCTGGGCCGGCTCCCTGCAGACACGAGAGTGTACTGTGGC
CATGAATACACCATCAACAACCTGAAGTTTGCTCGCCACGTGGAGCCCGACAACACTGCC
GTCCGGGAGAAACTGGCCTGGGCCAAGGAGAAGTACAGCATCGGGGAGCCCACGGTGCCA
TCCACCATCGCCGAGGAGTTCACCTACAACCCATTCATGCGAGTGAGGGAGAAGACGGTG
CAGCAGCACGCGGGCGAGACGGAGCCTGTGGCCACCATGAGGGCCATCCGCAAAGAGAAG
GACCAGTTCAAGATGCCGCGGGACTAG
Protein Properties
Number of Residues 308
Molecular Weight 34089.0
Theoretical pI 7.93
Pfam Domain Function Not Available
Signals
  • None
Transmembrane Regions Not Available
Protein Sequence
>Hydroxyacylglutathione hydrolase, mitochondrial
MVLGRGLLGRWSVAELGAVCARLGLGPALLGSLHHLGLRKSLTVDQGTMKVELLPALTDN
YMYLLIDEDTKEAAIVDPVQPQKVVETARKHGVKLTTVLTTHHHWDHAGGNEKLVKLEPG
LKVYGGDDRIGALTHKVTHLSTLQVGSLHVKCLSTPCHTSGHICYFVTKPNSPEPPAVFT
GDTLFVAGCGKFYEGTADEMYKALLEVLGRLPADTRVYCGHEYTINNLKFARHVEPDNTA
VREKLAWAKEKYSIGEPTVPSTIAEEFTYNPFMRVREKTVQQHAGETEPVATMRAIRKEK
DQFKMPRD
GenBank ID Protein AAI07546.1
UniProtKB/Swiss-Prot ID Q3B7M2
UniProtKB/Swiss-Prot Entry Name GLO2_BOVIN
PDB IDs
GenBank Gene ID BC107545
GeneCard ID HAGH
GenAtlas ID Not Available
HGNC ID Not Available
References
General References Not Available