| Identification |
|---|
| BMDB Protein ID
| BMDBP01300 |
| Secondary Accession Numbers
| None |
| Name
| Glucosidase 2 subunit beta |
| Synonyms
|
Not Available
|
| Gene Name
| PRKCSH |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins (By similarity). Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (By similarity). |
| Pathways
|
- Glycan metabolism
- N-glycan metabolism
|
| Reactions
| Not Available |
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 7 |
| Locus
| Not Available |
| SNPs
| PRKCSH |
| Gene Sequence
|
>1602 bp
ATGTTACTGCTGCTGCTGCTACTGCCGATGTGTTGGGCCGTGGAAGTCAGGCGACCCCGG
GGCGTCTCCCTCACCAACCATCACTTCTACGACGAGTCAAAGCCTTTCACTTGCCTGGAT
GGCTCTGCCAGTATCCCCTTTGATCAGGTCAATGATGACTACTGTGACTGCAAAGATGGC
TCAGATGAACCAGGCACAGCTGCCTGTCCCAACGGCAGCTTCCACTGCACCAACACAGGC
TACAAGGCCCTGTACATCTCCTCCAGATGGGTCAACGATGGAGTGTGTGACTGCTGTGAC
GGGACCGACGAATACAACAGCGGGATCGTTTGTGAGAACACCTGCAAAGAGAAGGGCCGC
AAGGAGAGAGAGACACTGCAGCAGATGGCAGAGGTGACCCGCGAGGGCTTCCGCCTGAAG
AAGATCCTGATTGAGGACTGGAAGAAGGCCCGGGAGGAGAAGCAGAAAAAGCTCATTGAG
CTGCAGGCTGGAAAGAAGTCACTGGAGGACCAGGTGGAGGTGCTGCGGACCCTGAAGGAG
GAAGCCGAGAAGCCAGAGGAGGCGGCCAAAGACCAGCACCGCAGGCTGTGGGAAGAGCAG
CAGGCCATCTCCAAGGAGCAGCGGGAGCGGGAGCTGGCAGCCAGCGCCTTCCAGGAGCTG
GATGATGACATGGATGGCGCGGTCTCAGTGGCTGAGCTGCAGACCCACCCAGAGCTGGAC
ACGGATGGGGACGGGGCATTATCAGAAGGGGAAGCCCAGACCCTCCTTGGGGGAGACGCG
CAGATGGATGCTGCTTTCTTCTATGACCGTGTCTGGGCCGCCATCAGGGACAAGTACCGG
TCCGAGGTGCTGCCCACTGAGTACCCACCATCGCCTCCTGCACCCGATGTGATGGAGCCC
AAGGAGGAGCAGCCCCCCATGCCCTCACCGCCCACAGAGGAGGAGGACGAAGACGAGGAG
GACGAGGAGACAGAGGAGGATGAGGATGAGGAGGACGAGGATTCCCAGGGGGAGCAGCCC
AAGGACGCCCCACCCCCAGCCCCAGCCCCCCAGACGGCCAGCCCCACCGAGGAGGATAGG
ATGCCGCCGTATGATGAGCAGACGCAGGCCTTCATCAATGCTGCCCAGGAGGCCCGCAAC
AAGTTCGAAGAGGCTGAGCGGTCCCTGAAGGACATGGAAGAATCCATCAGGAACCTGGAA
CAGGAGATTTCATTTGATTTTGGCCCCAACGGCGAGTTCGCCTACCTGTACAGCCAGTGC
TATGAGCTCACCACCAATGAGTACGTCTACAGACTCTGCCCCTTCAAGCTTGTCTCACAG
AAACCCAAACTCGGCGGCTCCCCTACCAGCCTTGGCACCTGGGGCTCGTGGGCTGGCCCC
GACCACGACAAGTTCAGCGCCATGAAGTATGAGCAGGGCACAGGCTGCTGGCAGGGCCCC
AATCGCTCCACCACCGTGCGCCTGCTGTGCGGGAAGGAGACGGTGGTGACCAGCACCACA
GAGCCCAGCCGCTGCGAGTACCTCATGGAGCTGATGACGCCAGCTGCCTGCCCAGAGCCC
CCGCCTGAATACCCAGTGGAGGGCGACCATGATGAGCTCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 533 |
| Molecular Weight
| 60151.0 |
| Theoretical pI
| 4.08 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Glucosidase 2 subunit beta
MLLLLLLLPMCWAVEVRRPRGVSLTNHHFYDESKPFTCLDGSASIPFDQVNDDYCDCKDG
SDEPGTAACPNGSFHCTNTGYKALYISSRWVNDGVCDCCDGTDEYNSGIVCENTCKEKGR
KERETLQQMAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEVLRTLKE
EAEKPEEAAKDQHRRLWEEQQAISKEQRERELAASAFQELDDDMDGAVSVAELQTHPELD
TDGDGALSEGEAQTLLGGDAQMDAAFFYDRVWAAIRDKYRSEVLPTEYPPSPPAPDVMEP
KEEQPPMPSPPTEEEDEDEEDEETEEDEDEEDEDSQGEQPKDAPPPAPAPQTASPTEEDR
MPPYDEQTQAFINAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQC
YELTTNEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWAGPDHDKFSAMKYEQGTGCWQGP
NRSTTVRLLCGKETVVTSTTEPSRCEYLMELMTPAACPEPPPEYPVEGDHDEL
|
| External Links |
|---|
| GenBank ID Protein
| AAA92060.1 |
| UniProtKB/Swiss-Prot ID
| Q28034 |
| UniProtKB/Swiss-Prot Entry Name
| GLU2B_BOVIN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| U49178 |
| GeneCard ID
| PRKCSH |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
