Showing Protein Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 (BMDBP01297)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01297 |
| Secondary Accession Numbers | None |
| Name | Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 |
| Synonyms | Not Available |
| Gene Name | GCNT3 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in beta-1,3-galactosyl-O-glycosyl-glycoprotein |
| Specific Function | Glycosyltransferase that can synthesize all known mucin beta 6 N-acetylglucosaminides. Mediates core 2 and core 4 O-glycan branching, 2 important steps in mucin-type biosynthesis. Has also I-branching enzyme activity by converting linear into branched poly-N-acetyllactosaminoglycans, leading to introduce the blood group I antigen during embryonic development. |
| Pathways |
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| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 10 |
| Locus | Not Available |
| SNPs | GCNT3 |
| Gene Sequence |
>1323 bp ATGAAGATGACTGGGTGGAAGAAGAAGCTTTGCCGGGGGCATCATCTGTGGGCTCTGGGC TGCTATATGCTGCTGGCCGTTGTTGCTCTGAGGCTTTCTCTCAGGTTGAAATGTGATGTA GATTCCTTGGATCTGGAGTCCAGGGACTTCCAAAGTCAGCGTTGTAGGGACGTCTTGTAC AAGAACCTGAAGCTGCCAGCAAAGAGATCCATCAACTGTTCTGGGATCACACGAGGGGAC CAGGAAGCGGTGGTCCAGGCTCTCCTGGACAACCTGGAAGTCAAGAAGAAGCGGTTGCCT TTCACTGACACCTATTACCTCAACATAACCAGAGACTGTGAGCAGTTTAAGGCCCAAAGG AAGTTCATACAGTTCCCACTGAGCAAAGAAGAGTTAGACTTCCCCATTGCATACTCGATG GTGGTCCATGAGAAGATTGAAAACTTTGAACGGCTGCTGCGAGCTGTGTATGCCCCTCAG AACATATACTGTGTCCATGTGGATGTGAAGTCCCCAGAAACTTTCAAAGAGGCAGTCAAG GCCATTATTTCCTGCTTCCCCAATGTCTTCATGGCCAGTAAGTTGGTCCCAGTGGTTTAT GCCTCCTGGTCCAGAGTGCAGGCTGACCTGAACTGTATGGAAGACTTGCTCCAGAGCTCG GTGCCATGGAAATACTTACTGAATACATGTGGGACAGACTTCCCCATAAAGACCAACGCC GAGATGGTTCTGGCCCTCAAGATGTTGAATGGGAAGAACAGTATGGAGTCTGAGATACCT TCTGAGTCCAAAAAAAATCGCTGGAAATACCGCTATGAGGTGACAGACAGACTGTACCTA ACCAGCAAGATGAAGGACCCTCCCCCTGATAATTTACCTATGTTCACGGGGAATGCCTAT TTTGTGGCTTCTCGAGCCTTTGTCCAACATGTCTTAGAGAACCCCAAATCCCAAAGACTG ATTGAATGGGTCAAAGACACCTATAGCCCCGACGAACACCTCTGGGCCACCCTTCAGCGT GCTCCATGGATGCCTGGCTCTGTTCCTTACCACCCCAAGTATCACATCTCAGACATGACT GCCATCGCCAGGCTGGTCAAGTGGCAGGGCCACGAGGGAGATGTCAGCATGGGGGCGCCT TATGCACCCTGCTCTGGAATCCATCAGCGGGCCATCTGCATTTACGGGGCCGGGGACCTG CACTGGATTCTCCAGAACCATCACCTCTTGGCAAACAAGTTTGACCCAAGGGTGGATGAT AACGTCCTGCAGTGCTTAGAAGAGTATTTACGTCATAAGGCCATCTATGGGACTGAACTT TGA |
| Protein Properties | |
| Number of Residues | 440 |
| Molecular Weight | 50953.0 |
| Theoretical pI | 8.65 |
| Pfam Domain Function | Not Available |
| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 MKMTGWKKKLCRGHHLWALGCYMLLAVVALRLSLRLKCDVDSLDLESRDFQSQRCRDVLY KNLKLPAKRSINCSGITRGDQEAVVQALLDNLEVKKKRLPFTDTYYLNITRDCEQFKAQR KFIQFPLSKEELDFPIAYSMVVHEKIENFERLLRAVYAPQNIYCVHVDVKSPETFKEAVK AIISCFPNVFMASKLVPVVYASWSRVQADLNCMEDLLQSSVPWKYLLNTCGTDFPIKTNA EMVLALKMLNGKNSMESEIPSEYKKNRWKYRYEVTDRLYLTSKMKDPPPDNLPMFTGNAY FVASRAFVQHVLENPKSQRLIEWVKDTYSPDEHLWATLQRAPWMPGSVPYHPKYHISDMT AIARLVKWQGHEGDVSMGAPYAPCSGIHQRAICIYGAGDLHWILQNHHLLANKFDPRVDD NVLQCLEEYLRHKAIYGTEL |
| External Links | |
| GenBank ID Protein | AAO22165.1 |
| UniProtKB/Swiss-Prot ID | Q7YQE1 |
| UniProtKB/Swiss-Prot Entry Name | GCNT3_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | AF465338 |
| GeneCard ID | GCNT3 |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |