Showing Protein Complement C1s subcomponent (BMDBP01303)
| Identification | |
|---|---|
| BMDB Protein ID | BMDBP01303 |
| Secondary Accession Numbers | None |
| Name | Complement C1s subcomponent |
| Synonyms | Not Available |
| Gene Name | C1S |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in calcium ion binding |
| Specific Function | C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4 (By similarity). |
| Pathways |
|
| Reactions | Not Available |
| GO Classification | Not Available |
| Cellular Location | Not Available |
| Gene Properties | |
| Chromosome Location | 5 |
| Locus | Not Available |
| SNPs | C1S |
| Gene Sequence |
>2088 bp ATGAACAAATTGCCAGAGATGTGGTGCATTGTCCTGTTTTCCCTTGTGGCCTGGGTTTAT GCCGAGCCTACTATGTATGGAGAGATTCTATCCCCCAACTACCCTCAGGTGTACCCCAAC GAGGTCGAGAAGTCTTGGGACATAGAAGTCCCTGCAGGGTACGGGATCCACCTTTACTTC ACCCACCTGGATATAGAGTTGTCTGAGAACTGCTCCTATGATTCAGTGCAGATAATGTCG GGAGGCCATGAAGAAGGGAAACTCTGTGGACGGAGGACCAACAAGAATTCAAACTCCCCA GTGGTGAAAGAGTTCCACATCCCATACAGTAAATTGCAGGTGATCTTCCGGTCGGACTTC TCCAACGAGGAGCGTTTCACCGGGTTTGCTGCGTACTATGTTGCTGAGGATATAGATGAG TGCACAGCCTTTGCAGATGCTCCTTGCAGCCACTTCTGCAATAACTTCCTTGGTGGTTAC TTCTGCTCCTGCCCTCCAGAATACTTCCTCCATGAAGACAAGAAGAACTGTGGAGTCAAT TGCAGTGGAAATGTATTCACCACAATGACTGGGGAGGTTGAAAGTCCTAATTACCCCAGT CCATACCCAGAGAGCTCAAGGTGTGACTATCAGATCCAGTTGGAGGAGGGGTTCCGAGTG GTGGTGACCATGAGGAGAGAAGACTTTGATGTGGAACCAGCTGACTCCGAGGGCCACTGT CCCGACAGTTTGCTCTTTGTGGCAGGAGACCAGCATTTTGGTCCTTACTGTGGGAACGGC TTTCCTGGGCCACTAACAATTGAAACCCAGAGCAGTGCTCTGAATATCATCTTCCAAACT GATGGATCAGAACAAAGAAAGGGATGGAAATTTCGTTACCATGGAGATCCAATCCCTTGT CCTAAAGAAGTCACTGCCAATTCCTTCTGGGAGCCTGAGAGAGCAAAATATGTGTTCAGA GATGTGGTGAAGATAACCTGTGTGGATGGGTTTGAAGTTGTGCAGGGAAGTGTTGGTTCC CCATCTTTCTACTCTACTTGTCAAAGCAATGGAAAGTGGAGTAATTCCAAGTTGCGGTGT CAACCCGTGGACTGTGGCGCTCCTGAACCCATTCAGCATGGTAGAGTCGAAGATCCAGAA AGTACTCTATTTGGTTCCATCACTCGCTACTCTTGTGAGATGCCATATTACAGCATGGAA TGTGAAGGGAGCGAGGTGTATCACTGCAGTGGCAATGGGAGCTGGGTGAACAAGGTGCTG GGCATAGAGCCGCCGAAATGCATTGCAGTCTGTGGCACCCCCAGCGAGCCTTTTAGATCA ACACAAAGAATATTTGGAGGCTCCATTGCGAAGATTGAAAATTTCCCCTGGCAAGTCTTC TTCTCGAACCCATGGGCTGGTGGGGCTCTCATTGATGAATACTGGGTGCTGACAGCTGCC CATGTCGTGGAGGGAAACGATATCCCAGTGATGTATGTTGGGTCCTCCTCAGTGGTCACC TCACAATTGTCAAATGCTCAGATGCTCACTGCAGAGAGAGTGTTTATCCATCCAGGATGG GAGGTCCTGGATCCTTCGATAACACGAAAGAATTTTGACAATGACATTGCGCTGGTGCGG CTGAGAGACCCAGTGAAAATGGGACCCAAGGTCGCCCCTATCTGCCTACCAGGCACCTCC TCAGAATATGACCCTCCGGAGAACGTCCTGGGCCTGATCTCAGGTTGGGGTCGAACAAAT GTCAAAAGTCATGTTATTAAGCTCAGAGGGGCAAAGCTACCCGTTGCTCCCTTATCCAAA TGCCGGGAGATGAAGGGGGTCAATCCTGGAATAGATATCAGTTCTTTTGTTTTCACTGAG AACATGATCTGTGCCGGTAATGACAAGGGTGTTGACAGCTGTGACGGGGACAGTGGTGGG GCCTTTGCTGTACAGGACCCTAAGGAAAACAAGCCCAAATTCTATGTTGCTGGTTTGGTG TCCTGGGGCCCCCAGTGTGGGACCTATGGGATCTACACGCGAGTCAAGAACTACGTTGAC TGGATAAGGAAGACAATGCAGGAGTATAGTGCCCCCAGTGTAGACTAA |
| Protein Properties | |
| Number of Residues | 689 |
| Molecular Weight | 76609.0 |
| Theoretical pI | 4.72 |
| Pfam Domain Function | Not Available |
| Signals |
|
| Transmembrane Regions | Not Available |
| Protein Sequence |
>Complement C1s subcomponent MWCIVLFSLVAWVYAEPTMYGEILSPNYPQVYPNEVEKSWDIEVPAGYGIHLYFTHLDIE LSENCSYDSVQIMSGGHEEGKLCGRRTNKNSNSPVVKEFHIPYSKLQVIFRSDFSNEERF TGFAAYYVAEDIDECTAFADAPCSHFCNNFLGGYFCSCPPEYFLHEDKKNCGVNCSGNVF TTMTGEVESPNYPSPYPESSRCDYQIQLEEGFRVVVTMRREDFDVEPADSEGHCPDSLLF VAGDQHFGPYCGNGFPGPLTIETQSSALNIIFQTDGSEQRKGWKFRYHGDPIPCPKEVTA NSFWEPERAKYVFRDVVKITCVDGFEVVQGSVGSPSFYSTCQSNGKWSNSKLRCQPVDCG APEPIQHGRVEDPESTLFGSITRYSCEMPYYSMECEGSEVYHCSGNGSWVNKVLGIEPPK CIAVCGTPSEPFRSTQRIFGGSIAKIENFPWQVFFSNPWAGGALIDEYWVLTAAHVVEGN DIPVMYVGSSSVVTSQLSNAQMLTAERVFIHPGWEVLDPSITRKNFDNDIALVRLRDPVK MGPKVAPICLPGTSSEYDPPENVLGLISGWGRTNVKSHVIKLRGAKLPVAPLSKCREMKG VNPGIDISSFVFTENMICAGNDKGVDSCDGDSGGAFAVQDPKENKPKFYVAGLVSWGPQC GTYGIYTRVKNYVDWIRKTMQEYSAPSVD |
| External Links | |
| GenBank ID Protein | AAI19957.1 |
| UniProtKB/Swiss-Prot ID | Q0VCX1 |
| UniProtKB/Swiss-Prot Entry Name | C1S_BOVIN |
| PDB IDs | Not Available |
| GenBank Gene ID | BC119956 |
| GeneCard ID | C1S |
| GenAtlas ID | Not Available |
| HGNC ID | Not Available |
| References | |
| General References | Not Available |