| Identification |
|---|
| BMDB Protein ID
| BMDBP01304 |
| Secondary Accession Numbers
| |
| Name
| Alpha-lactalbumin |
| Synonyms
|
Not Available
|
| Gene Name
| LALBA |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in calcium ion binding |
| Specific Function
| Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins. |
| Pathways
|
Not Available
|
| Reactions
|
| D-Glucose + Uridine diphosphategalactose → Uridine 5'-diphosphate + Alpha-Lactose |
details
|
|
| GO Classification
|
Not Available
|
| Cellular Location
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 5 |
| Locus
| 5q21 |
| SNPs
| LALBA |
| Gene Sequence
|
>429 bp
AMOFALUISITE.TAACCAAAATGATGTCCTTTGTCTCTCTGCTCCTGGTAGGCATCCTA
TTCCATGCCACCCAGGCTGAACAGTTAACAAAATGTGAGGTGTTCCGGGAGCTGAAAGAC
TTGAAGGGCTACGGAGGTGTCAGTTTGCCTGAATGGGTCTGTACCACGTTTCATACCAGT
GGTTATGACACACAAGCCATAGTACAAAACAATGACAGCACAGAATATGGACTCTTCCAG
ATAAATAATAAAATTTGGTGCAAAGACGACCAGAACCCTCACTCAAGCAACATCTGTAAC
ATCTCCTGTGACAAGTTCCTGGATGATGATCTTACTGATGACATTATGTGTGTCAAGAAG
ATTCTGGATAAAGTAGGAATTAACTACTGGTTGGCCCATAAAGCACTCTGTTCTGAGAAG
CTGGATCAG
|
| Protein Properties |
|---|
| Number of Residues
| 142 |
| Molecular Weight
| 16247.0 |
| Theoretical pI
| 4.73 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Alpha-lactalbumin
MMSFVSLLLVGILFHATQAEQLTKCEVFRELKDLKGYGGVSLPEWVCTTFHTSGYDTQAI
VQNNDSTEYGLFQINNKIWCKDDQNPHSSNICNISCDKFLDDDLTDDIMCVKKILDKVGI
NYWLAHKALCSEKLDQWLCEKL
|
| External Links |
|---|
| GenBank ID Protein
| CAA29664.1 |
| UniProtKB/Swiss-Prot ID
| P00711 |
| UniProtKB/Swiss-Prot Entry Name
| LALBA_BOVIN |
| PDB IDs
|
|
| GenBank Gene ID
| X06366 |
| GeneCard ID
| LALBA |
| GenAtlas ID
| Not Available |
| HGNC ID
| Not Available |
| References |
|---|
| General References
| Not Available |
