Identification |
BMDB Protein ID
| BMDBP01261 |
Secondary Accession Numbers
| None |
Name
| Hydroxyacylglutathione hydrolase, mitochondrial |
Synonyms
|
Not Available
|
Gene Name
| HAGH |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in hydroxyacylglutathione hydrolase activity |
Specific Function
| Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. |
Pathways
|
- (R)-lactate from methylglyoxal: step 2/2
- Methylglyoxal degradation
- Pyruvaldehyde Degradation
- Pyruvate Metabolism
- Secondary metabolite metabolism
|
Reactions
| Not Available |
GO Classification
|
Not Available
|
Cellular Location
|
Not Available
|
Gene Properties |
Chromosome Location
| 25 |
Locus
| Not Available |
SNPs
| HAGH |
Gene Sequence
|
>927 bp
ATGGTGCTGGGCCGCGGGCTGCTCGGCCGCTGGAGCGTCGCAGAGCTGGGAGCCGTCTGC
GCTCGTCTCGGCCTGGGTCCAGCCCTGCTGGGAAGCCTCCACCACTTGGGTTTAAGGAAG
AGCTTGACCGTGGATCAGGGCACCATGAAGGTGGAGTTACTGCCGGCTCTGACCGACAAT
TACATGTACCTGCTCATTGATGAGGACACCAAGGAGGCGGCCATTGTGGATCCGGTGCAG
CCCCAGAAGGTGGTGGAAACGGCGAGGAAGCACGGCGTGAAGCTGACCACAGTGCTCACC
ACCCACCACCACTGGGACCACGCTGGCGGGAACGAGAAGCTGGTCAAGCTGGAACCTGGG
TTGAAGGTGTACGGGGGTGATGACCGGATTGGGGCCCTGACTCACAAGGTCACACACCTG
TCCACACTGCAGGTGGGGTCTCTCCATGTCAAGTGCCTGTCGACGCCGTGTCACACTTCC
GGACACATCTGTTACTTTGTGACCAAGCCCAACAGTCCCGAGCCGCCCGCTGTGTTCACA
GGTGACACCTTGTTTGTGGCCGGCTGCGGGAAGTTCTATGAAGGGACAGCGGATGAGATG
TACAAAGCCCTGCTCGAGGTCCTGGGCCGGCTCCCTGCAGACACGAGAGTGTACTGTGGC
CATGAATACACCATCAACAACCTGAAGTTTGCTCGCCACGTGGAGCCCGACAACACTGCC
GTCCGGGAGAAACTGGCCTGGGCCAAGGAGAAGTACAGCATCGGGGAGCCCACGGTGCCA
TCCACCATCGCCGAGGAGTTCACCTACAACCCATTCATGCGAGTGAGGGAGAAGACGGTG
CAGCAGCACGCGGGCGAGACGGAGCCTGTGGCCACCATGAGGGCCATCCGCAAAGAGAAG
GACCAGTTCAAGATGCCGCGGGACTAG
|
Protein Properties |
Number of Residues
| 308 |
Molecular Weight
| 34089.0 |
Theoretical pI
| 7.93 |
Pfam Domain Function
|
Not Available |
Signals
|
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Hydroxyacylglutathione hydrolase, mitochondrial
MVLGRGLLGRWSVAELGAVCARLGLGPALLGSLHHLGLRKSLTVDQGTMKVELLPALTDN
YMYLLIDEDTKEAAIVDPVQPQKVVETARKHGVKLTTVLTTHHHWDHAGGNEKLVKLEPG
LKVYGGDDRIGALTHKVTHLSTLQVGSLHVKCLSTPCHTSGHICYFVTKPNSPEPPAVFT
GDTLFVAGCGKFYEGTADEMYKALLEVLGRLPADTRVYCGHEYTINNLKFARHVEPDNTA
VREKLAWAKEKYSIGEPTVPSTIAEEFTYNPFMRVREKTVQQHAGETEPVATMRAIRKEK
DQFKMPRD
|
External Links |
GenBank ID Protein
| AAI07546.1 |
UniProtKB/Swiss-Prot ID
| Q3B7M2 |
UniProtKB/Swiss-Prot Entry Name
| GLO2_BOVIN |
PDB IDs
|
|
GenBank Gene ID
| BC107545 |
GeneCard ID
| HAGH |
GenAtlas ID
| Not Available |
HGNC ID
| Not Available |
References |
General References
| Not Available |